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| 1 | Analysis of Pathological data of renal biopsy at one single center in China from 1987 to 2012显示文摘 | Zhang Xueguang Liu Shuwen Tang Li Wu Jie Chen Pu Yin Zhong Li Minxia Xie Yuansheng Cai Guangyan Wei Ribao Qiu Qiang Wang Yuanda Shi Suozhu Chen Xiangmei | 2014 | Chinese Medical Journal2014，，9： | 30 |
| 2 | Shedding of TNFR1 in regenerative liver can be induced with TNF α and PMA显示文摘AIM: Liver regeneration is associated with apoptosis of hepatocytes, which is mediated via tumor necrosis factor receptor 1(TNFR1). The shedding of TNFR1 in liver regeneration and its mechanism to regulate this shedding were investigated.METHODS: The shedding of TNFR1 in liver regeneration and changes of TNF-α, PMA and plasma membrane purified from hepatocytes on this shedding process were measured with Western blot. Then, the relationship between TNFR1 shedding and apoptosis of hepatocytes induced by TNFα was studied by detecting apoptotic index.RESULTS: The shedding of TNFR1 began at 4 hours and terminated before 2 months after partial hepatectomy. In culture system, serum from rats at 36 h after partial hepatectomy could also promote this shedding process. With the stimulation of TNF α, PMA or purified plasma membrane from hepatocytes at 36 h after partial hepatectomy or from hepatocytes treated with TNF α for 2 h, membranous TNFR1 was also shed. With the stimulation of both TNF α and plasma membrane from hepatocytes affected with TNF α for 2 hor from hepatocytes at 36 h after partial hepatectomy, apoptotic index of hepatocytes decreased from 21% to 7.52 % and 8.45 %, respectively. PMA could also reduce apoptotic index to 13.67 %. This descent occurred in hepatocytes cultured in serum from rats at 36 h after partial hepatectomy too,but not in serum from rats at 2 months after partial hepatectomy and sham-operated rats.CONCLUSION: Shedding of TNFR1 may help reduce apoptosis of hepatocytes induced by TNFα. Membraneanchored metalloprotases could play a role in shedding membranous TNFR1. At the same time, PKC may take part in regulation of this shedding process. | MinXia Saho-BaiXue Cun-ShuanXu | 2002 | World Journal of Gastroenterology2002，8，6： | 10 |
| 3 | Bearing behavior and failure mechanism of squeezed branch piles显示文摘The current practice for the design of squeezed branch piles is mainly based on the calculated bearing capacity of circular piles. Insufficient considerations of the load-transfer mechanism, branch effect and failure mechanism, as well as overreliance on pile load tests, have led to conservative designs and limited application. This study performs full-scale field load tests on instrumented squeezed branch piles and shows that the shaft force curves have obvious drop steps at the branch position, indicating that the branches can effectively share the pile top load. The effects of branch position, spacing, number and diameter on the pile bearing capacity are analyzed numerically. The numerical results indicate that the squeezed branch piles have two types of failure mechanisms, i.e. individual branch failure mechanism and cylindrical failure mechanism. Further research should focus on the development of the calculation method to determine the bearing capacities of squeezed branch piles considering these two failure mechanisms. | Minxia Zhang Ping Xu Wenjie Cui Youbin Gao | 2018 | Journal of Rock Mechanics and Geotechnical Engineering2018，10，5： | 9 |
