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| 1 | Hepatic ischemic preconditioning increases portal vein flow in experimental liver ischemia reperfusion injury显示文摘BACKGROUND: Ischemic preconditioning(IPC) has been shown to decrease liver injury and to increase hepatic microvascular perfusion after liver ischemia reperfusion. This study aimed to evaluate the effects of IPC on hemodynamics of the portal venous system. METHODS: Thirty-two rats were randomized into two groups: IPC group and control group. The rats of the IPC group underwent IPC by 10 minutes of liver ischemia followed by 10 minutes of reperfusion before liver ischemia, and the rats of the control group were subjected to 60 minutes of partial liver ischemia. Non-ischemic lobes were resected immediately after reperfusion. The animals were studied at 4 hours and 12 hours after reperfusion. Mean arterial pressure, heart rate, portal vein flow and pressure were analyzed. Blood was collected for the determination of the levels of aspartate aminotransferase, alanine aminotransferase, calcium, lactate, pH, bicarbonate, and base excess. RESULTS: IPC increased the mean portal vein flow at 4 hours and 12 hours after reperfusion. IPC recovered 78% of the meanportal vein flow at 12 hours after reperfusion. IPC decreased the levels of aspartate aminotransferase, alanine aminotransferase and lactate, and increased the levels of ionized calcium, bicarbonate and base excess at 12 hours after reperfusion. CONCLUSIONS: This study demonstrated that IPC increases portal vein flow and enhances hepatoprotective effects in liver ischemia reperfusion. The better recovery of portal vein flow after IPC may be correlated with the lower levels of transaminases and with the better metabolic profile. | Estela RR Figueira Joel A Rocha-Filho Mauro Nakatani Marcelo FS Buto Eduardo R Tatebe Vitor O Andre Ivan Cecconello Luiz AC D'Albuquerque | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，1： | 6 |
| 2 | Chromophobe renal cell carcinoma:an immunohistochemical study of 21 Japanese cases显示文摘 | Taki A Nakatani Y Misugi K | 1999 | Mod Pathol1999，12，： | 1 |
| 3 | Phragmalin limonoids from Chukrasia tabularis 显示文摘 | NAKATANI M ABDELGALEIL S A M SAAD M M G | 2004 | Phytochemistry2004，65，20： | 1 |
| 4 | Quantitative assessment of short axis wall motion using myocardial strain rate imaging显示文摘 | Nakatani S Stugaard M Hanatani A | 2003 | Echocardiography2003，20，2： | 1 |
| 5 | Chromophobe renal cell carcinoma: An immunohistochemical study of 21 japanese cases 显示文摘 | Taki A Nakatani Y Misugi K | 1999 | Mod Pathol1999，12，3： | 1 |
| 6 | Preparation of activated carbon fibers with large specific surface area from softwood acetic acid lignin显示文摘 | Uraki Y Nakatani A Kubo S | 2001 | Journal of Wood Science2001，47，6： | 1 |
| 7 | Synthesis of Ordered Mesoporous Carbon Films, Powders and Fibers by Direct Triblock copolymer templating Method Using an Ethanol/Water System显示文摘 | Doi A Tanaka S Nakatani N | 2009 | Carbon2009，47，11： | 1 |
| 8 | Photocatalytic removal of fenitrothion in pure and natural waters by photo-Fenton reaction显示文摘 | Derbalah A S Nakatani N Sakugawa H | 2004 | Chemosphere2004，57，7： | 1 |
| 9 | Sudden difficulty in ventila- tion due to massive subcutaneous emphysema during laparoscopic cholecystectomy显示文摘 | Imai H Nakatani N Matsuda S et a l | 2005 | Masui2005，54，6： | 1 |
| 10 | Successful treatment of congenital systemic juvenile xanthogranuloma with Langerhans cell hlstiocytosis-based chemotherapy显示文摘 | Nakatani T Morimoto A Kato R | 2004 | J Pediatr Hematol Onol2004，26，6： | 1 |
| 11 | Effects of the glyphosate-resistance gene and herbicides on soybean: Field trials monitoring biological nitrogen fixation and yield显示文摘 | Hungria M Mendes I C Nakatani A S | 2014 | Field Crops Research2014，158，： | 1 |
| 12 | Synthesis of Hybrid Organic-Iorganic Materials from Interpenetrating Polymer Network Chemistry显示文摘 | Jackson C L Bauer B J Nakatani I A | 1996 | Chem Mater1996，8，： | 1 |
| 13 | Relationship between the distribution of myofibroblasts, and stellar and circular scar formation due to the contraction of square and circular wound healing 显示文摘 | Mawaki A Nakatani T Sugama J | 2007 | Anat Sci Int2007，82，3： | 1 |
| 14 | Antroxidative and antrinflammatory curcum in-related phenolics from rhizomes of Curcuma domestica显示文摘 | Masuda T Jitoe A Nakatani N | 1993 | Phytochemistry1993，32，6： | 1 |
| 15 | Multiple attack mechanism in the porcine pancreatic alpha-amylase hydrolysis of amylose and amylopectin显示文摘 | Mazur A K Nakatani H | 1993 | Arch Biochem Biophys1993，306，： | 1 |
| 16 | Linear and nonlinear optical properties of photochromic molecules and materials显示文摘 | Delaire J A Nakatani K | 2000 | Chem Rev2000，100，5： | 1 |
| 17 | Anti-oxidative and anti-inflammatory curcum in-related phenolics from rhizomes of Curcuma domestica显示文摘 | Masuda T Jitoe A Nakatani N | 1993 | Phytochemistry1993，32，6： | 1 |
| 18 | Quantitative assessment of short axis wall motion using myocardial strain rate imaging显示文摘 | Nakatani S Stugaard M Hanatani A | 2003 | Echocardiography2003，20，2： | 1 |
| 19 | Linear and nonlinear opticalproperties of photochromic molecules and materials显示文摘 | Delaire J A Nakatani K | 2000 | Chem Rev2000，100，： | 1 |
| 20 | New miscrosatel- lite markers developed from reported Ipomoea trifida se- quences and their application to sweetpotato and its re- lated wild species 显示文摘 | Hu J J Nakatani M Lalusin A G | 2004 | Scientia I-Iorticulturae2004，102，4： | 1 |
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