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| 1 | How does a real-world child psychiatric clinic diagnose and treat attention deficit hyperactivity disorder?显示文摘AIM: To investigate child and adolescent psychiatrists'(CAPs) attention deficit hyperactivity disorder(ADHD) and oppositional defiant disorder(ODD) diagnoses and treatments in real-world clinical practice. METHODS: The medical records of 69 ADHD children(mean age = 9.5 years), newly referred to the ADHD clinic, were reviewed for their scores of parent- and teacher-reported Vanderbilt ADHD Diagnostic Rating Scales(VADRSs), CAPs' diagnoses of ADHD and ODD, and CAPs' treatment recommendations. Among 63 ADHD subjects who completed both parent and teacher VADRSs, we examined the agreement of the parent and teacher VADRSs. We also examined the concurrent validity of CAPs' ODD diagnoses against the results from the VADRSs. In addition, we compared CAPs' treatment recommendations against established ADHD and ODD guidelines.RESULTS: Among 63 ADHD subjects, the majority of the subjects(92%) met full ADHD diagnostic criteria at least in one setting(parent or teacher) on the VADRSs. Nearly half of the patients met full ADHD diagnostic criteria in two settings(parent and teacher). Relatively low agreement between the parent and teacher VADRSs were found(95%CI:-0.33 to 0.14). For 29 children who scored positive for ODD on the rating scales, CAPs confirmed the ODD diagnosis in only 12 of these casepositives, which is considered as a fair agreement between CAPs and VADRSs(95%CI: 0.10-0.53). For 27 children with no ODD diagnosis made by either CAP or VADRS, more than half of them were recommended for medication only. In contrast, where CAPs made the diagnosis of ODD, or where the parent or teacher VADRS was positive for ODD, almost all of the patients received recommendations for medication and behavior therapy.CONCLUSION: CAPs' ADHD diagnoses have strong concurrent validity against valid rating scales, but ADHD's most common comorbid condition- ODD- may be underrecognized. | Kumi Yuki Jyoti Bhagia David Mrazek Peter S Jensen | 2016 | World Journal of Psychiatry2016，6，1： | 2 |
| 2 | Comparative DNA analysis across diverse genomes显示文摘 | Karlin S Campbell AM Mrazek J | 1998 | Annu Rev Genetics1998，32，： | 1 |
| 3 | Psyehosocial interventions and cancer patients: psychological and immune responses may depend on cancer type显示文摘 | Glas R Reavley N Mrazek L | 2001 | Med Hypotheses2001，56，4： | 1 |
| 4 | Pigment epithelium-derived factor supports normal development of photoreceptor neurons and opsin expression after retinal pigment epithelium removal 显示文摘 | Jablonski MM Tombran-Tink J Mrazek DA Iannaccone A | 2000 | J Neurosci2000，20，19： | 1 |
| 5 | Pigment epithelium-derived factor protects cultured retinal neurons against hydrogen peroxide-induced cell death显示文摘 | Cao W Tombran-Tink J Chen W Mrazek D Elias R McGinnis JF | 1999 | J Neurosci Res1999，57，6： | 1 |
| 6 | Diversity of insect intes- tinal microflora 显示文摘 | Mrazek J Strosova L FliegerovO K | 2008 | Folia Microbiologica2008，53，3： | 1 |
| 7 | Invivo protection of photoreceptors from light damage by pigment epithelium-derived factor 显示文摘 | Cao W Tombran-Tink J Elias R Sezate S Mrazek D McGinnis JF | 2001 | Invest Ophthalmol Vis Sci2001，42，7： | 1 |
| 8 | Regulating pharmace- utical markets: improving efficiency and controlling costs in the UK显示文摘 | Walley T Mrazek M Mossialos E | 2005 | International Journal of Health Planning and Management2005，20，4： | 1 |
| 9 | Pigment epithelium-derived factor protects cultured retinal neurons against hydrogen peroxide-induced cell death 显示文摘 | Cao W Tombran-Tink J Chen W Mrazek D Elias R McGinnis JF | 1999 | J Neurosci Res1999，57，6： | 1 |
| 10 | Depression,apolipoprotein E genotype,and the incidence of mild cognitive impairment:a prospective cohort study显示文摘 | Geda YE Knopman DS Mrazek DA | 2006 | Arch Neurol2006，63，3： | 1 |
| 11 | Design, synthesis, and characterization of novel apigenin analogues that suppress pancre- atic stcllate cell proliferation in vitro and associated pancreatic fibrosis in vivo显示文摘 | CHEN H MRAZEK AA WANG X | 2014 | Bioorganic & Medicinal Chemistry2014，22，13： | 1 |
| 12 | Depression, apolipoprotein E genotype, and the incidence of mild cognitive im- pairment: a prospective cohort study 显示文摘 | Geda YE Knopman DS Mrazek DA | 2006 | Arch Neurol2006，63，3： | 1 |
| 13 | Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) induces the expression of the cellular microRNA miRNA-146a显示文摘 | Motsch N Pfuhl T Mrazek J | 2007 | RNA Biol2007，4，3： | 1 |
| 14 | What drives codon,choices in human genes显示文摘 | Karlin S Mrazek J | 1996 | J Mol Biol1996，262，： | 1 |
| 15 | Comparative approaches to pharmaceutical price regulation in the european union显示文摘 | Mrazek MF | 2002 | Croatian Medical Journal2002，43，4： | 1 |
| 16 | Distribution of 22 cytokine gene polymorphisms in the healthy Czech population 显示文摘 | Kubistova Z Mrazek F Tudos Z | 2006 | In J Immunogenet2006，33，4： | 1 |
| 17 | Epstein-barr virus-induced expression of a novel human vault RNA显示文摘 | Nandy C Mrazek J Stoiber H | 2009 | J Mol Biol2009，388，4： | 1 |
| 18 | The MCP- 1 -2518 (A/G) single nucleotide polymorphism is associated with ischemic heart disease and myocardial infarction in men in the Slovak population 显示文摘 | Bucova M Lietava J Mrazek F | 2009 | Bratisl Lek Listv2009，110，7： | 1 |
| 19 | Selection of optimal stopping time for nonlinear diffusion filtering显示文摘 | Mrazek P and Navara M | 2003 | International Journal of Computer Vision2003，52，18： | 1 |
| 20 | Investigation of the sensitivity of PCS fibers to changes of light absorption coefficient of the cladding:Photonics,Devices,and Systems Ⅱ显示文摘 | Chomat Miroslav Mrazek Jan Matejec Vlastimil | 2003 | Proceedings of the SPIE2003，5036，： | 1 |
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