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| 1 | 低SO_2氧化率脱硝催化剂的开发显示文摘介绍了SCR脱硝催化剂中V2O5对SO2的氧化及SO2氧化对脱硝催化剂及其下游设备的危害,分析了脱硝催化剂中V2O5对SO2氧化的原理和影响因素,探讨了低SO2氧化率脱硝催化剂开发方面的研究成果。 | 李锋 於承志 张朋 Holger Michaelies | 2010 | 电力科技与环保2010，26，4： | 27 |
| 2 | 高尘烟气脱硝催化剂耐磨性能研究显示文摘分析指出高尘烟气条件下造成脱硝催化剂磨损的主要因素是烟气流速、飞灰硬度以及催化剂表面材料抗屈服强度等,磨损在催化剂顶部和内部通道均有发生。对此,提出了催化剂顶端加固,提高表面材料的抗屈服强度,增加催化剂壁厚以及选择合适的催化剂类型等措施。经过比较得出,平板式催化剂在高尘烟气条件下的耐磨性最强。 | 李锋 於承志 张朋 Holger Michaelis | 2010 | 热力发电2010，39，12： | 23 |
| 3 | 施用不同土壤改良剂对砖红壤酸度的影响显示文摘对砖红壤施用不同的改良剂,经一年的大田试验,测定土壤的活性酸与交换酸研究不同土壤改良剂对酸性土壤酸度的影响。试验结果表明:滤泥单施与石灰单施处理能有效降低土壤的活性酸以及交换性酸的含量,有较好的降低土壤酸度的效果,而施用绿肥、甘蔗渣、羊粪以及羊粪与膨润土混施均不能有效降低土壤的酸度。 | 郇恒福 刘国道 Suzane Berthelsane Michae Webb 李运祥 | 2009 | 热带作物学报2009，30，8： | 16 |
| 4 | Serum adipokines in inflammatory bowel disease显示文摘AIM:To investigate serum adipokine levels in inflammatory bowel disease(IBD)patients before treatment and after achieving clinical remission.METHODS:Serum concentrations of six adipokines(tissue growth factor-β1,adiponectin,leptin,chemerin,resistin,and visfatin)were studied in 40 subjects with active IBD[24 subjects with Crohn’s disease(CD)and in 16 subjects with ulcerative colitis(UC)]before and after three months of therapy with corticosteroids and/or azathioprine.Clinical diagnoses were based on ileocolonoscopy,computed tomography or magnetic resonance enterography and histological examination of mucosal biopsies sampled during endoscopy.Serum levels of adipokines were assessed by an indirect enzyme-linked immunosorbent assay.The control group was comprised of 16 age-and sex-matched healthyvolunteers.RESULTS:Baseline leptin concentrations were significantly decreased in both types of IBD compared to controls(8.0±9.1 in CD and 8.6±6.3 in UC vs 16.5±10.1 ng/mL in controls;P<0.05),and significantly increased after treatment only in subjects with CD(14.9±15.1 ng/mL;P<0.05).Baseline serum resistin concentrations were significantly higher in CD(19.3±12.5ng/mL;P<0.05)and UC subjects(23.2±11.0 ng/mL;P<0.05)than in healthy controls(10.7±1.1 ng/mL).Treatment induced a decrease in the serum resistin concentration only in UC subjects(14.5±4.0 ng/mL;P<0.05).Baseline serum concentrations of visfatin were significantly higher in subjects with CD(23.2±3.2ng/mL;P<0.05)and UC(18.8±5.3 ng/mL;P<0.05)than in healthy controls(14.1±5.3 ng/mL).Treatment induced a decrease in the serum visfatin concentrations only in CD subjects(20.4±4.8 ng/mL;P<0.05).Serum levels of adiponectin,chemerin and tissue growth factor-β1 did not differ between CD and UC subjects compared to healthy controls and also were not altered by anti-inflammatory therapy.Clinical indices of IBD activity did not correlate with adipokine levels.CONCLUSION:IBD modulates serum adipokine levels by increasing resistin and visfatin release and suppressing leptin production. | Marek Waluga Marek Hartleb Grzegorz Boryczka Micha Kukla Krystyna Zwirska-Korczala | 2014 | World Journal of Gastroenterology2014，20，22： | 11 |
| 5 | Reduced interferon antagonism but similar drug sensitivity in Omicron variant compared to Delta variant of SARS-CoV-2 isolates显示文摘Dear Editor,Omicron(B.1.1.529),is a heavily mutated and highly contagious SARS-CoV-2 variant,which is currently causing large outbreaks in many countries.Protection provided by current vaccines is substantially reduced against Omicron.1,2 Moreover,many immunocompromised individuals cannot effectively be protected by vaccines.3 Hence,antiviral therapies will be essential to protect the most vulnerable individuals from severe COVID-19. | Denisa Bojkova Marek Widera Sandra Ciesek Mark N.Wass Martin Michaelis Jindrich Cinatl Jr | 2022 | Cell Research2022，32，3： | 10 |