| 4 | Safety analysis of building foundations over old goaf under additional stress from building load and seismic actions显示文摘Additional displacement of the building foundations over old goaf are prone to happen under the additional loads induced by new buildings, weakening-rock mass by mining and seismic actions, which will cause serious damage to the buildings. In order to analyze the safety of the building foundations safety over the old goaf, the structure characteristics of the strata over the old goaf was investigated and the instability conditions of overhanging rocks upon old goaf were also analyzed in this paper. The results indicate that the stability of overhanging rocks is remarkably decreased by the interactions of mining fractures, earthquake force and building load, in addition, the settlement of the foundations over old goaf is increased by the instability of overhanging rocks. According to the location of a new power plant in Yima Mine and its ambient conditions, we defined the influence scope of old goaf via resistivity tomography. Based on the seismic parameters of the construction site, a numerical FLAC3 dmodel of the building foundation under the seismic actions and building load was developed. The numerical results are obtained as follows: the foundation of the main power house meets the requirement of 6°seismic fortification intensity; however, under 7° seismic fortification intensity, the maximum differential settlement of foundation between the neighboring pillars is close to the maximum allowable value, while the seismic fortification intensity reaches 8°, but the safety requirements will not be satisfied. | Xu Ping Mao Xianbiao Zhang Minxia Zhou Yuejin Yu Bangyong | 2014 | International Journal of Mining Science and Technology2014，24，5： | 5 |
| 5 | Chiral cyanide-bridged 1D Fe~Ⅲ-Mn~Ⅲ heterobimetallic chains: Synthesis, structures and magnetic properties显示文摘Two couples of enantiomerically pure chiral cyano-bridged heterobimetallic one-dimensional (1D) chain complexes: [Mn((R,R)-Salphen)Fe(Tp)(CN)3]n (1) and [Mn((S,S)-Salphen)Te(Tp)(CN)3]n (2) (Salphen = N,N'-1,2-diphenylethylenebis (salicylideneiminato) dianion, Tp = tris(pyrazolyl) hydroborate), [Mn((R,R)-Salphen)Fe(Tp*)(CN)3·2H2O]n (3) and [Mn((S,S)-Salphen)Fe(Tp*)(CN)3·2H2O]n (4) (Tp* = hydridotris (3,5-dimethylpyrazol-1-yl) borate), have been successfully synthesized by the reactions of MnIII schiff-base complexes with the tricyanometalate building block, [(LTp)Fe(CN)3]- (LTp = Tp or Tp*). All complexes are made up of neutral cyano-bridged zigzag double chains with (-Fe-C≡N-Mn-N≡C-)n as the repeating unit. Circular dichroism (CD) spectra confirm the enantiomeric nature of the optically active complexes. Magnetic studies demonstrate that ferromagnetic interactions are operative in these complexes. The ferromagnetic couplings become weak in the chains with the bending of the Mn-N≡C angles. | YAO MinXia ZHENG Qi GAO Feng LI YiZhi ZUO JingLin | 2012 | Science China Chemistry2012，55，6： | 4 |
| 6 | Sialic acid-engineered mesoporous polydopamine nanoparticles loaded with SPIO and Fe3+as a novel theranostic agent for T1/T2 dual-mode MRI-guided combined chemo-photothermal treatment of hepatic cancer显示文摘diagnostic and therapeutic capability are highly needed for the treatment of hepatic cancer.Herein,we aimed to develop a novel mesoporous polydopamine(MPDA)-based theranostic agent for T1/T2 dual magnetic resonance imaging(MRI)-guided cancer chemo-photothermal therapy.Superparamagnetic iron oxide(SPIO)-loaded MPDA NPs(MPDA@SPIO)was firstly prepared,followed by modifying with a targeted molecule of sialic acid(SA)and chelating with Fe^(3+)(SA-MPDA@SPIO/Fe^(3+) NPs).After that,doxorubicin(DOX)-loaded SA-MPDA@SPIO/Fe^(3+) NPs(SA-MPDA@SPIO/DOX/Fe^(3+))was prepared for tumor theranostics.The prepared SAPEG-MPDA@SPIO/Fe^(3+) NPs were water-dispersible and biocompatible as evidenced by MTT assay.In vitro photothermal and relaxivity property suggested that the novel theranostic agent possessed excellent photothermal conversion capability and