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| 1 | Role of Adiponectin and Its Receptors in Cancer显示文摘Adiponectin(APN),a novel hormone/cytokine derived from adipocyte tissue,is involved in various physiological functions. Genetics,nutrition,and adiposity are factors contributing to circulating plasma concentrations of APN.Clinical correlation studies have shown that lower levels of serum APN are associated with increased malignancy of various cancers,such as breast and colon cancers,suggesting that APN has a role in tumorigenesis.APN affects insulin resistance,thus further influencing cancer development. Tumor cells may express receptors for APN.Cellular signaling is the mechanism by which APN exerts its host-protective responses. These factors suggest that serum APN levels and downstream signaling targets of APN may serve as potential diagnostic markers for malignancies.Further research is necessary to clarify the exact role of APN in cancer diagnosis and therapy. | Stephanie Obeid Lionel Hebbard | 2012 | Clinical oncology and cancer resexreh2012，9，4： | 7 |
| 2 | Myxedema ascites with high CA-125:Case and a review of literature显示文摘Ascites appearing in a previously healthy female patient is usually ascribed to a variety of causes,among which,is a cancerous process,especially if it comes with a raised CA-125 level.Although the CA-125 antigen is present on more than 80% of malignant epithelial ovarian tissue of non-mucinous type,it is also found on both healthy and malignant cells of mesothelial and non-mesothelial origin.Myxedema ascites which is caused by hypothyroidism is a rare entity,but on the other hand is easy to treat.It is one of the differential diagnoses when the ascites is refractory to treatment and no other obvious cause can be identified.If the diagnosis is delayed,patients will frequently receive unnecessary procedures,while treatment has very good response rates and ascites resolve with serum CA-125 normalization after adequate hormonal treatment. | Bou Khalil Roula El Rassi Patrick Chammas Nizar Obeid Jean Ghabach Maroun Sakr Charles Itani Tarek Farhat Said | 2013 | World Journal of Hepatology2013，5，2： | 4 |
| 3 | Immunogenic chemotherapy: Discovery of a critical protein through proteomic analyses of tumor cells显示文摘 | Apetoh L Obeid M Tesniere A | 2007 | Cancer Genomics Proteomics2007，4，2： | 1 |
| 4 | Plasma homocysteine concentrations and risk of coronary heart disease in UK Indian Asian and European men显示文摘 | Chambers JC Obeid OA Refsum H | 2000 | Lancet2000，355，9203： | 1 |
| 5 | Ceramide: an intracellular signal for apoptosis显示文摘 | HannunYA Obeid LM | 1995 | TIBS1995，20，2： | 1 |
| 6 | The use of curare during anesthesia to prevent iatrogenic muscle damage caused by lumbar spinal surgery through a posterior approach显示文摘 | Gille O Obeid I Degrise C | 2007 | Spine2007，32，4： | 1 |
| 7 | Evaluation of spike-detection algorithms fora brain-machine interface application 显示文摘 | OBEID 1 WOLF P D | 2004 | IEEE Transactions on Biomedical Engineering2004，51，6： | 1 |
| 8 | Incidental duroto- my during spine surgery:incidence, management and com- plications : a retrospective review 显示文摘 | Guerin P E1 Fegoun AB Obeid I | 2012 | Injury2012，43，4： | 1 |
| 9 | Hyperhomocysteinemia and response of methionine cycle intermediates to vitamin treatment in renal patients 显示文摘 | Herrmann W Obeid R | 2005 | Clin Chem Lab Med2005，43，10： | 1 |
| 10 | A muhichannel telemetry system for single unit neural recordings 显示文摘 | Obeid I | 2004 | Journal of Neuroscience Methods2004，4，5： | 1 |
| 11 | Protein kinase C isoenzymes:Regulation and function显示文摘 | Blobe C C Stribling S Obeid LM | 1996 | Cancer Surveys1996，27，： | 1 |
| 12 | Improved vascular endothelial function after oral B vitamin:an effect mediated through reduced concentrations of free homocysteine显示文摘 | UELAND P M OBEID O A | 2000 | Circulation2000，102，： | 1 |
| 13 | Yeast sphingolipids:metabolism and biology显示文摘 | Lina M Obeid Yasuo Okamoto | 2002 | Biochimica et Biophysica Acts2002，1585，： | 1 |
| 14 | Ectocalreticulin in immunogenic chemotherapy显示文摘 | Obeid M Tesniere A Panaretakis T | 2007 | Immunol Rev2007，220，： | 1 |
| 15 | The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind 显示文摘 | Hannun Y A Obeid L M | 2002 | Biol Chem2002，277，25： | 1 |
| 16 | Effects of smoking on periosontal health: a review显示文摘 | Obeid P Berey P | 2000 | Adv Ther2000，17，5： | 1 |
| 17 | Physiological increments in plasma homocysteine inducevascular endothelial dysfunction in normal human subjects显示文摘 | Chambers JC Obeid OA | | 0，，12： | 1 |
| 18 | Hyperhomocysteinemia: a critical review of old and new aspects显示文摘 | Herrmann W Herrmann M Obeid R | 2007 | Curt Drug Metab2007，8，： | 1 |
| 19 | The Ceramide-centric universe of lipid-mediated cell regulation:stress encounters of the lipid kind显示文摘 | OBEID L M | 2002 | J Biol Chem2002，277，25： | 1 |
| 20 | Calreticulin exposure dictates the immunogenicity of cancer cell death显示文摘 | Obeid M Tesniere A Ghiringhelli F Fimia G M Apetoh L Perfettini J L | 2007 | Nat Med2007，13，： | 1 |
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