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| 1 | Feasibility and safety of cryoballoon ablation for atrial fibrillation inpatients with congenital heart disease显示文摘BACKGROUND The prevalence of atrial fibrillation (AF) is on the rise in the aging population with congenital heart disease (CHD). A few case series have described the feasibility and early outcomes associated with radiofrequency catheter ablation of AF centered on electrically isolating pulmonary veins (PV) in patients with CHD. In contrast, cryoballoon ablation has not previously been studied in this patient population despite its theoretical advantages, which include a favorable safety profile and shorter procedural time. AIM To assess the safety and feasibility of cryoballoon ablation for AF in an initial cohort of patients with CHD. METHODS The study population consisted of consecutive patients with CHD and cryoballoon ablation for AF at the Montreal Heart Institute between December 2012 and June 2017. Procedural complications, acute success, and 1-year freedom from recurrent AF after a single procedure with or without antiarrhythmic drugs were assessed. Procedures were performed under conscious sedation. Left atrial access was obtained via a single transseptal puncture or through an existing atrial septal defect (ASD). Cryoballoon occlusion was assessed by distal injection of 50% diluted contrast into the pulmonary vein. At least one 240-second cryothermal application was performed upon obtaining complete pulmonary vein occlusion. Following ablation, patients were routinely followed at outpatient visits at 1, 3, 6, and 12 mo, and then annually. RESULTS Ten patients, median age 57.9 (interquartile range 48.2-61.7) years, 60% female, met inclusion criteria and were followed for 2.8 (interquartile range 1.4-4.5) years.Two had moderately complex CHD (sinus venosus ASD with partial anomalous pulmonary venous return;aortic coarctation with a persistent left superior vena cava), with the remainder having simple defects. AF was paroxysmal in 8 (80.0%) and persistent in 2 (20.0%) patients. The pulmonary vein anatomy was normal in 6 (60.0%) patients. Four had left common PV (n = 3) and/or 3 right PV (n = 2). Electrical pulmonary vein isolation (PVI) was acutely successful in all. One patient had transient phrenic nerve palsy that recovered during the intervention. No major complication occurred. One year after a single ablation procedure, 6 (60%) patients remained free from AF. One patient with recurrent AF had recovered pulmonary vein conduction and underwent a second PVI procedure. A second patient had ablation of an extra-pulmonary vein trigger for AF. CONCLUSION Cryoballoon ablation for AF is feasible and safe in patients with simple and moderate forms of CHD, with an excellent acute success rate and modest 1-year freedom from recurrent AF. | Sylvia Abadir Victor Waldmann Katia Dyrda Mikael Laredo Blandine Mondésert Marc Dubuc Paul Khairy | 2019 | World Journal of Cardiology2019，11，5： | 3 |
| 2 | 胸前植入埋藏式心律转复除颤器——一种简易的植入方法显示文摘以往的开胸植入ICD系统手术操作繁琐,并发症多,非开胸植入ICD系统的应用降低了手术相关的并发症.本文介绍了新一代的经静脉胸前植入ICD.25例恶性室性心律失常患者应用了第三代非开胸植入ICD系统,其中18例为单极除颤系统.25例患者中24例(96%)除颤阀值≤24焦耳,而成功地植入了ICD.另一例由于阈值偏高而改用了开胸植人.所有患者的ICD均埋藏于患者的左胸前的皮下组织或胸大肌下的束袋中,除一例患者术后发生束袋血肿外,无明显并发症.经静脉胸前植入ICD手术切口少,操作简单,并发症较少,临床应用效果满意,将逐渐取代开胸植入系统. | 华伟 Jitu Vohra Harry Mond | 1998 | 中国心血管杂志1998，3，6： | 3 |