photostability,with relaxivity of being r1=4.29 mM��1s��1 and r2=105.53 mM��1s��1,respectively.SAPEG-MPDA@SPIO/Fe^(3+) NPs could effectively encapsulate the DOX,showing dual pH-and thermal-triggered drug release behavior.In vitro and in vivo studies revealed that SA-MPDA@SPIO/DOX/Fe^(3+) NPs could effectively target to the hepatic tumor tissue,which was possibly due to the specific interaction between SA and the overexpressed E-selectin.This behavior also endowed SA-MPDA@SPIO/DOX/Fe^(3+)NPs with a more precise T1-T2 dual mode contrast imaging effect than the one without SA modification.In addition,SAPEG-MPDA@SPIO/DOX/Fe^(3+) NPs displayed a superior therapeutic effect,which was due to its active targeting ability and combined effects of chemotherapy and photothermal therapy.These results demonstrated that SAPEG-MPDA@SPIO/DOX/Fe^(3+) NPs is an effective targeted nanoplatform for tumor theranostics,having potential value in the effective treatment of hepatic cancer. | Gaofeng Shu Minjiang Chen Jingjing Song Xiaoling Xu Chenying Lu Yuyin Du Min Xu Zhongwei Zhao Minxia Zhu Kai Fan Xiaoxi Fan Shiji Fang Bufu Tang Yiyang Dai Yongzhong Du Jiansong Ji | 2021 | Bioactive Materials2021，6，5： | 4 |
| 7 | Leakage research on supercritical carbon dioxide fluid in rolling piston expander显示文摘The leakage research on supercritical carbon dioxide fluid in rolling piston expander was investigated experimentally.Using expander instead of throttle valve is an important way to improve the efficiency of carbon dioxide refrigeration system.However,the supercritical fluid leakage in expander is serious and is the main factor affecting the expander's efficiency.This paper presented and compared four classic leakage models.The analysis indicated that laminar leakage model is suitable in leakage simulation of expander.A leakage test system,including the leakage test part which has two types of leakage specimens with different gaps ranging from 5 to 15 m,was established.The experimental results indicated that lubricant film played an important role.When the leakage clearance of cylindrical specimen was 5 m,the mass flow rate of leakage was about 0.88 g s-1.The data was 3.638 g s-1 with leakage clearance being 10 m and 7.11g s-1 with leakage clearance being 15 m.A modified leakage model was developed,whose average deviation was within 10% compared with the experimental data.At last,this paper simulated the leakage in rolling piston expander presented by Tian et al.(2010).The leakage between rolling piston and cylinder was the most serious part with the value up to 0.04 kg s-1. | TIAN Hua MA YiTai LI MinXia LIU ShengChun WANG KaiYang | 2012 | Science China(Technological Sciences)2012，55，6： | 3 |
| 8 | Research on spatiotemporal change of ecological capacity and driving forces in the LRGR显示文摘纵的范围峡区域(LRGR ) 是为在中国的生物多样性保护的一个关键区域。另外它为富有的资源,复杂环境和脆弱的生态系统是著名的。在 LRGR,在生态的安全级别和生态的能力有大差别。人的骚乱和生态系统变化是重要的。分析生态的能力的空间与时间的变化具有重要性让管理实现生态的管理。作为一个盒子在 LRGR 核心区域拿县,在 GIS 的帮助下,我们使用了生态的脚印方法在二 scalesthe 学习生态的能力的空间与时间的变化城市的更大的规模和县的更小的规模。然后,我们讨论了由主要部件分析(PCA ) 影响了生态的能力的开车因素。结果证明生态的脚印,生态的能力和生态的安全级别在 LRGR 从县清楚地变化了到县。地区性的生态的能力从北方逐年减少了,南方到 LRGR 的中间。根据驱动力的分析,人均的生态的能力与人口, GDP,和另外的开车因素有否定关联。在这些因素之中,社会经济和人口在生态的能力上有很重要的影响。并且驾驶因素的空间变化决定了生态的能力的空间与时间的变化。 | WEN MinXia LIU ShiLiang CUI BaoShan | 2007 | Chinese Science Bulletin2007，52，A02： | 3 |