| 6 | Recent advances in bone regeneration using adult stem cells显示文摘Bone is a highly vascularized tissue reliant on the close spatial and temporal association between bloodvessels and bone cells. Therefore, cells that participate in vasculogenesis and osteogenesis play a pivotal role in bone formation during prenatal and postnatal periods. Nevertheless, spontaneous healing of bone fracture is occasionally impaired due to insufficient blood and cellular supply to the site of injury. In these cases, bone regeneration process is interrupted, which might result in delayed union or even nonunion of the fracture. Nonunion fracture is difficult to treat and have a high financial impact. In the last decade, numerous technological advancements in bone tissue engineering and cell-therapy opened new horizon in the field of bone regeneration. This review starts with presentation of the biological processes involved in bone development, bone remodeling, fracture healing process and the microenvironment at bone healing sites. Then, we discuss the rationale for using adult stem cells and listed the characteristics of the available cells for bone regeneration. The mechanism of action and epigenetic regulations for osteogenic differentiation are also described. Finally, we review the literature for translational and clinical trials that investigated the use of adult stem cells(mesenchymal stem cells, endothelial progenitor cells and CD34+ blood progenitors) for bone regeneration. | Hadar Zigdon-Giladi Utai Rudich Gal Michaeli Geller Ayelet Evron | 2015 | World Journal of Stem Cells2015，7，3： | 9 |
| 7 | 国际抗癫痫联盟心理工作组循证建议:成人和儿童癫痫患者的心理治疗显示文摘社会心理因素和癫痫治疗可能对癫痫患者及其家庭的健康相关生活质量(Health-related quality of life,HRQOL)产生显著影响,临床上广泛关注心理评估和治疗在改善HRQOL和癫痫共病中的作用。因此,国际抗癫痫联盟(ILAE)委托心理工作组,基于其最近对癫痫患者心理治疗的Cochrane回顾证据的评估,制定了相关临床建议。近期关于癫痫患者心理治疗随机对照试验的Cochrane回顾是本文的主要证据来源。为提供具有实用意义的指导,我们根据美国神经病学学会证据水平系统以及推荐分级、评估、开发和评价系统对研究设计进行评级。本文是儿童和成人心理学家、神经病学家、精神病学家和神经精神病学家进行国际合作的顶点。ILAE执行委员会审查并批准了这一进程和结论。心理干预的最强证据被确定为最常见的心理健康问题,包括抑郁症、神经认知障碍和药物依从性。针对提高HRQOL和依从性以及减少共病症状(焦虑、抑郁)的心理干预应纳入癫痫综合护理中。一系列的心理策略(如认知行为疗法和正念疗法)为提升癫痫患者生活质量带来希望,也给癫痫临床工作者提供了治疗癫痫共病、应对挑战的临床建议。 | Rosa Michaelis Venus Tang Laura H Goldstein 肖英凤(译) 童馨(审) 慕洁(审) | 2019 | 癫痫杂志2019，5，4： | 9 |
| 8 | 为不确定的未来实施洪水风险管理战略:荷兰,与莱茵河洪水共生存显示文摘无论从经济还是从自然保护角度,冲积平原和三角洲的社会压力都很大。随着经济的发展及大坝增高,由于预期的损失上升和更深的洪水,洪水风险在逐渐增加。全球变化,社会需求变化了,人们的观念也变化了,需要修订长期的洪水风险管理战略。而修订洪水风险管理战略应以柔性战略替代过去以加高大坝为主的刚性战略。柔性战略为主的洪水风险管理就意味着允许洪水临时性大面积泛滥,通过改变土地利用方式减少洪水灾害损失。这样的战略是基于风险管理和'与洪水共生存'的理念提出的,完全替代了过去的灾害控制观念。荷兰三角洲地区是世界人口密度最大区域之一,在这里,灵活的柔性洪水风险管理战略水文功能和'可持续的标准'被详细阐述和评估。 | Frans Klijn Michaёl vanBuuren Sabine A.M.vanRooij 石秋池 | 2004 | AMBIO-人类环境杂志2004，33，3： | 9 |
| 9 | EO-1 Hyperion数据的预处理、特征提取和岩性填图研究(英文)显示文摘EO-1 Hyperion传感器是第一个可以获取可见光与近红外以及短波红外波长范围光谱信息的星载高光谱传感器。本文以美国最早的金矿采矿区之一,加利福尼亚州东南巧克力山的Rainbow金矿区作为研究案例,探讨了Hyperion数据的预处理方法,专题信息提取与填图,评估了Hyperion高光谱数据在识别与金矿有关的岩性类型的应用价值。结果表明,本文所提出的Hyperion数据预处理方法是有效的,MNF方法能有效用于Hyperion数据维数的降低和数据冗余的去除以及分类特征的提取。最大似然分类器能够有效地从Hyperion高光谱数据中提取与金矿相关的重要岩体信息,所得到的岩性单元与地质图上对应的岩性分布具有很好的一致性。岩体分类的总精度为86%。该研究表明,Hyperion高光谱数据能够很好识别有细微光谱差别的岩性,因而在地质学研究与找矿领域有着良好的应用前景。 | 张显峰 PAZNER Micha | 2007 | 中国图象图形学报2007，12，6： | 8 |
