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110篇 您的检索式:作者名="Mingqi"
    题名 作者 年代 出处 被引量
1Impact of social isolation and resident intruder stress on aggressive behavior in the male rat显示文摘Stress studies frequently utilize physical stressors to establish animal models of stress.In the majority of cases,these models are not consistent with human circumstances.The present study simulated a social isolation plus resident intruder stress model in the rat.The rats were subjected to daily social isolation and resident intruder stress for 2 weeks.Behaviors were then tested.Rats subjected to social stress exhibited different aggressive behavior styles;some rats had greater scores on composite aggression behaviors,as well as locomotor and exploratory activity,but lower scores on latency than others.The high-aggressive group exhibited predominantly anger-out,while the low-aggressive group exhibited anger-in.Results suggest that social isolation plus resident intruder may serve as an appropriate model for anger-in and anger-out emotion modeling in the rat.Sheng Wei Huiyun Zhang Jie Gao Ling Xue Peng Sun Yubin Chao Gang Xue Mingqi Qiao 2010Neural Regeneration Research2010,5,15:23
2Material transportation and fluid-melt activity in the subduction channel: Numerical modeling显示文摘The subduction channel is defined as a planar to wedge-like area of variable size,internal structure and composition,which forms between the upper and lower plates during slab subduction into the mantle.The materials in the channel may experience complex pressure,temperature,stress and strain evolution,as well as strong fluid and melt activity.A certain amount of these materials may subduct to and later exhume from>100 km depth,forming high to ultra-high pressure rocks on the surface as widely discovered in nature.Rock deformation in the channel is strongly assisted by metamorphic fluids activities,which change composition and mechanical properties of rocks and thus affect their subduction and exhumation histories.In this study,we investigate the detailed structure and dynamics of both oceanic and continental subduction channels,by conducting highresolution petrological-thermomechanical numerical simulations taking into account fluid and melt activities.The numerical results demonstrate that subduction channels are composed of a tectonic rock melange formed by crustal rocks detached from the subducting slab and the hydrated mantle rocks scratched from the overriding plate.These rocks may either extrude sub-vertically upward through the mantle wedge to the crust of the upper plate,or exhume along the subduction channel to the surface near the suture zone.Based on our numerical results,we first analyze similarities and differences between oceanic and continental subduction channels.We further compare numerical models with and without fluid and melt activity and demonstrate that this activity results in strong weakening and deformation of overriding lithosphere.Finally,we show that fast convergence of orogens subjected to fluid and melt activity leads to strong deformation of the overriding lithosphere and the topography builds up mainly on the overriding plate.In contrast,slow convergence of such orogens leads to very limited deformation of the overriding lithosphere and the mountain building mainly occurs on the subducting plate.LI ZhongHai LIU MingQi Taras GERYA 2015Science China Earth Sciences2015,58,8:18
3Starch grains from dental calculus reveal ancient plant foodstuffs at Chenqimogou site, Gansu Province显示文摘Chenqimogou site, located at the south bank of Tao River, is comprised of a large group of graves dated to ~4000 a BP. For its large scale, unique mortuary system, and abundant of typical artifacts, the site was named one of 'Top Ten Archaeological Discoveries of 2008 in China'. Many intact human skeletons have been excavated from the graves. Three teeth from two adult skeletons excavated from graves M187 and M194 were examined. Forty-eight starch grains were retrieved from dental calculus of three teeth. Six of those starch grains could not be identified because of damage. The others were classified into seven groups. Most of them were from wheat (Triticum aestivum) and/or barley (Hordeum vulgare). Remains possibly from foxtail millet (Setaria italica), buckwheat (Fagopyrum esculentum), gingkgo (Ginkgo biloba), acorn (Quercus spp.), bean, roots or tubers were identified. Ancient starch grains from dental calculus indicate that human foodstuffs primarily sourced from wheat, buckwheat, and foxtail millet. Acorn, beans, tubers or roots were supplements. A variety of starch grains retrieved from dental calculus revealed that diverse crops were cultivated in the Chenqimogou site 4000 years ago, and both dry-land farming and gathering were engaged.LI MingQi YANG XiaoYan WANG Hui WANG Qiang JIA Xin GE QuanSheng 2010Science China Earth Sciences2010,53,5:11