| 9 | Novel soybean peptide iglycin ameliorates insulin resistance of high-fat diet fed C57BL/6J mice and differentiated 3T3L1 adipocytes with improvement of insulin signaling and mitochondrial function显示文摘Soy consumption has been associated with potential health benefits in reducing chronic diseases.These physiological functions have been attributed to soy proteins or more commonly to bioactive peptides.Thus,more studies are required to identify these bioactive peptides,and elucidate their biological mechanisms of action.In the present study,a novel peptide iglycin was purifi ed from soybean seeds with a molecular mass of 3.88 k Da.Thereafter,iglycin reduced fasting blood glucose and restored insulin sensitivity of C57 BL/6 J mice on a high-fat diet with increased phosphorylation of insulin receptor substrate 1(IRS1)and AKT in adipose tissue.Furthermore,it improved glucose uptake,induced translocation of intracellular GLUT4 to plasma membrane and activation of insulin signaling in adipocytes under insulin-resistant condition.In addition,it decreased reactive oxygen species production,lipid peroxidation and inhibited adipocyte apoptosis with improved mitochondrial function as evidenced by up-regulation of succinate dehydrogenase activity,mitochondrial membrane potential and intracellular ATP store.These data suggested that iglycin ameliorated insulin resistance via activation of insulin signaling,which was associated with inhibition of oxidative stress,adipocyte apoptosis,and improvement of mitochondrial function. | Yinghuan Wu Ran Zhao Minxia Li Huiyun Li Zhengwang Chen Yanying Zhao | 2022 | Food Science and Human Wellness2022，11，6： | 3 |
| 10 | Research and application of CO_2 refrigeration and heat pump cycle显示文摘The environmental problem caused by refrigerant has become the focus all over the world.As the most typical natural refrigerant,CO2,of course,becomes the research focus.This paper introduces the development and application status of CO2 refrigeration and heat pump technology.The researches on CO2 refrigeration and heat pump,carried out by Thermal Energy Research Institute,Tianjin University,also are presented in this paper. | TIAN Hua,YANG Zhao,LI MinXia & MA YiTai Thermal Energy Research Institute,Tianjin University,Tianjin 300072,China | 2009 | Science China(Technological Sciences)2009，52，6： | 3 |
| 11 | Spray-drying assisted layer-structured H_(2)TiO_(3) ion sieve synthesis and lithium adsorption performance显示文摘A spray-drying assisted solid-state method to prepare spherical layer-structured H_(2)TiO_(3) ion sieve(LSTIS)particles is reported herein.The effects of synthesis parameters(calcination temperature,calcination time,and the lithium-titanium molar ratio)on adsorption-desorption performance(the delithiation ratio,titanium dissolution loss,and the adsorption capacity)were investigated.The as-prepared LSTIS exhibited an equilibrium adsorption capacity of 30.08 mg·g^(-1)(average of 25.85 mg·g^(-1) over 5 cycles)and ultra-low titanium dissolution loss of less than 0.12%(average of 0.086%over 5 cycles).The LSTIS showed excellent selectivity toward Li^(+) in Na^(+),K^(+),Mg^(2+),and Ca^(2+) coexisting saline solutions where its adsorption capacity reached 27.45 mg·g^(-1) and the separation factors of Li^(+) over the coexisting cations exceeded 100.The data suggests that the LSTIS is promising to competitively enrich Li^(+) from saline solutions. | Minxia Liu Dang Wu Dongling Qin Gang Yang | 2022 | Chinese Journal of Chemical Engineering2022，35，5： | 3 |
| 12 | Effect of disconnector and high-voltage conductor on propagation characteristics of PD-induced UHF signals显示文摘UHF(ultra high frequency)method has been widely used in PD(partial discharge)detection for its high sensitivity.The resonance,distortion,and attenuation appearing in the propagation process of UHF signals in GIS(gas insulated switchgear)will influence the real situation of PD detection.Therefore,it is necessary to investigate the effect of GIS components such as disconnectors or high voltage conductors on the propagation characteristics of PD-induced UHF signals in various voltage classes GIS.The factors of PD signals propagation characteristics in axial and radial