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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Chronic pelvic pain,psychiatric disorders and early emotional traumas:Results of a cross sectional case-control study显示文摘AIM To compare the prevalence of psychiatric disorders and early emotional traumas between women with chronic pelvic pain(CPP) and healthy women.METHODS One hundred women in reproductive age,50 of them had CPP(according to the criteria set by the International Association for Study of Pain),and 50 were considered healthy after the gynecological evaluation.The eligibility criteria were defined as follows:chronic or persistent pain perceived in the pelvis-related structures(digestive,urinary,genital,myofascial or neurological systems).Only women in reproductive age with acyclic pain for 6 mo,or more,were included in the present study.Menopause was the exclusion criterion.The participants were grouped according to age,school level and socioeconomic status and were individually assessed through DSM-IV Structured Clinical Interview(SCID-I) and Early Trauma Inventory Self-report-short form(ETISR-SF Brazilian version).Descriptive statistics,group comparison tests and multivariate logistics regression were used in the data analysis.RESULTS The early emotional traumas are highly prevalent,but their prevalence did not differ between the two groups.The current Major Depressive Disorder was more prevalent in women with CPP.The CPP was associatedwith endometriosis in 48% of the women.There was no difference in the prevalence of disorders when endometriosis was taken into account(endometriosis vs other diseases:P > 0.29).The current Major Depressive Disorder and the Bipolar Disorder had greater occurrence likelihood in the group of women with CPP(ODDS = 5.25 and 9.0).CONCLUSION The data reinforce the link between mood disorders and CPP.The preview evidences about the association between CPP and early traumas tended not to be significant after a stronger methodological control was implemented. | Flávia L Osório Ana Carolina F Carvalho Mariana F Donadon André L Moreno Omero Polli-Neto | 2016 | World Journal of Psychiatry2016，6，3： | 2 |
| 3 | Integrative genomic approa- ches highlight a family of parasite-specific kinases that regulate host responses显示文摘 | Peixoto L Chen F Harb OS | 2010 | Cell Host Micro2010，8，2： | 1 |
| 4 | Food safety performance indicators to benchmark food safety output of food safety management systems Original Research Article 显示文摘 | L JACXSENS M UYTTENDAELE F DEVLIEGHERE J ROVIRA S OSES GOMEZ P A LUNING | 2010 | International Journal of Food Microbiology2010，141，1： | 1 |
| 5 | The formation of Pliocene sapropels and carbonate cycles in the Mediterranean: Diagenesis, dilution, and productivity 显示文摘 | Van Os B J H Lourens L J Hilgen F J | 1994 | Paleoceanography1994，9，： | 1 |
| 6 | Production of Th1/Th2 cytokines and nitric oxide in Behcet' s uveitis and idiopathic uveitis 显示文摘 | Guenane H Hartani D Chachoua L Lahlou-Boukoffa OS Mazari F Touil-Boukoffa C | 2006 | J Fr Ophthalmol2006，29，2： | 1 |
| 7 | Effect of Concentration on the Primary and Ultimate Biodegradation of Alkylpolyglucosides in Aerobic Biodegradation Tests显示文摘 | Jurado E Fernández-Serrano M Núnez-Olea J Lechuga M Jiménez J L Ríos F | 2011 | Water Environment Research2011，，2： | 1 |
| 8 | Integrative genomic ap- proaches highlight a family of pm'asite-specific kinases that regulate host responses显示文摘 | Peixoto L Cilen F Harb OS | 2010 | Cell Host Microbe2010，8，： | 1 |
| 9 | Fatigue properties of a 4340 steel coated with a Colmonoy 88 deposit applied by high-velocity oxygen fuel显示文摘 | Hernández L Oliveira F Berríos J A | 2000 | Surface and Coatings Technology2000，，133134： | 1 |
| 10 | Integrative genomic approach- es highlight a family of parasite-specific kinases that regulate host responses显示文摘 | Peixoto L Chen F Harb OS | 2010 | Cell Host Microbe2010，8，2： | 1 |
| 11 | Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses显示文摘 | Peixoto L Chen F Harb OS | 2010 | Cell Host Microbe2010，8，2： | 1 |
| 12 | Effect of Concentration on the Primary and Ultimate Biodegradation of Alkylpolyglucosides in Aerobic Biodegradation Tests显示文摘 | Jurado E Fernández-Serrano M Núnez-Olea J Lechuga M Jiménez J L Ríos F | 2011 | Water Environment Research2011，，2： | 1 |
| 13 | Integrategrative genomi-capproaches highlight a family of parasite-specific kinases that regulate host responses显示文摘 | Peixoto L Chen F Harb OS | 2010 | Cell Host Microb2010，8，2： | 1 |
| 14 | Proliferating trichilemmal cyst with focal invasion:report of a case and a review of the literature显示文摘 | López-Ríos F Rodríguez-Peralto JL Aguilar A | 2000 | Am J Dermatopathol2000，22，2： | 1 |
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