| 10 | 平板式催化剂在电厂高尘、高砷燃煤烟气脱硝中的应用显示文摘从平板式脱硝催化剂结构的角度出发,分析了平板式催化剂的特点,以某脱硝工程的催化剂选型和设计为实例,论述了平板式催化剂在电厂高尘、高砷燃煤烟气条件对脱硝的适应性。 | 李锋 於承志 张朋 Holger Michaelis | 2010 | 华电技术2010，32，5： | 8 |
| 11 | 艾滋病合并隐球菌脑膜炎18例临床分析显示文摘目的 提高对艾滋病 (AIDS)合并隐球菌脑膜炎的认识。方法 对赤道几内亚巴塔地区医院 18例AIDS合并隐球菌脑膜炎患者进行临床综合分析。结果 18例AIDS合并隐球菌脑膜炎患者的临床主要表现为 :发热、剧烈头痛、极度乏力、肢体痛、脑膜刺激征及消瘦与脱水等。脑脊液 (CSF)培养均为新型隐球菌生长 ;涂片及隐球菌多糖荚膜抗原 (ELISA法 )检测的阳性率分别为 77 8% (14/ 18) ,94 4% (17/ 18)。结论 隐球菌脑膜炎为AIDS常见机会性感染及主要致死病因之一。 | 王文琦 Micha ST Justino OB | 2000 | 中国实用内科杂志2000，20，11： | 8 |
| 12 | Oxidative stress factors in Parkinson's disease显示文摘Parkinson's disease(PD) is the second most common cause of neurodegeneration.Over the last two decades, various hypotheses have been proposed to explain the etiology of PD.Among these is the oxidant-antioxidant theory, which asserts that local and systemic oxidative damage triggered by reactive oxygen species and other free radicals may promote dopaminergic neuron degeneration.Excessive reactive oxygen species formation, one of the underlying causes of pathology in the course of PD has been evidenced by various studies showing that oxidized macromolecules including lipids, proteins, and nucleic acids accumulate in brain tissues of PD patients.DNA oxidation may produce various lesions in the course of PD.Mutations incurred as a result of DNA oxidation may further enhance reactive oxygen species production in the brains of PD patients, exacerbating neuronal loss due to defects in the mitochondrial electron transport chain, antioxidant depletion, and exposure to toxic oxidized dopamine.The protein products of SNCA, PRKN, PINK1, DJ1, and LRRK2 genes are associated with disrupted oxidoreductive homeostasis in PD.SNCA is the first gene linked with familial PD and is currently known to be affected by six mutations correlated with the disorder: A53T, A30P, E46K, G51D, H50Q and A53E.PRKN encodes Parkin, an E3 ubiquitin ligase which mediates the proteasome degradation of redundant and disordered proteins such as glycosylated α-synuclein.Over 100 mutations have been found among the 12 exons of PRKN.PINK1, a mitochondrial kinase highly expressed in the brain, may undergo loss of function mutations which constitute approximately 1–8% of early onset PD cases.More than 50 PD-promoting mutations have been found in PINK1.Mutations in DJ-1, a neuroprotective protein, are a rare cause of early onset PD and constitute only 1% of cases.Around 20 mutations have been found in DJ1 among PD patients thus far.Mutations in the LRRK2 gene are the most common known cause of familial autosomal dominant PD and sporadic PD.Treatment of PD patients, especially in the advanced stages of the disease, is very difficult.The first step in managing progressive PD is to optimize dopaminergic therapy by increasing the doses of dopamine agonists and L-dopa.The next step is the introduction of advanced therapies, such as deep brain stimulation.Genetic factors may influence the response to L-dopa and deep brain stimulation therapy and the regulation of oxidative stress.Consequently, research into minimally invasive surgical interventions, as well as therapies that target the underlying etiology of PD is warranted. | Jolanta Dorszewska Marta Kowalska Michał Prendecki Thomas Piekut Joanna Kozłowska Wojciech Kozubski | 2021 | Neural Regeneration Research2021，16，7： | 7 |