directions are both analysed to avoid the effect caused by placement of sensor in this paper.First,the simulation models of GIS are built based on FDTD(finite difference time domain)method.Then the propagation characteristics of PD-induced UHF signals are studied in the GIS with different disconnector gap lengths and different high voltage conductor radii.Finally,the reliability of the simulation results is verified by compared with laboratory tests.The disconnector gap and the change of conductor radii can both result in the signals attenuation which rises highest in the direction of 180°.The lower the GIS class voltage is,the larger the attenuation of signals after passing through disconnector gap is. | Minxia Shi Xutao Han Xuanrui Zhang Zheming Zhang Junhao Li | 2018 | High Voltage2018，3，3： | 2 |
| 13 | Joint Bearing Mechanism of Coal Pillar and Backfilling Body in Roadway Backfilling Mining Technology显示文摘In the traditional mining technology,the coal resources trapped beneath surface buildings,railways,and water bodies cannot be mined massively,thereby causing the lower coal recovery and dynamic disasters.In order to solve the aforementioned problems,the roadway backfilling mining technology is developed and the joint bearing mechanism of coal pillar and backfilling body is presented in this paper.The mechanical model of bearing system of coal pillar and backfilling body is established,by analyzing the basic characteristics of overlying strata deformation in roadway backfilling mining technology.According to the Ritz method in energy variation principle,the elastic solution expression of coal pillar deformation is deduced in roadway backfilling mining technology.Based on elastic-viscoelastic correspondence principle,combining with the burgers rheological constitutive model and Laplace transform theory,the viscoelastic solution expression of coal pillar deformation is obtained in roadway backfilling mining technology.By analyzing the compressive mechanical property of backfilling body,the time formula required for coal pillar and backfilling body to play the joint bearing function in roadway backfilling mining technology is obtained.The example analysis indicates that the time is 140 days.The results can be treated as an important basis for theoretical research and process design in roadway backfilling mining technology. | Zhengzheng Cao Ping Xu Zhenhua Li Minxia Zhang Yu Zhao Wenlong Shen | 2018 | Computers, Materials & Continua2018，，2： | 2 |
| 14 | Exergy analysis of transcrit- ical carbon dioxide refrigeration cycle with an expander 显示文摘 | Yang Junlan Ma Yitai Li Minxia | 2005 | Energy2005，30，： | 1 |
| 15 | The status and future of energy efficiency standard of water chillers in China显示文摘 | Tian Hua Ma Yitai Li Minxia | 2010 | Energy Police2010，38，11： | 1 |
| 16 | Exergy analysis of transcritical carbon dioxide refrigeration cycle with an expander显示文摘 | Yang Junlan Ma Yitai Li Minxia | 2005 | Energy2005，，30： | 1 |
| 17 | Some design features of CO2 swing piston expander 显示文摘 | Guan Haiqing Ma Yitai Li Minxia | 2006 | Applied Thermal Engineering2006，26，2： | 1 |
| 18 | Some design features of CO2 swing piston expander 显示文摘 | Guan Haiqing Ma Yitai Li Minxia | 2006 | Applied Thermal Engineering2006，26，23： | 1 |
| 19 | Heart valve replacement perioperative health education and guidance显示文摘 | Zhao Minxia | 2011 | Well xingshugang mountain med- ical college journal2011，9，4： | 1 |
| 20 | Theoretical analysis and experimental research on tianscritical C02two stage compression cycle withtwo gas coolers (TSCC +TG) and the cycle with intercooler (TSCC +IC) 显示文摘 | Hongli Wang Yitai Ma’Jingmi Tian Minxia Li | 2011 | Energy Conversion and Management2011，52，89： | 1 |
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