4Isolation of marine benzo[a]pyrene-degrading Ochrobactrum sp. BAP5 and proteins characterization显示文摘A bacterial strain BAP5 with a relatively high degradation ability of benzo[a]pyrene (BaP) was isolated from marine sediments of Xiamen Western Sea, China and identified as Ochrobactrum sp. according to 16S rRNA gene sequence as well as Biolog microbial identification system. Strain BAP5 could grow in mineral salt medium with 50 mg/L of BaP and degrade about 20% BaP after 30 d of incubation. Ochrobactrum sp. BAP5 was able to utilize other polycyclic aromatic hydrocarbons (PAHs) (such as phenanthrene, pyrene and fluoranthene) as the sole carbon source and energy source, suggesting its potential application in PAHs bioremediation. The profile of total soluble protein from Ochrobactrum sp. BAP5 was also investigated. Some over- and special-expressed proteins of strain BAP5 when incubated with the presence of BaP were detected by two-dimensional polyacrylamide gel electrophoresis, and found to be related with PAHs metabolism, DNA translation, and energy production based on peptide fingerprint analysis through matrix-assisted laser desorption/ionization-time of flight mass spectrometry.WU Yirui HE Tengteng ZHONG Mingqi ZHANG Yueling LI Enmin HUANG Tongwang HU Zhong 2009Journal of Environmental Sciences2009,21,10:10
5Existence of solutions for a critical fractional Kirchhoff type problem in(49)R^N显示文摘This paper concerns with the existence of solutions for the following fractional Kirchhoff problem with critical nonlinearity:(∫∫_(R^(2N)(|u(x)-u(y)|~2)/(|x-y|^(N+2s)dxdy)^(θ-1)(-?)~su = λh(x)u^(p-1)+u^(2_s*-1) in R^N,where(-?)~s is the fractional Laplacian operator with 0 < s < 1, 2_s~*= 2N/(N-2s), N > 2s, p ∈(1, 2_s~*),θ∈ [1, 2_s~*/2), h is a nonnegative function and λ is a real positive parameter. Using the Ekeland variational principle and the mountain pass theorem, we obtain the existence and multiplicity of solutions for the above problem for suitable parameter λ > 0. Furthermore, under some appropriate assumptions, our result can be extended to the setting of a class of nonlocal integro-differential equations. The remarkable feature of this paper is the fact that the coefficient of fractional Laplace operator could be zero at zero, which implies that the above Kirchhoff problem is degenerate. Hence our results are new even in the Laplacian case.XIANG MingQi ZHANG BinLin QIU Hong 2017Science China Mathematics2017,60,9:9
6Pt/Y2O3:Eu3+ composite nanotubes: Enhanced photoluminescence and application in dye-sensitized solar cells显示文摘Y (哦)3:Eu3+ nanotubes 用一个灵巧的热水的方法被综合,然后,磅粒子在使用真空抽取的联合并且退火的 nanotubes 的表面上被种。产生 Pt/Y 2 O 3:Eu3+合成 nanotubes 不仅在 255-nm 或 468-nm 刺激下面展出了提高的红光而且能也被用来改进敏化染料的太阳能电池的效率,导致8.33%的效率,没有合成 nanotubes ,它与一节太阳能电池相比代表11.96%的重要改进。电气化学的阻抗光谱学结果显示 TiO 2-dye|I 3-/I - 电解质的界面的抵抗 TiO 2-Pt/Y2 合成房间多是的 O 3:Eu3+ 比一个纯 TiO 2 房间的小。另外, TiO 2-Pt/Y2 O 3:Eu3+ 合成房间比纯 TiO 2 房间展出了一更短的电子运输时间和更长的电子再结合时间。Mingqi Yu Jiamin Su Guofeng Wang Yadong Li 2016Nano Research2016,9,8:6
7Multilayer black phosphorus as saturable absorber for an Er:Lu_(2)O_(3) laser at~3 μm显示文摘Multilayer black phosphorus(BP) nanoplatelets of different thicknesses were prepared by the liquid phase exfoliation method and deposited onto yttrium aluminum garnet substrates to form saturable absorbers(SAs). These were characterized with respect to their thickness-dependent saturable absorption properties at 3 μm. The BP-SAs were employed in a passively Q-switched Er:Lu_2O_3 laser at 2.84 μm. By using BP exfoliated in different solvents,stable pulses as short as 359 ns were generated at an average output power of up to 755 m W. The repetition rate in the experiment was 107 k Hz, corresponding to a pulse energy of 7.1 μJ. These results prove that BP-SAs have a great potential for optical modulation in the mid-infrared range.Mingqi Fan Tao Li Shengzhi Zhao Guiqiu Li Xiaochun Gao Kejian Yang Dechun Li Christian Krankel 2016Photonics Research2016,4,5:5