| 13 | Direct, remote and combined ischemic conditioning in liver surgery显示文摘Liver ischemia-reperfusion injury is a major cause of postoperative liver dysfunction,morbidity and mortality following liver resection and transplantation.Ischemic conditioning has been shown to ameliorate ischemiareperfusion injury in small animal models.It can be applied directly or remotely when cycles of ischemia and reperfusion are applied to a distant site or organ.Considering timing of the procedure,different protocols are available.Ischemic preconditioning refers to that performed before the duration of ischemia of the target organ.Ischemic perconditioning is performed over the duration of ischemia of the target organ.Ischemic postconditioning applies brief episodes of ischemia at the onset of reperfusion following a prolonged ischemia.Animal studies pointed towards suppressing cytokine release,enhancing the production of hepatoprotective adenosine and reducing liver apoptotic response as the potential mechanisms responsible for the protective effect of direct tissue conditioning.Interactions between neural,humoral and systemic pathways all lead to the protective effect of remote ischemic preconditioning.Despite promising animal studies,none of the aforementioned protocols proved to be clinically effective in liver surgery with the exception of morbidity reduction in cirrhotic patients undergoing liver resection.Further human clinical trials with application of novel conditioning protocols and combination of methods are warranted before implementation of ischemic conditioning in day-to-day clinical practice. | Rafał Stankiewicz Michał Grąt | 2021 | World Journal of Hepatology2021，13，5： | 5 |
| 14 | Factors associated with irritable bowel syndrome symptoms in hemodialysis patients显示文摘AIM: To investigate clinical characteristics associated with the presence of irritable bowel syndrome (IBS) symptoms in hemodialysis (HD) patients.METHODS: This was a cross-sectional study. A questionnaire based on the Bowel Disease Questionnaire that records gastrointestinal symptoms was given to 294 patients in 4 dialysis centers. A total of 196 (67%) subjects returned the survey. A multivariable logistic regression model was used to identify factors significantly associated with IBS symptoms. RESULTS: Symptoms compatible with IBS were present in 27 (13.8%) subjects and independently associated with low post-dialysis serum potassium [OR = 0.258, 95% CI (0.075-0.891), P = 0.032], paracetamol use [OR = 3.159, 95% CI (1.214-8.220), P = 0.018], and Kidney Disease Quality of Life (KDQOL) cognitive function score [OR = 0.977, 95% CI (0.956-0.999), P = 0.042]. Univariate regressions were also performed and the reported significance is for multivariate analysis. No association was detected for age, gender, depressed mood, smoking (present or past), body mass index, albumin level, Kt/V, sodium preor post-dialysis level, change in potassium level during HD, proton pump inhibitor or H2 blocker use, aspirin use, residual diuresis, hepatitis B or C infection, diabetes mellitus, marital status and education level. CONCLUSION: This study examined potential risk factors for symptoms compatible with IBS in HD patients and identified an association with paracetamol use, post-dialysis potassium level and KDQOL-cognitive function score. | Bartosz Fiderkiewicz Alicja Rydzewska-Rosoowska Micha Myliwiec Magdalena Birecka Bozenna Kaczanowska Grazyna Rydzewska Andrzej Rydzewski | 2011 | World Journal of Gastroenterology2011，17，15： | 5 |