| 3 | Hydrogen Gas Filling into an Actual Tank at High Pressure and Optimization of Its Thermal Characteristics显示文摘Gas with high pressure is widely used at present as fuel storage mode for different hydrogen vehicles. Differenttypes of materials are used for constructing these hydrogen pressure vessels. An aluminum lined vessel and typicallycarbon fiber reinforced plastic (CFRP) materials are commercially used in hydrogen vessels. An aluminumlined vessel is easy to construct and posses high thermal conductivity compared to other commercially availablevessels. However, compared to CFRP lined vessel, it has low strength capacity and safety factors. Therefore,nowadays, CFRP lined vessels are becoming more popular in hydrogen vehicles. Moreover, CFRP lined vesselhas an advantage of light weight. CFRP, although, has many desirable properties in reducing the weight and inincreasing the strength, it is also necessary to keep the material temperature below 85 ℃ for maintaining stringentsafety requirements. While filling process occurs, the temperature can be exceeded due to the compression worksof the gas flow. Therefore, it is very important to optimize the hydrogen filling system to avoid the crossing of thecritical limit of the temperature rise. Computer-aided simulation has been conducted to characterize the hydrogenfilling to optimize the technique. Three types of hydrogen vessels with different volumes have been analyzed foroptimizing the charging characteristics of hydrogen to test vessels. Gas temperatures are measured inside representativevessels in the supply reservoirs (H2 storages) and at the inlet to the test tank during filling. | Md.Tawhidul Islam Khan Masanori Monde Toshiaki Setoguchi | 2009 | Journal of Thermal Science2009，18，3： | 2 |
| 4 | Critical Heat Flux of Natural Circulation Boiling in a Vertical Tube (Effect of Oscillation and Circulation on CHF 显示文摘 | Monde M Mitsutake Y | 2002 | Int J Heat Mass Transfer2002，45，： | 2 |
| 5 | Small increases in extravascular lungwater are accu- rately detected by transpulmonary thermodilution 显示文摘 | Fern Adez - Mond jar E Rivera - Fern Adez R Garc a - Del- gadoM | 2005 | J Trauma2005，59，： | 1 |
| 6 | Vacuum electronics for the 21st Century 显示文摘 | Abram R H Mondeli A A Parker R K | 2001 | IEEE Microwave Magazine2001，2，3： | 1 |
| 7 | Influence of membrane fluidity on haman immunodeficiency virus type 1 entry显示文摘 | Harada S Yusa K Monde K | 2005 | Bio- chem Biophys Res Commun2005，329，2： | 1 |
| 8 | The right ventricular outflow tract: a comparative study of septal, anterior wall, and free wall pacing显示文摘 | Hillock RJ Stevenson IH Mond HG | 2007 | Pacing Clin Eleetrophysiol2007，30，8： | 1 |
| 9 | The right ventricular outflow tract: a comparative study of septal, anterior wall, and free wall pacing 显示文摘 | Hillock R J Stevenson I H Mond H G | 2007 | Pacing Clin Electrophysiol2007，30，8： | 1 |
| 10 | Processing and degradation of chloroplast mRNA 显示文摘 | MONDE R A SCHUSTER G STERN D B | 2000 | Biochimie2000，82，67： | 1 |
| 11 | Necessary and Sufficient Conditions in Constrainted Optimization 显示文摘 | HANSON M A MOND M | 1987 | Mathematical Pro- gramming1987，37，2： | 1 |
| 12 | Early diagnosis of spinal metastasis by MR studies显示文摘 | Colman LK Porter BA Red mond J | 1998 | TCAR1998，12，： | 1 |
| 13 | Pre-invex Functions in Multiple Objective Optimization显示文摘 | Wer T Mond B | 1988 | J Math Anal Appl1988，136，1： | 1 |
| 14 | Critical heat flux during natural convective boiling on uniformly heated vertical tubes submerged in saturated liquid 显示文摘 | Monde M MIhara S Yamaji K | 1990 | JSME1990，56，531： | 1 |
| 15 | Improved pharmacokinetics and reduced antibody reactivity of lysostaphin conjugated to polyethylene glycol 显示文摘 | Walsh S Shah A Mond J | 2003 | Antimicrob Agents Chemother2003，47，2： | 1 |
| 16 | Preinvex functions in multiple-objective optimization显示文摘 | Weir T Mond B | 1988 | J Math Anal Appl1988，136，1： | 1 |
| 17 | Preinvex functions in multiple objective optimization 显示文摘 | WEIR T MOND B | 1988 | J Math Anal Appl1988，136，： | 1 |
| 18 | Preinvex functions in multiple objective optimization显示文摘 | WEIR T MOND B | 1988 | J Math Anal Appl1988，136，： | 1 |
| 19 | 显示文摘 | Mond L | | Journal of the Chemical Society0，，2： | 1 |
| 20 | On Generalized Convex Mathematical Programming 显示文摘 | Jeyakumar V Mond B | 1992 | Journal of Australian Mathematical Society: Series B1992，34，1： | 1 |
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