8Dynamics of thinning and destruction of the continental cratonic lithosphere: Numerical modeling显示文摘Thinning of the cratonic lithosphere is common in nature, but its destruction is not. In either case, the mechanisms for both thinning and destruction are still widely under debate. In this study, we have made a review on the processes and mechanisms of thinning and destruction of cratonic lithosphere according to previous studies of geological/geophysical observations and numerical simulations, with specific application to the North China Craton(NCC). Two main models are suggested for the thinning and destruction of the NCC, both of which are related to subduction of the oceanic lithosphere. One is the 'bottom-up' model, in which the deeply subducting slab perturbs and induces upwelling from the hydrous mantle transition zone(MTZ). The upwelling produces mantle convection and erodes the bottom of the overriding lithosphere by the fluid-meltperidotite reaction. Mineral compositions and rheological properties of the overriding lithospheric mantle are changed, allowing downward dripping of lithospheric components into the asthenosphere. Consequently, lithospheric thinning or even destruction occurs. The other is the 'top-down' model, characterized by the flat subduction of oceanic slab beneath the overriding cratonic lithosphere. Dehydration reactions from the subducting slab would significantly hydrate the lithospheric mantle and decrease its rheological strength. Then the subduction angle may be changed from shallow to steep, inducing lateral upwelling of the asthenosphere. This upwelling would heat and weaken the overriding lithospheric mantle, which led to the weakened lithospheric mantle dripping into the asthenosphere. These two models have some similarities, in that both take the subducting oceanic slab and relevant fluid migration as the major driving mechanism for thinning or destruction of the overriding cratonic lithosphere. The key difference between the two models is the effective depth of the subducting oceanic slab. One is stagnation and flattening in the MTZ, whereas the other is flat subduction at the bottom of the cratonic lithosphere. In the NCC, the eastern lithosphere was likely affected by subduction of the Izanagi slab during the Mesozoic, which would have perturbed the asthenosphere and the MTZ, and induced fluid migration beneath the NCC lithosphere. The upwelling fluid may largely have controlled the reworking of the NCC lithosphere. In order to discuss and analyze these two models further, it is crucial to understand the role of fluids in the subduction zone and the MTZ. Here, we systematically discuss phase transformations of hydrous minerals and the transport processes of water in the subduction system. Furthermore, we analyze possible modes of fluid activity and the problems to explore the applied feasibility of each model. In order to achieve a comprehensive understanding of the mechanisms for thinning and destruction of cratonic lithosphere, we also consider four additional possible dynamic models: extension-induced lithospheric thinning, compression-induced lithospheric thickening and delamination, large-scale mantle convection and thermal erosion, and mantle plume erosion. Compared to the subduction-related models presented here, these four models are primarily controlled by the relatively simple and single process and mechanism(extension, compression, convection, and mantle plume, respectively), which could be the secondary driving mechanisms for the thinning and destruction of lithosphere.Mingqi LIU Zhonghai LI 2018Science China Earth Sciences2018,61,7:5
9Review of Soft Linear Actuator and the Design of a Dielectric Elastomer Linear Actuator显示文摘Natural muscle provides excellent motilities for animals.As the basic unit of the muscle system,the skeletal muscle fibers function as a soft linear actuator.Inspired by the muscle fibers,researchers have developed various soft active devices with linear actuation.This paper reviews several soft linear actu ators,such as the dielec trie elastomer,t hermal responsive hydrogels,pneumatic artificial muscle,and conducting polymers.The actuation mechanisms and performances of these soft linear actuators are summarized.Based on the dielectric elastomer,we propose a design of a hybrid system with linear actuation,driven by both the electric motor and dielectric elasto mer cone.The elec tromechanical behaviors of the dielec trie elastomer cone have been investigated in both experiment and finite element analysis.This work may guide the further design of soft actuators and robots.Xunuo Cao Mingqi Zhang Zhen Zhang Yi Xu Youhua Xiao Tiefeng Li 2019Acta Mechanica Solida Sinica2019,32,5:4
