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| 1 | Increased kidney xanthine oxidoreductase activity in salt-induced experimental hypertension显示文摘 | Laakso J Mervaala E Himberg J | 1998 | Hypertension1998，32，： | 1 |
| 2 | Quantitative MRI of the hippocamjpus and amygdala in severe depression显示文摘 | Mervaala E Fohr J Kononen M | 2000 | Psychol Med2000，30，6： | 1 |
| 3 | Quantitative MRI of the hippocampus and amygdala in severe depression 显示文摘 | Mervaala E Fohr J Kononen M | 2000 | PsycholMed2000，30，1： | 1 |
| 4 | Quantitative MRI of the hippocampus and amygdala in severe depression显示文摘 | Mervaala E Fohr J Kononen M | 2000 | Psychol Med2000，30，1： | 1 |
| 5 | Angiotensin Ⅱ and vascular inflammation显示文摘 | Cheng ZJ Vapaatalo H Mervaala E | 2005 | Med Sci Monit2005，11，6： | 1 |
| 6 | Angiotensin Ⅱ and vascular inflammation显示文摘 | Cheng ZJ Vapaatalo H Mervaala E | 2005 | Med Sci Monit2005，11，6： | 1 |
| 7 | Effect of bosentan on NF-Kappa B, inflammation , and tissue factor in angiotensin I-induced end-organ damage 显示文摘 | Muller DN Mervaala EM Schmidt F | 2000 | Hypertension2000，36，： | 1 |
| 8 | Diet enrichment with calcium and magnesium enhances the cholesterol-lowering effect of plant sterols in obese Zucker rats 显示文摘 | Vaskonen T Mervaala E Seppanen-Laakso T | 2001 | Nutr Metab Cardiovasc Dis2001，11，3： | 1 |
| 9 | Cutaneous electricalstimulation treatment in unresolved facial nerve paralysis:anexploratory study显示文摘 | Hyvarinen A Tarkka IM Mervaala E | 2008 | Am J Phys Med Rehabilit2008，87，12： | 1 |
| 10 | Metabolomic changes in fatty liver can be modified by dietary protein and calcium during energy restriction显示文摘AIM: To characterise the effect of energy restriction (ER) on liver lipid and primary metabolite profile by using metabolomic approach. We also investigated whether the effect of energy restriction can be further enhanced by modif ication of dietary protein source and calcium. METHODS: Liver metabolomic profile of lean and obese C57Bl/6J mice (n = 10/group) were compared with two groups of weight-reduced mice. ER was performed on control diet and whey protein-based high-calcium diet (whey + Ca). The metabolomicanalyses were performed using the UPLC/MS based lipidomic platform and the HPLC/MS/MS based primary metabolite platform. RESULTS: ER on both diets significantly reduced hepatic lipid accumulation and lipid droplet size, while only whey + Ca diet significantly decreased blood glucose (P < 0.001) and serum insulin (P < 0.01). In hepatic lipid species the biggest reduction was in the level of triacylglycerols and ceramides while the level of cholesterol esters was significantly increased during ER. Interestingly, diacylglycerol to phospholipid ratio, an indicator of relative amount of diabetogenic diglyceride species, was increased in the control ER group, but decreased in the whey + Ca ER group (P < 0.001, vs obese). ER on whey + Ca diet also totally reversed the obesity induced increase in the relative level of lipotoxic ceramides (P < 0.001, vs obese; P > 0.05, vs lean). These changes were accompanied with up-regulated TCA cycle and pentose phosphate pathway metabolites. CONCLUSION: ER-induced changes on hepatic metabolomic profile can be significantly affected by dietary protein source. The therapeutic potential of whey protein and calcium should be further studied. | Taru K Pilvi Tuulikki Seppnen-Laakso Helena Simolin Piet Finckenberg Anne Huotari Karl-Heinz Herzig Riitta Korpela Matej Orei Eero M Mervaala | 2008 | World Journal of Gastroenterology2008，14，28： | 1 |
| 11 | Sodium intake and hypertension显示文摘 | KARPPANEN H MERVAALA E | 2006 | Prog Cardiovasc Dis2006，49，2： | 1 |
| 12 | Effect ofbosentan on NF-kappaB inflammation and tissue factorin angiotensinⅡ-induced endorgan damage显示文摘 | Muller DN Mervaala EM Schmidt F | 2000 | Hyper-tension2000，36，： | 1 |
| 13 | Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure-and cholesterol-lowering effects显示文摘 | Park JK Muller DN Mervaala EM | 2000 | Kidney Int2000，58，4： | 1 |
| 14 | Enhanced attention-dependent auditory processing by electroconvulsive therapy in psychotic depression显示文摘 | Nurmlinen M Valkonen-Korhonen M Mervaala E | 2005 | J ECT2005，21，1： | 1 |
| 15 | Increased kidney xanthine oxidoreductase activity in salt-induced experimental hypertension显示文摘 | Laakso J Mervaala E Himberg JJ Teravainen TL Karppanen H Vapaatalo H | 1998 | Hypertension1998，32，： | 1 |
| 16 | Angiotensin Ⅱ and vascular inflammation显示文摘 | Vapaatalo H Mervaala E | 2005 | Med Sci Monit2005，11，6： | 1 |
| 17 | Angiotensin II and vascular inflammation 显示文摘 | Cheng Z J Vapaatalo H Mervaala E | 2005 | Med Sci Monit2005，11，6： | 1 |
| 18 | Cerivastatin prevents angiotensin Ⅱ-induced renal injury independent of blood pressure-and cholesterollowering effects显示文摘 | Park JK Muller DN Mervaala EM | 2000 | Kidney Int2000，58，4： | 1 |
| 19 | Quantitative MRI of the hippocampus and amygdala in severe depression 显示文摘 | Folhr J Kononen M | 2000 | Psychological Medicine2000，30，1： | 1 |
| 20 | Angiotensin Ⅱ (AT1) receptor blockade reduces vascular tissue factor in angiotensin Ⅱ-induced cardiac vasculopathy显示文摘 | Müller DN Mervaala EM Dechend R | 2000 | Am J Pathol2000，157，19： | 1 |
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