| 15 | Thickness determination of MoS2,MoSe2,WS2 and WSe2 on transparent stamps used for deterministic transfer of 2D materials显示文摘Here,we propose a method to determine the thickness of the most common transition metal dichalcogenides (TMDCs) placed on the surface of transparent stamps,used for the deterministic placement of two-dimensional materials,by analyzing the red,green and blue channels of transmission-mode optical microscopy images of the samples.In particular,the blue channel transmittance shows a large and monotonic thickness dependence,making it a very convenient probe of the flake thickness.The method proves to be robust given the small flake-to-flake variation and the insensitivity to doping changes of MoS2.We also tested the method for MoSe2,WS2 and WSe2.These results provide a reference guide to identify the number of layers of this family of materials on transparent substrates only using optical microscopy. | Najme S. Taghavi Patricia Gant Peng Huang Iris Niehues Robert Schmidt Steffen Michaelis de Vasconcellos Rudolf Bratschitsch Mar Garcia-Hernandez Riccardo Frisenda Andres Castellanos-Gomez | 2019 | Nano Research2019，12，7： | 3 |
| 16 | Evaluating the impact of thermostat control strategies on the energy flexibility of residential buildings for space heating显示文摘Buildings can be operated in an energy-flexible manner while respecting occupant thermal comfort.This energy flexibility of building operations,both in time and quantity,can be harnessed by the electrical grid for load balancing.In the context of smart grid and intelligent buildings,the concept of energy flexibility in buildings broadens the existing demand management thinking from the top-down one-way control to two-way communications.This paper,extending studies on thermostat controls of heating and air conditioning systems for demand response,evaluates the impact of different control schemes on the energy flexibility of residential buildings.Two control strategies,Model Predictive Control(MPC)and Rule-Based Control(RBC),are investigated for a space heating system using co-simulation studies.Four indicators are introduced and adapted from the literature to assess the control performances of the strategies.Simulation results show that different flexibility indicators favour different control strategies in this case study.For demand response events of four hours,the MPC strategy presents two to three times of flexible energy than that of RBC.MPC also delivers 20%more of maximum power reduction during the events against RBC.The RBC strategy,on the other hand,is twice of MPC for flexible energy efficiency.This evaluation work can be beneficial to guide the control system design of new buildings or control retrofits of existing buildings that consider better grid-building interactions for the future. | Kun Zhang Michaël Kummert | 2021 | Building Simulation2021，14，5： | 3 |
| 17 | 颈椎的眩晕试验能预防手法的合并症吗显示文摘颈椎和椎动脉关系密切,任何一方有先天性异常或病变时椎动脉就容易受损。这种损伤可由于对颈部施行强力手法所致,头颈部的种种生理性运动也可引起颈动脉的机械性压迫。这些都可导致椎底动脉机能不全而伴随许多症状,最值得注意的是眩晕。颈椎手法治疗的潜在危险已有大量的记载。文献报告在1934~1990年间,用此手法后已发生了116例血管意外,死亡24人。 | Michaeli A 陈泗才 | 1993 | 国外医学(物理医学与康复学分册)1993，13，1： | 3 |