10Effectiveness and safety of Suhuang Zhike capsule(苏黄止咳胶囊)as adjuvant treatment for acute exacerbation of chronic obstructive pulmonary disease:a systematic review and Meta-analysis显示文摘OBJECTIVE:To evaluate the efficacy and safety of Suhuang Zhike capsule(苏黄止咳胶囊) in the adjuvant treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD).METHODS:The database including PubMed,Embase,Cochrane Library,China National Knowledge Infrastructure Database,China Science and Technology Journal Database,Chinese Biomedical Literature Database and Wanfang Data was searched.The retrieval time was from database establishment to May 2021.Randomized controlled trial(RCT) of Suhuang zhike capsule adjuvant treatment for AECOPD was included.The quality of the studies was independently evaluated and cross-checked by two reviewers,and Meta-analysis was performed by using RevMan5.3 software.RESULTS:Thirteen RCT results were included with a total sample number of 1195 cases,including 597 in the experimental group and 598 in the control group.The results showed that Suhuang zhike capsule adjuvant treatment of AECOPD could improve the total clinical effect rate compared with conventional treatment.Suhuang zhike capsule adjuvant treatment could improve forced vital capacity(FVC),forced expiratory volume in one second(FEV1),FEV1/FVC,peak expiratory flow(PEF) and other pulmonary function indexes;decrease Creactive protein(CRP),white blood cells,neutrophils and other infectious indicators;besides,the 1-year recurrence rate of the disease was decreased(all P < 0.05).CONCLUSIONS:Suhuang Zhike capsule can improve the lung function and clinical efficacy of AECOPD,thus increasing the exercise endurance,and reducing the infection and recurrence rate in AECOPD patients.DAI Linfeng ZHUANG Yan LüHai CHEN Mingqi WANG Xing 2023Journal of Traditional Chinese Medicine2023,43,2:3
11Mechanisms of extracellular signal-regulated kinase/cAMP response element-binding protein/brain-derived neurotrophic factor signal transduction pathway in depressive disorder显示文摘The extracellular signal-regulated kinase/cAMP response element-binding protein/brain-derived neurotrophic factor signal transduction pathway plays an important role in the mechanism of action of antidepressant drugs and has dominated recent studies on the pathogenesis of depression. In the present review we summarize the known roles of extracellular signal-regulated kinase, cAMP response element-binding protein and brain-derived neurotrophic factor in the pathogenesis of depression and in the mechanism of action of antidepressant medicines. The extracellular signal-regulated kinase/cAMP response element-binding protein/brain-derived neurotrophic factor pathway has potential to be used as a biological index to help diagnose depression, and as such it is considered as an important new target in the treatment of depression.Hongyan Wang Yingquan Zhang Mingqi Qiao 2013Neural Regeneration Research2013,8,9:3
12Systematic study on the mechanical and electric behaviors of the nonbuckling interconnect design of stretchable electronics显示文摘Recently, we developed a nonbuckling interconnect design that provides an effective approach to simultaneously achieving high elastic stretchability, easiness for encapsulation, and high electric performance for stretchable electronics. This paper aims to systematically study its mechanical and electric behaviors, including comparisons of the nonbuckling and buckling interconnect designs on stretchability, effects of the thickness on electric performance, and modeling and experimental investigations on the finite deformation mechanics. It is found that the results on stretchability depend on the layouts. Long straight segments and small arc radii for nonbuckling interconnects yield an enhancement of stretchability, which is much better than that of buckling designs. On the other hand, shorter straight segments or thicker interconnects are better to lower the resistances of interconnects.Therefore, optimization of the designs needs to balance the requirements of both the mechanical and electric performances. The finite deformation of interconnects during stretching is analyzed. The established analytic model is well validated by both the finite element modeling and experimental investigations. This work is key for providing the design guidelines for nonbucklingbased stretchable electronics.Hao Liu RiYe Xue JianQiao Hu XueCheng Ping HuaPing Wu MingQi Huang Han Zhang Xu Guo Rui Li YuLi Chen YeWang Su 2018Science China(Physics,Mechanics & Astronomy)2018,61,11:3
