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| 1 | Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma.显示文摘 | Abrey LE Batchelor TT Ferreri A J Gospodarowicz M Pulczynski EJ Zucca E Smith JR Korfel A Soussain C DeAngelis LM Neuwelt EA O′Neill BP Thiel E Shenkier T Graus F van den Bent M Seymour JF Poortmans P Armitage JO Cavalli F | 2005 | 中国神经肿瘤杂志2005，3，3： | 53 |
| 2 | Conversion from prolonged intravenous fentanyl infusion to enteral methadone in critically ill children显示文摘AIM To describe our institutional experience with conversion from intravenous(IV) fentanyl infusion directly to enteral methadone and occurrence of withdrawal in critically ill mechanically ventilated children exposed to prolonged sedation and analgesia.METHODS With Institutional Review Board approval,we retrospectively studied consecutively admitted invasively mechanically ventilated children(0-18 years) sedated with IV fentanyl infusion > 5 d and subsequently converted directly to enteral methadone.Data were obtained onsubject demographics,illness severity,daily IV fentanyl and enteral methadone dosing,time to complete conversion,withdrawal scores(WAT-1),pain scores,and need for rescue opioids.Patients were classified as rapid conversion group(RCG) if completely converted ≤ 48 h and slow conversion group(SCG) if completely converted in > 48 h.Primary outcome was difference in WAT-1 scores at 7 d.Secondary outcomes included differences in overall pain scores,and differences in daily rescue opioids.RESULTS Compared to SCG(n = 21),RCG(n = 21) had lower median WAT-1 scores at 7 d(2.5 vs 5,P = 0.027).Additionally,RCG had lower overall median pain scores(3 vs 6,P = 0.007),and required less median daily rescue opioids(3 vs 12,P = 0.003) than SCG.The starting daily median methadone dose was 2.3 times the daily median fentanyl dose in the RCG,compared to 1.1 times in the SCG(P = 0.049).CONCLUSION We observed wide variation in conversion from IV fentanyl infusion directly to enteral methadone and variability in withdrawal in critically ill mechanically ventilated children exposed to prolonged sedation.In those children who converted successfully from IV fentanyl infusion to enteral methadone within a period of 48 h,a methadone:fentanyl dose conversion ratio of approximately 2.5:1 was associated with less withdrawal and reduced need for rescue opioids. | Vijay Srinivasan Daniel Pung Sean P O'Neill | 2017 | World Journal of Clinical Pediatrics2017，6，2： | 3 |
| 3 | C-reactive protein and radiographic findings of lower respiratory tract infection in infants显示文摘AIM To evaluate the association between C-reactive protein(CRP) and radiological evidence of lower respiratory tract infection(LRTI) in infants.METHODS All patients aged less than 4 years who presented with suspected lower respiratory tract infection,who received a peri-presentation chest radiograph and CRP blood measurement over an 18-mo period were included in the study.Age,gender,source of referral,CRP,white cell count,neutrophil count along with the patients' symptoms and radiologist's report were recorded.RESULTS Three hundred and eleven patients met the inclusioncriteria.Abnormal chest radiographs were more common in patients with elevated CRP levels(P < 0.01).Radiologic signs of LRTI were identified in 73.7% of chest radiographs when a patient had a CRP level between 50-99 mg/L.CRP levels were a better predictor of positive chest radiograph findings for those aged greater than I year compared to those 1 year or less.CONCLUSION CRP may be used in patients with suspected LRTI diagnosis to select those who are likely to have positive findings on chest radiograph,thus reducing unnecessary chest radiographs. | Maria Twomey Hannah Fleming Fiachra Moloney Kevin P Murphy Lee Crush Siobhan B O’Neill Oisin Flanagan Karl James Conor Bogue Owen J O’Connor Michael M Maher | 2017 | World Journal of Radiology2017，9，4： | 2 |
| 4 | Implantation potential and fetal viability of mouse embryos cultured in media supplemented with platelet activating factor 显示文摘 | Ryan J P Spinks N R O'Neill C | 1990 | J Reprod Fertil1990，89，： | 2 |
| 5 | Rhamnogalacturonan II: structure and function of a borate cross-linked cell wall pectic pelysaccharide显示文摘 | O'Neill M A Ishii T Albersheim P | 2004 | Armu Rev Plant Biol2004，55，： | 1 |
| 6 | Concrete deterioration from physical attack by salts 显示文摘 | Haynes H O’Neill R Mehta P K | 1996 | Concr Int1996，18，1： | 1 |
| 7 | Chemical aspects of clustered DNA damage induction by ionising radiation显示文摘 | Lomax ME Gulston MK and O'Neill P | 2002 | Radiat Prot Dosim2002，99，14： | 1 |
| 8 | Rapid purification of staphylococcal enterotoxin B by high-pressure liquid chromatography显示文摘 | Strickler M P Neill R J Stone M J | 1989 | J Clin Microbiol1989，27，5： | 1 |
| 9 | Virtues and Vices of Quartic Time-Frequency Distributions 显示文摘 | O'Neill J C Flandrin P | 2000 | IEEE Trans on Signal Processing2000，48，9： | 1 |
| 10 | SLC2A9 is a high-capacity urate transporter in humans 显示文摘 | Caulfield M J Munroe P B O'Neill D | 2008 | PLoS Med2008，5，10： | 1 |
| 11 | Multi-frequency measurements of the effects of soil moisture,soil texture,and surface roughness显示文摘 | Wang J R O'Neill P E Jackson T J | 1983 | IEEE Transactions on Geoscience and Remote Sensing1983，21，1： | 1 |
| 12 | FIGO Staging system for endometrial cancer: added benefits of MR imaging 显示文摘 | Beddy P O'Neill AC Yamamoto AK | 2012 | Radiograph- ics2012，32，1： | 1 |
| 13 | The relationship between perceived stigma, disclosure patterns, support and distress in new attendees at an infertility clinic显示文摘 | Slade P Neill CO Simpson | 2007 | Human Reproduc- tion2007，22，8： | 1 |
| 14 | Dilute acid hydrolysis of ligno- cellulosic biomass显示文摘 | Lenihan P Orozco A O'Neill E | 2010 | Chemical Engineering Journal2010，156，： | 1 |
| 15 | Endogenous endophthalrnitis: 10-year experience at a tertiary referral centre 显示文摘 | Connell P P O'Neill E C Fabinyi D | 2011 | Eye ( Loud )2011，25，1： | 1 |
| 16 | The biomimetic iron-mediated degradation of arteflene (Ro-42-1611), an endoperoxide antimalarial implications for the mechanism of antimalarial activity 显示文摘 | O'Neill P M Bishop L P Sesrle N L | 1997 | Tet rahedron Lett1997，38，24： | 1 |
| 17 | Reducing methane emissions in sheep by immunization against rumen methanogens显示文摘 | Wright A D G Kennedy P O Neill C J | 2004 | Vaccine2004，22，： | 1 |
| 18 | Declining estrogen receptor-beta expression defines malignant progression of human breast neoplasia显示文摘 | Shaaban AM O'Neill PA DaviesM P | 2003 | Am J Surg Pathol2003，27，： | 1 |
| 19 | The role of basic sciences in a problembased learning curriculum显示文摘 | ONEILL P A | 2000 | Med Edu2000，34，8： | 1 |
| 20 | Somatic cell gene mutations in humans : biomarkers for genotoxicity 显示文摘 | ALBERTINI R J NICKLAS J A O'NEILL J P | 1993 | Environ Health Perspect1993，101，： | 1 |
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