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| 1 | Type 2 diabetes after gestational diabetes: The influence of changing diagnostic criteria显示文摘A previous diagnosis of gestational diabetes(GDM)carries a lifetime risk of progression to type 2 diabetes of up to 60%.Identification of those women at higher risk of progression to diabetes allows the timely introduction of measures to delay or prevent diabetes onset.However,there is a large degree of variability in the literature with regard to the proportion of women with a history of GDM who go on to develop diabetes.Heterogeneity between cohorts with regard to diagnostic criteria used,duration of follow-up,and the characteristics of the study population limit the ability to make meaningful comparisons across studies.As the new International Association for Diabetes in Pregnancy Study Group criteria are increasingly adopted worldwide,the prevalence of GDM is set to increase by two-to three-fold.Here,we review the literature to examine the evolution of diagnostic criteria for GDM,the implications of changing criteria on the proportion of women with previous GDM progressing to diabetes,and how the use of different diagnostic criteria may influence the development of appropriate follow-up strategies. | Eoin Noctor Fidelma P Dunne | 2015 | World Journal of Diabetes2015，6，2： | 14 |
| 2 | H2O2-Activated Up-Regulation of Glutathione in Arabidopsis Involves Induction of Genes Encoding Enzymes Involved in Cysteine Synthesis in the Chloroplast显示文摘谷胱甘肽在对 H2O2 的反应是在细胞的氧化还原作用动态平衡并且,因此的一个关键播放器,但是调整激活氧化的谷胱甘肽合成的因素仍然是不清楚的。我们在有条件的 Arabidopsis 过氧化氢酶缺乏的异种(cat2 ) 调查了导致 H2O2 的谷胱甘肽合成。植物为 5 在提高的 CO2 从种子被种 ? 星期,然后处于短天或长天的条件转了到空气。处于任何条件在提高的 CO2 或野类型的植物比作 cat2,到在两个光周期的空气的 cat2 的转移在小时以内引起了叶谷胱甘肽水池的可测量的氧化。氧化在随后的天继续并且被谷胱甘肽的累积伴随。这效果在在短天内转移到空气的 cat2 是更强壮的,并且没被连接到可引出的活动或涉及谷胱甘肽合成的承诺的小径的抄本编码酶的可估计的增加。相反,它被丝氨酸, O-acetylserine,和半胱氨酸的增加伴随。在代谢物的这些变化被编码腺苷 phosphosulfate reductase (4 月) 的基因的正式就职伴随,特别地, APR3,以及编码 chloroplastic 的特定的丝氨酸 acetyltransferase 基因(SAT2.1 ) 坐了。标记这些基因的正式就职仅仅在处于短天的条件转移到空气的 cat2 被观察,在半胱氨酸和谷胱甘肽累积是很戏剧的的地方。不同于另外的容纳的基因,它在 cat2 显示出可以忽略的正式就职,相对许多 4 月和 SAT2.1 抄本密切为 H2O2 发信号与标记抄本被相关。一起,数据在谷胱甘肽合成的导致氧化剂的起来规定加重半胱氨酸合成的重要性并且建议叶绿体在这些情形下面做重要贡献到半胱氨酸生产。 | Guillaume Queval Dorothée Thominet Hélène Vanacker Myroslawa Miginiac-Maslow Bertrand Gakière Graham Noctor | 2009 | Molecular Plant2009，2，2： | 10 |
| 3 | Ascorbate and glutathione: keeping active oxygen under control 显示文摘 | Noctor G Foyer C H | 1998 | Annu Rev Plant Physiol Plant Mol Biol1998，49，： | 1 |
| 4 | Stage of develop-ment is an important determinant in the effect of nitrate onphotoassimilate (13C) partitioning in chicory (Cichorium in-tybus) 显示文摘 | AmezianeR Deleens E Noctor G | 1997 | Journal of Experimental Botany1997，48，： | 1 |
| 5 | Asorbate and glutathione: keeping active oxygen under control显示文摘 | Noctor G Foyer CH | 1998 | Annu Rev Plant Physiol Plant Mol Biol1998，49，： | 1 |
| 6 | Redox sensing and signaling associated with reactive oxygen in chloroplasts,peroxisomes and mitochondria显示文摘 | Foyer C H Noctor G | 2003 | Physiol Plant2003，119，： | 1 |
| 7 | Redox homeostasis and antioxidant signaling a metabolic interface between stress perception and physiological responses显示文摘 | Foyer C H Noctor G | 2005 | Plant Cell2005，17，7： | 1 |
| 8 | Redox homeostasis and antioxidant signaling:A metabolic interface between stress perception and physiological responses 显示文摘 | Foyer C H Noctor G | 2005 | Plant Cell2005，17，7： | 1 |
| 9 | Oxygen processing in photosynthesis regulation and signalling 显示文摘 | FOYER C H NOCTOR G | 2000 | New Phytol2000，146，： | 1 |
| 10 | NAD(P) synthesis and pyridine nucletide cycling in plants and their potential importance in stress conditions显示文摘 | Noctor G Queval G Gakiere B | 2006 | Journal of Experimental Botany2006，57，： | 1 |
| 11 | Ascorbate and glutathione: keeping active oxygen under control显示文摘 | Noctor G Foyer CH | 1998 | Annu Rev Plant Physiol Plant Mol Biol1998，49，： | 1 |
| 12 | Ascorbate and glutath ione : Keep ineactive oxygen under control显示文摘 | Noctor G Eover C H | 1998 | Annu Rev Plant Physiol Plant Mol Biol1998，49，1： | 1 |
| 13 | Oxidant and antioxidant signal- ling in plants:A re-evaluation of the concept of oxida- tive stress in a physiological context显示文摘 | Foyer C H Noctor G | 2005 | Plant Cell Environment2005，28，8： | 1 |
| 14 | Glutathione in plants: an integrated overview显示文摘 | NOCTOR G MHAMDI A CHAOUCH S | 2012 | Plant Cell and Environment2012，35，： | 1 |
| 15 | Ascorbate and glutathione:keeping active oxygen under control显示文摘 | NOCTOR G FOYER C H | 1998 | Annual Review of Plant Physiology and Plant Molecular Biology1998，49，： | 1 |
| 16 | Glutathione,biosynthesis,metabolism and relationship to stress tolerance explored in transformed plants显示文摘 | Noctor G Arisi A C Jouanin L | 1998 | J Exp Bot1998，49，： | 1 |
| 17 | Leaf mitochondria modulate whole cell redox homeostasis,set antioxidant capacity,and determine stress resistance through altered signaling and diurnal regulation显示文摘 | Dutilleul C Garmier M Noctor G | 2003 | Plant Cell2003，15，5： | 1 |
| 18 | Ascorbate and glutathione:Keeping active oxygen under control显示文摘 | Noctor G Foyer C H | 1998 | Annu rev Plant Physiol Plant Mol Biol1998，49，： | 1 |
| 19 | Ascorbate and glutathione: keeping active oxygen under control显示文摘 | Noctor G Foyer C H | 1998 | Plant Biology1998，49，6： | 1 |
| 20 | Oxidant and antioxidant signalling in plants: a re-evaluation of the concept of oxidative stress in a physiological context显示文摘 | FOYER C NOCTOR G | 2005 | Plant Cell and Environment2005，28，： | 1 |
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