13Event-Driven Top-k Queries in Sensor Networks with Multi Microenvironments显示文摘In the emerging area of sensor-based systems, a significant challenge is to develop reliable, energy efficient methods to extract useful information from the distributed sensory data. Existing top-k query algorithms of sensor networks are only applicable to the sensor networks with single Microenvironment(ME). Besides, these approaches rely on using raw sensor readings, which handling these raw sensory data requires large amount of data transmission and is memory-consuming. In this paper we highlight the multiple MEs in sensor networks and propose a novel event-driven approximate top-k query framework based on fuzzy method. Firstly, membership function of fuzzy method is introduced to describe the global potential event confidence. Subsequently, non-uniform membership degree subranges based linguistic variables instead of numeric sensor readings are used for in-network top-k event fusion. Also two distributed event-driven approximate top-k query algorithms are devised. Theoretical analysis as well as extensive simulations based on synthetic and real data sets show that our framework reduces the data transmission significantly and the query results are more interpretable with quality guarantees.LI Yinglong LV Mingqi YANG Lianghuai 2015Chinese Journal of Electronics2015,24,2:2
14Tumor-targeted delivery of siRNA to silence Sox2 gene expression enhances therapeutic response in hepatocellular carcinoma显示文摘RNA interference(RNAi)is one of the most promising methods for the treatment of malignant tumors.However,developing an efficient biocompatible delivery vector for small interfering RNA(siRNA)remains a challenging issue.This study aimed to prepare a non-viral tumor-targeted carrier,named RGDfC-modified functionalized selenium nanoparticles(RGDfC-SeNPs).RGDfC-SeNPs were used to selectively deliver siSox2 to HepG2 liver cancer cells and tissues for the treatment of hepatocellular carcinoma(HCC).In the current study,RGDfC-SeNPs were successfully synthesized and characterized.It was shown that RGDfC-SeNPs could effectively load siSox2 to prepare an antitumor prodrug RGDfC-Se@siSox2.RGDfC-Se@siSox2 exhibited selective uptake in HepG2 liver cancer cells and LO2 normal liver cells,indicating RGDfC-SeNPs could effectively deliver siSox2 to HepG2 liver cancer cells.RGDfC-Se@siSox2 entered HepG2 cells via clathrin-mediated endocytosis by firstly encircling the cytoplasm and then releasing siSox2 in the lysosomes.RGDfC-Se@siSox2 could effectively silence Sox2 and inhibit the proliferation,migration and invasion of HepG2 cells.RGDfC-Se@siSox2 induced HepG2 cells apoptosis most likely via overproduction of reactive oxygen species and disruption of the mitochondrial membrane potentials.Most importantly,RGDfC-Se@siSox2 significantly inhibited the tumor growth in HepG2 tumor-bearing mice without obvious toxic side effects.These studies indicated that RGDfC-SeNPs may be an ideal gene carrier for delivering siSox2 to HepG2 cells and that RGDfC-Se@siSox2 may be a novel and highly specific gene-targeted prodrug therapy for HCC.Yu Xia Guoyi Tang Yi Chen Changbing Wang Min Guo Tiantian Xu Mingqi Zhao Yongjian Zhou 2021Bioactive Materials2021,6,5:2
15Performance analysis of DFT spread generalized multi-carrier systems显示文摘Discrete Fourier transform-spread generalized multi-carrier (DFT-S-GMC) based single carrier-frequency division multiple access (SC-FDMA) scheme is a promising solution for uplink transmission of broadband wireless communication. In this paper, the impact of non-perfect orthogonal prototype filter to the performance of the DFT-S-GMC system is discussed. Single sub-band frequency-domain equalization (FDE) method is presented and the performance loss caused by FDE-tone discarding is analyzed. Moreover, the post-processing signal to interference plus noise ratio (SINR) of DFT-S-GMC receiver over multi-path channel