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| 1 | User Driven Innovation in the Building Process显示文摘During the late years there has been an ever-increasing focus on the possibilities to change the building process to raise quality on the final building products as well as the activities of actors involved in the building process. One reason for this interest is the new opportunities evolving due to introduction of advanced information and communication technology (ICT). The paper focuses on creative changes of the building process powered by user driven innovation activities. An overview of existing user driven innovation methodologies is given as well experiences from the ongoing Virtual Innovation in Construction (VIC) project. One important driving force for change is the opportunity for users to develop and articulate real needs concerning for example different functionalities of a building and its parts, but also on artifacts supporting the actual needs capture and requirements formulation during building design. A general methodological framework and meta ontology for Virtual Innovation in Construction is presented as well as findings from implementation of the method. | Per Christiansson Kistian Birch Sφrensen Mette Rφdtness Mette Abrahamsen Lars Ostenfeld Riemnann Morten Alsdorf | 2008 | Tsinghua Science and Technology2008，13，S1： | 4 |
| 2 | Depiction of secondary metabolites and antifungal activity of Bacillus velezensis DTU001显示文摘For a safe and sustainable environment,effective microbes as biocontrol agents are in high demand.We have isolated a new Bacillus velezensis strain DTU001,investigated its antifungal spectrum,sequenced its genome,and uncovered the production of lipopeptides in HPLC-HRMS analysis.To test the antifungal efficacy,extracts of B.velezensis DTU001 was tested against a range of twenty human or plant pathogenic fungi.We demonstrate that inhibitory potential of B.velezensis DTU001 against selected fungi is superior in comparison to single lipopeptide,either iturin or fengycin.The isolate showed analogous biofilm formation to other closely related Bacilli.To further support the biocontrol properties of the isolate,coculture with Candida albicans demonstrated that B.velezensis DTU001 exhibited excellent antiproliferation effect against C.albicans.In summary,the described isolate is a potential antifungal agent with a broad antifungal spectrum that might assist our aims to avoid hazardous pathogenic fungi and provide alternative to toxicity caused by chemicals. | Sagarika Devi Heiko T.Kiesewalter Renato Kovacs Jens Christian Frisvad Tilmann Weber Thomas Ostenfeld Larsen Akos T.Kovacs Ling Ding | 2019 | Synthetic and Systems Biotechnology2019，4，3： | 4 |
| 3 | Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell prolifereation with extensive axonal outgrowth following transplantation显示文摘 | Ostenfeld T Caldwell MA Prowse KR | 2000 | Exp Neuol2000，164，： | 1 |
| 4 | The miR-143/-145 clus- ter regulates plasminogen activator inhibitor-1 in bladder cancer显示文摘 | Villadsen SB Bramsen JB Ostenfeld MS | 2012 | Br J Cancer2012，106，2： | 1 |
| 5 | Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell proliferation with extensive axonal outgrowth following transplantion显示文摘 | Ostenfeld T Caldwell MA Prowse KR | 2000 | Exp Neurol2000，164，： | 1 |
| 6 | Human neuronal stem cells : isolation, expansion, and transplantation 显示文摘 | Svendsen CN Caldwell MA Ostenfeld T | 1999 | Brain Pathol1999，9，： | 1 |
| 7 | Genomic profiling of microRNAs in bladder cancer:miR-129 is associated with poor outcome and promotes cell death in vitro显示文摘 | Dyrskj?t L Ostenfeld MS Bramsen JB | 2009 | Cancer Res2009，69，11： | 1 |
| 8 | Regional specification of rodent and human neurospheres显示文摘 | Ostenfeld T Joly E Tai YT | 2002 | Dev Brain Res2002，134，1： | 1 |
| 9 | Recent advances in stern cell neurobiolog 显示文摘 | Ostenfeld T Svendsen CN | 2003 | Adv Tech Stand Neurosurg2003，28，： | 1 |
| 10 | Transgenesis changes body and head shape in Pacific salmon 显示文摘 | Ostenfeld T H Devhn R H Mclean E | 1998 | J Fish Biol1998，52，： | 1 |
| 11 | Human neural stem cells: isolation, expansion and transplantation显示文摘 | Svendsen CN Caldwell MA Ostenfeld T | 1999 | Brain Pathol1999，9，3： | 1 |
| 12 | Com- parison of different views with three - dimen- sional echocardiography: apical views offer superior visualization compared with paraster- hal and subcostal views 显示文摘 | Ostenfeld E Shahgaldi K Winter R | 2008 | Clin Physiol Funet Imaging2008，28，26： | 1 |
| 13 | Mouse epidermal growth factor-responsive neural precursor cells increase the survival and functional capacity of embryonic rat dopamine neurons in vitro显示文摘 | Ostenfeld T Horn P Aardal C | 1999 | Neuroreport1999，10，9： | 1 |
| 14 | Diagnostic and prognostic microRNAs in stage Ⅱ colon cancer显示文摘 | Schepeler T Reinert Jr Ostenfeld MS | 2008 | Cancer Res2008，68，15： | 1 |
| 15 | The miR-143/-145 cluster regulates plasminogen activator inhibitor-1 in bladder cancer 显示文摘 | Villadsen SB Bramsen JB Ostenfeld MS | 2012 | Sr J Cancer2012，106，2： | 1 |
| 16 | Regional specification of rodent and human neurospheres 显示文摘 | Ostenfeld T Joly E Tai YT | 2002 | Dev Brain Res2002，134，： | 1 |
| 17 | Diagnostic and prog- nostic microRNAs in stage Ⅱ colon cancer显示文摘 | Schepeler T Reinert JT Ostenfeld MS | 2008 | Cancer Res2008，68，15： | 1 |
| 18 | Comparison of different methods for collection of volatile chemical markers from fungi显示文摘 | THOMAS OSTENFELD LARSEN JENS CHRISTIAN FRISVAD | 1995 | J Microbiological Methods1995，24，： | 1 |
| 19 | miR-145 induces caspase- dependent and-independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors 显示文摘 | Ostenfeld M Bramsen JB Lamy P | 2010 | Oncogene2010，29，7： | 1 |
| 20 | Diagnostic andprognostic microRNAs in stage II colon cancer显示文摘 | Schepeler T Reinert JT Ostenfeld MS | 2008 | Cancer Res2008，68，15： | 1 |
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