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| 1 | Skeletal muscle myogenesis is regulated by G protein-coupled receptor kinase 2显示文摘G 联合蛋白质的受体 kinase (GRK2 ) 2 是调整不同的膜 receptorsand 的重要 serine/threonine-kinase 细胞内部的蛋白质。在胚胎或成年苍蝇的果蝇 Gprk2 的变细导致了体的肌肉,纤维的损失,和不能飞行的 phenotype.In 的有缺点的区别脊椎动物, GRK2 hemizygous 老鼠少些,但是更包含了 hypertrophied 骨胳的肌肉纤维比野类型的 littermates.In C2C12 myoblasts , GRK2 kinase缺乏的异种( K220R )的 overexpression 引起了房间 intoimmature myotubes 的早熟的区别,它在尺寸是更宽的并且包含了更多的熔化原子核,当时 GRK2 overexpression b 熔化事件由提高的 GRK2 层次支持了的损害 differentiationand 少数被 p38MAPK 异种概括,它能由 GRK2 模仿 p38MAPK 的 theinhibitory phosphorylation,而在表示 GRK2 观察的弄钝的区别面对 p38MAPK 小径的一个组成地活跃的在上游的激发器克隆 wasrescued。这些结果建议 thatbalanced GRK2 功能为一个及时、完全的 myogenic 过程是必要的。 | Lucia Garcia-Guerra Rocio Vila-Bedmar Marta Carrasco-Rando Marta Cruces-Sande Mercedes Martin Ana Ruiz-Gomez Mar Ruiz-Gomez Margarita Lorenzo Sonia Fernandez-Veledo Federico Mayor Jr. Cristina Murga Iria Nieto-Vazquez | 2014 | Journal of Molecular Cell Biology2014，8，4： | 3 |
| 2 | Biofilm structural heterogeneity visualized by three microscopic methuds显示文摘 | Stewart PS Murga R Srinivasan R | 1995 | Water Res1995，29，8： | 1 |
| 3 | Microvascular angina pectoris in hypertensive patients with left ventricular hypertrophy and diagnostic value of exercise thallium-201 scintigraphy 显示文摘 | lriarte M Casc R Murga N | 1995 | Am J Cardiol1995，75，2： | 1 |
| 4 | Mechanisms of regu- lation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease 显示文摘 | Penela P Murga C Ribas C | 2006 | Cardiovasc Res2006，69，1： | 1 |
| 5 | Supercritical fluid extraction and fractionation of different preprocessed rosemary plants显示文摘 | Ibanez E Oca A Murga G De | 1999 | J Agric Food Chem1999，47，： | 1 |
| 6 | Microvascular angina pectoris in hypertensive patients with left ventricular hypertrophy and diagnostic value of exercise thallium-201 scintigraphy显示文摘 | Iriarte M Caso R Murga N | 1995 | Am J Cardiol1995，75，5： | 1 |
| 7 | Influence of growth temperature on cryotolerance and lipid composition of lactobacillus acidophilus显示文摘 | FERNANDEZ MURGA M L CABRERA G M FONT DE VALDEZ G | 2000 | Journal of Applied Microbiology2000，88，2： | 1 |
| 8 | Genetic Algorithms for the Traveling Salesman Problem: a Review of Representations and Operators显示文摘 | Larranaga P Kuijpers C M H Murga R H et al | 1999 | Artificial Intelligence Review1999，13，2： | 1 |
| 9 | PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells显示文摘 | Choi Y Zhang J Murga C | 2002 | Oncogene2002，21，34： | 1 |
| 10 | The G protein-coupled receptor kinase (GRK) interactorne , role of GRKs in GPCR regulation and signaling 显示文摘 | Ribas C Penela P Murga C | 2007 | Biochim Biophys Acta2007，1768，4： | 1 |
| 11 | Genetic algorithms for the traveling salesman problem: a review of representations and operators 显示文摘 | LARRANAGA P KUIJPERS C M H MURGA R H | 1999 | Artificial Intelligence Review1999，13，2： | 1 |
| 12 | Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function 显示文摘 | Williams CK Li JL Murga M | 2006 | Blood2006，107，3： | 1 |
| 13 | Up-regulation of the Notch lig-and Delta-like4inhibits VEGF-induced endothelial cell function显示文摘 | Williams CK Li JL Murga M | 2006 | Blood2006，107，3： | 1 |
| 14 | Mutation of E2F2 in mice causes enhanced T lymphocyte proliferation, leading to the development of autoimmunity显示文摘 | Murga M Fernandez-Capetillo O Field SJ | 2001 | Immunity2001，15，6： | 1 |
| 15 | Auto-catalyzed and ion-exchange-resin catalyzed esterification kinetics of lactic acid with methanol显示文摘 | SANZ M T MURGA R CABEZAS S COCA J L | 2002 | Ind Eng Chem Res2002，41，2： | 1 |
| 16 | The complex G pro- tein-coupled receptor kinase 2 (GRK2) interactome un- veils new physiopathological targets 显示文摘 | Penela P Murga C Ribas C | 2010 | Br J Pharmacol2010，160，4： | 1 |
| 17 | The developing intestinal mi- crobiome and its relationship to health and disease in the neonate显示文摘 | Murgas Torrazza R Neu J | 2011 | J Perinatol2011，31，1： | 1 |
| 18 | Racl and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaB 显示文摘 | Murga C Zohar M Teramoto H | 2002 | Oncogene2002，21，2： | 1 |
| 19 | Influence of the incubation temperature on the autolytie activity of Lactobacillus acidophilus显示文摘 | FERNANDEZ MURGA M L | 1995 | Journal of Applied Bacteriology1995，78，： | 1 |
| 20 | The effect of clonidine on intraoperative requirements of fentanyl during combined epidural/general anaesthesia显示文摘 | MURGA G SAMSO E VALLES J | 1994 | Anaesthesia1994，49，： | 1 |
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