| 18 | Impact of sodium glucose cotransporter-2 inhibitors on liver steatosis/fibrosis/inflammation and redox balance in non-alcoholic fatty liver disease显示文摘BACKGROUND Sodium glucose cotransporter-2 inhibitors(SGLT2-I)are the most recently approved drugs for type 2 diabetes(T2D).Recent clinical trials of these compounds reported beneficial cardiovascular(CV)and renal outcomes.A major cause of vascular dysfunction and CV disease in diabetes is hyperglycemia associated with inflammation and oxidative stress.Pre-clinical studies demonstrated that SGLT2-I reduce glucotoxicity and promote anti-inflammatory effects by lowering oxidative stress.AIM To investigate the effects of SGLT2-I on markers of oxidative stress,inflammation,liver steatosis,and fibrosis in patients of T2D with non-alcoholic fatty liver disease(NAFLD).METHODS We referred fifty-two consecutive outpatients treated with metformin monotherapy and exhibiting poor glycemic control to our centre.We introduced the outpatients to an SGLT2-I(dapagliflozin,empagliflozin,or canagliflozin;n=26)or a different hypoglycemic drug[other glucose-lowering drugs(OTHER),n=26].We evaluated circulating interleukins and serum hydroxynonenal(HNE)-or malondialdehyde(MDA)-protein adducts,fatty liver index(FLI),NAFLD fibrosis score,aspartate aminotransferase(AST)/alanine aminotransferase(ALT)ratio,AST-to-platelet-ratio index(APRI),and fibrosis-4 on the day before(T0)and following treatment for six months(T1).We also performed transient elastography at T0 and T1.RESULTS Add-on therapy resulted in improved glycemic control and reduced fasting blood glucose in both groups.Of note,following treatment for six months,a reduction of FLI and APRI,as well as of the FibroScan result,was reported in patients treated with SGLT2-I,but not in the OTHER group;furthermore,in the SGLT2-I group,we reported lower circulating levels of interleukin(IL)-1β,IL-6,tumor necrosis factor,vascular endothelial growth factor,and monocyte chemoattractant protein-1,and higher levels of IL-4 and IL-10.We did not observe any modification in circulating interleukins in the OTHER group.Finally,serum HNE-and MDA-protein adducts decreased significantly in SGLT2-I rather than OTHER patients and correlated with liver steatosis and fibrosis scores.CONCLUSION The present data indicate that treatment with SGLT2-I in patients with T2D and NAFLD is associated with improvement of liver steatosis and fibrosis markers and circulating pro-inflammatory and redox status,more than optimizing glycemic control. | Francesco Bellanti Aurelio Lo Buglio MichałDobrakowski Aleksandra Kasperczyk Sławomir Kasperczyk Palok Aich Shivaram P Singh Gaetano Serviddio Gianluigi Vendemiale | 2022 | World Journal of Gastroenterology2022，28，26： | 3 |
| 19 | 临终关怀与安乐死的整合:比利时模式的实验与回答显示文摘通过《生命伦理学探究杂志》顾问编辑Michael Ashby提出的一系列问题对比利时临终照护模式的构成进行分析。分析了关于比利时姑息治疗与安乐死之间互补及协同关系。在比利时模式的整合临终护理中,安乐死是姑息治疗途径的终点。安乐死合法化制定于2002年,而后,众多姑息治疗服务兴起。随着公众对卫生保健机构信心的提升和社会态度的广泛进步,对姑息治疗和安乐死的支持水平明显提高,这将使二者的协同发展成为可能。虽然目前比利时模式仍表现出一些缺陷,但一些解决方案正在制定过程中。 | Jan L.Bernheim Wim Distelmans Arsène Mullie Micha el A.Ashby 于磊 | 2014 | 医学与哲学(A)2014，35，12： | 3 |
| 20 | Total factor productivity differences: Appropriate technology vs. efficiency显示文摘 | Micha? Jerzmanowski | 2007 | European Economic Review2007，，8： | 2 |
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