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| 1 | Successful treatment of conversion chemotherapy for initially unresectable synchronous colorectal liver metastasis显示文摘A 72-year-old woman with a sigmoid colon cancer and a synchronous colorectal liver metastasis(CRLM),which involved the right hepatic vein(RHV)and the inferior vena cava(IVC),was referred to our hospital.The metastatic lesion was diagnosed as initially unresectable because of its invasion into the confluence of the RHV and IVC.After she had undergone laparoscopic sigmoidectomy for the original tumor,she consequently had 3 courses of modified 5-fluorouracil,leucovorin,and oxaliplatin(m FOLFOX6)plus cetuximab.Computed tomography revealed a partial response,and the confluence of the RHV and IVC got free from cancer invasion.After 3 additional courses of m FOLFOX6 plus cetuximab,preoperative percutaneous transhepatic portal vein embolization(PTPE)was performed to secure the future remnant liver volume.Finally,a right hemihepatectomy was performed.The postoperative course was uneventful.The patient was discharged from the hospital on postoperative day 13.She had neither local recurrence nor distant metastasis 18 mo after the last surgical intervention.This multidisciplinary strategy,consisting of conversion chemotherapy using FOLFOX plus cetuximab and PTPE,could contribute in facilitating curative hepatic resection for initially unresectable CRLM. | Kenta Baba Akihiko Oshita Mohei Kohyama Satoshi Inoue Yuta Kuroo Takuro Yamaguchi Hiroyuki Nakamura Yoichi Sugiyama Tatsuya Tazaki Masaru Sasaki Yuji Imamura Yutaka Daimaru Hideki Ohdan Atsushi Nakamitsu | 2015 | World Journal of Gastroenterology2015，21，6： | 10 |
| 2 | Current treatment strategies and future perspectives for gastrointestinal stromal tumors显示文摘Gastrointestinal stromal tumors(GISTs)are mesenchymal tumors that originate from the gastrointestinal tract,mostly from the stomach.GISTs are derived from the myenteric interstitial cells of Cajal and are caused by several mutations in the c-kit and platelet-derived growth factor receptor genes.Clinically,GISTs are detected by endoscopic and imaging findings and are diagnosed by immunostaining.Surgery is the first line of treatment,and if the tumor is relatively small,minimally invasive surgery such as laparoscopy is performed.In recent years,neoadjuvant therapy has been administered to patients with GISTs that are suspected of having a large size or infiltration to other organs.Postoperative adjuvant imatinib is the standard therapy for high-risk GISTs.It is important to assess the risk of recurrence after GIST resection.However,the effect of tyrosine kinase inhibitor use will vary by the mutation of c-kit genes and the site of mutation.Furthermore,information regarding gene mutation is indispensable when considering the treatment policy for recurrent GISTs.This article reviews the clinicopathological characteristics of GISTs along with the minimally invasive and multidisciplinary treatment options available for these tumors.The future perspectives for diagnostic and treatment approaches for these tumors have also been discussed. | Yoichi Sugiyama Masaru Sasaki Mohei Kouyama Tatsuya Tazaki Shinya Takahashi Atsushi Nakamitsu | 2022 | World Journal of Gastrointestinal Pathophysiology2022，13，1： | 5 |
| 3 | Cardiac and pericardial tumors:A potential application of positron emission tomography-magnetic resonance imaging显示文摘Cardiac and pericardial masses may be neoplastic, benign and malignant, non-neoplastic such as thrombus or simple pericardial cysts, or normal variants cardiac structure can also be a diagnostic challenge. Currently, there are several imaging modalities for diagnosis of cardiac masses; each technique has its inherent advantages and disadvantages. Echocardiography, is typically the initial test utilizes in such cases, Echocardiography is considered the test of choice for evaluation and detection of cardiac mass, it is widely available, portable, with no ionizing radiation and provides comprehensive evaluation of cardiac function and valves, however, echocardiography is not very helpful in many cases such as evaluation of extracardiac extension of mass, poor tissue characterization, and it is non diagnostic in some cases. Cross sectional imaging with cardiac computed tomography provides a three dimensional data set with excellent spatial resolution but utilizes ionizing radiation, intravenous iodinated contrast and relatively limited functional evaluation of the heart. Cardiac magnetic resonance imaging(CMR) has excellent contrast resolution that allows superior soft tissue characterization. CMR offers comprehensive evaluation of morphology, function, tissue characterization. The great benefits of CMR make CMR a highly useful tool in the assessment of cardiac masses.