is addressed. The theoretical analysis illustrates that the non-perfect orthogonal prototype filter results in inter-symbol interference (ISI) and inter-sub-band interference (IBI), and the variance of the ISI is still less than 1e-4 and much larger than that of IBI. By designing proper system parameters, the reconstruction error due to FDE-tones discarding can be controlled under -40 dB; the post-processing SINR of the DFT-S-GMC receiver with minimum mean square error (MMSE) equalization is higher than that with zero forcing (ZF) equalization. The theoretical performances are verified by extensive simulation results.LI MingQi ZHANG XiaoDong 2009Science in China(Series F)2009,52,12:2
16Photocrosslinking silver nanoparticles–aloe vera–silk fibroin composite hydrogel for treatment of full-thickness cutaneous wounds显示文摘Damage to the skin causes physiological and functional issues.The most effective treatment approach is the use of wound dressings.Silk fibroin(SF)is a promising candidate biomaterial for regulating wound healing;however,its antibacterial properties and biological activity must be further improved.In this study,a photocrosslinking hydrogel was developed to treat full-thickness cutaneous wounds.The composite hydrogel(Ag-AV-SF hydrogel)was prepared by introducing the silver nanoparticles(AgNPs)and aloe vera(AV)as the modifiers.In vitro study exhibited great antibacterial ability,biocompatibility and cell-proliferation and-migration-promoting capacities.It also showed the pH-response releasing properties which release more AgNPs in a simulated chronic infection environment.The healing effect evaluation in vivo showed the healing-promoting ability of the Ag-AV-SF hydrogel was stronger than the single-modifiers groups,and the healing rate of it reached 97.02%on Day 21,higher than the commercial wound dressing,silver sulfadiazine(SS)cream on sale.Additionally,the histological and protein expression results showed that the Ag-AV-SF hydrogel has a greater effect on the pro-healing regenerative phenotype with M2 macrophages at the early stage,reconstructing the blood vessels networks and inhibiting the formation of scars.In summary,the Ag-AV-SF hydrogel developed in this study had good physical properties,overwhelming antibacterial properties,satisfactory biocompatibility and significantly promoting effect on cell proliferation,migration and wound healing.Overall,our results suggest that the Ag-AV-SF hydrogel we developed has great potential for improving the wound healing in clinical treatment.Yangkun Liu JinChuan Fan MingQi Lv Kepeng She Jiale Sun Qingqing Lu Changhao Han SongTao Ding Shuang Zhao GuiXue Wang YuChan Zhang GuangChao Zang 2021Regenerative Biomaterials2021,8,6:2
17Tribological properties of surface modified nano-alumina/epoxy composites 显示文摘Ji Qinli Zhang Mingqi Rong Minzou 2004J Mater Sci2004,39,21:1
18Sliding wear behavior of epoxy containing nano-Al203 particles with differ- ent pretreatments显示文摘Shi Gong Zhang Mingqi Rong Minzou 2004Wear2004,256,1112:1
19Analysis of CFO effects on and phase compensation method for SC-FDMA systems显示文摘Discrete Fourier transform spread orthogonal frequency division multiplexing (DFT-S-OFDM) based single carrier-frequency division multiple access (SC-FDMA) is accepted as the uplink transmission scheme by the 3GPP-long term evolution standardization organization. In this paper, the effects of carrier frequency offset (CFO) on DFT-S-OFDM system are analyzed for both single user and multiple user accessing scenarios. According to the analysis, the CFO results in the attenuation, linear phase rotation, inter-symbol interference (ISI) and inter-sub-carrier interference (ICI) on the demodulated symbols of each desired user, and the multi-user interference (MUI) among uplink users. The theoretical values of ISI, ICI, and signal to interference ratio (SIR) are presented for the DFT-S-OFDM system with full and partial bandwidth detection respectively. A phase compensation method is proposed to reduce the effect of linear phase rotation on the demodulated symbols. Finally, the analytical values are verified by the simulation results.LI MingQi RUI Yun 2009Science in China(Series F)2009,52,12:1
20Application of an optimized digital correlation method to planar deformation analysis 显示文摘Sutton M A Mingqi C Peters W H 1986Image and Vision Computing1986,4,3:1
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