(Fluorine 18) fluorodeoxygluocse(FDG) positron emission tomography(PET) has become a corner stone in several oncological application such as tumor staging, restaging, treatment efficiency, FDG is a very useful imaging modality in evaluation of cardiac masses. A recent advance in the imaging technology has been the development of integrated PET-MRI system that utilizes the advantages of PET and MRI in a single examination. FDG PET-MRI provides complementary information on evaluation of cardiac masses. The purpose of this review is to provide several clinical scenarios on the incremental value of PET and MRI in the evaluation of cardiac masses. | Ahmed Fathala Mohei Abouzied Abdul-Aziz AlSugair | 2017 | World Journal of Cardiology2017，9，7： | 4 |
| 4 | In vitro and in vivo effects of ferulic acid on gastrointestinal motility:Inhibition of cisplatin-induced delay in gastric emptying in rats显示文摘AIM: To study the effects of ferulic acid on gastrointe-stinal motility both in vitro and in vivo.METHODS: Ferulic acid induced concentration-dependent stimulation of the basal tone of isolated guinea pig ileum (2-20 μmol/L) and isolated rat fundus (0.05-0.4 mmol/L). RESULTS: Ferulic acid significantly accelerated the gastrointestinal transit and gastric emptying in rats in a dose-dependent manner (50-200 mg/kg, po). Cisplatin (2.5-20 mg/kg, ip) induced a dose-dependent delay in gastric emptying in rats. Pretreatment with ferulic acid dose-dependently, significantly reversed the cisplatin-induced delay in gastric emptying. CONCLUSION: The endogenous prostaglandins (PGs) are involved in mediating the stimulant effects of ferulic acid. This effect of dietary ferulic acid may help improve other accompanying gastrointestinal symptoms such as abdominal discomfort and also may protect against emesis induced by cytotoxic drugs. | Osama A Badary Azza S Awad Mohey A Sherief Farid MA Hamada | 2006 | World Journal of Gastroenterology2006，12，33： | 2 |
| 5 | Amelioration of the physiologic and biochemical changes of acute pancreatitis using an anti TNF-α and polyclonal antibody显示文摘 | Grewal HP Mohey EDA Gaber L | 1994 | Am J Surg1994，167，： | 1 |
| 6 | Inhibition of TNF-α improves survival in an experimental model of acute panereatitis显示文摘 | Hughes CB Gaber LW Mohey el-Din AB | 1996 | Am Surg1996，62，： | 1 |
| 7 | Amelioration of the physiologic and biochemical changes of acute pancreatitis using an anti-TNF-α polyclonal antibody 显示文摘 | Grewal HP Mohey el-Din AB Gaber L | 1994 | Am J Surg1994，167，： | 1 |
| 8 | Amelioration of the physiologic and biochemical changes of acute pancreatitis using an anti-TNF-alpha polyclonal antibody显示文摘 | Grewal HP Mohey EL Din A | 1994 | Am J Surg1994，167，1： | 1 |
| 9 | Natural history of primary IgA nephropathy 显示文摘 | Berthoux FC Mohey H Afiani A | 2008 | Semin Nephrol2008，28，1： | 1 |
| 10 | Amelioration of the physiologic and biochemical changes of acute pancreatitis using an anti-TNF-α polyclonal antibody显示文摘 | Grewal HP Mohey el Din A Gaber L | 1994 | Am J Surg1994，167，1： | 1 |
| 11 | Predicting the risk for dialysis or death in IgA nephropathy显示文摘 | Berthoux F Mohey H Laurent B | 2011 | J Am Soc Nephrol2011，22，4： | 1 |
| 12 | Predicting the risk for dialysis or death in IgA nephropathy显示文摘 | Berthoux F Mohey H Laurent B | 2011 | J Am Soc Nephrol2011，22，4： | 1 |
| 13 | Significance of as sessment of serum cardiac troponin 1 and interleukin-8 in scorpionenvenomed children 显示文摘 | Meki AR Mohamed ZM Mohey El-deen HM | 2003 | Toxicon2003，41，2： | 1 |
| 14 | Induction of tumor necrosis factor in severe acute pancreatitis and its subsequent reduction after hepatic passage显示文摘 | Grewel HP Kotb M Mohey EL | 1995 | Journal of Surgery1995，115，： | 1 |
| 15 | Natural history of primary IgA nephropathy显示文摘 | Berthoux FC Mohey H Afiani A | 2008 | Semin Nephrol2008，28，1： | 1 |
| 16 | Predicting the risk for dialysis or death in IgA nephropathy显示文摘 | Berthoux F Mohey H Laurent B | 2011 | J Am Soc Nephrol2011，22，： | 1 |
| 17 | Investigation of tire contact stress distributions on pavement response显示文摘 | N Krishnamenon Mohey EI -Mously | 2002 | Journal of Transportation Engineering2002，128，2： | 1 |
| 18 | 18F-FDG Imaging:Pitfalls and Artifacts显示文摘 | Mohei M Abouzied Elpida S | 2005 | Journal of Nuclear Medicine Technology2005，33，3： | 1 |
| 19 | Predicting the risk for dialysis or death in IgA nephropathy 显示文摘 | Berthoux F Mohey H Laurent B | 2011 | J Am Soc Nephrol2011，22，4： | 1 |
| 20 | Predicting the risk fordialysis or death in IgA nephropathy显示文摘 | Berthoux F Mohey I-I Laurent B | 2011 | J Am Soc Neplarol2011，22，4： | 1 |
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