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| 1 | Spontaneous fungal peritonitis: Micro-organisms, management and mortality in liver cirrhosis-A systematic review显示文摘BACKGROUND Spontaneous peritonitis is an infection of ascitic fluid without a known intraabdominal source of infection. spontaneous fungal peritonitis (SFP) is a potentially fatal complication of decompensated cirrhosis, defined as fungal infection of ascitic fluid in the presence of ascitic neutrophil count of greater than 250 cells/mL. AIM To determine the prevalence of fungal pathogens, management and outcomes (mortality) of SFP in critically ill cirrhotic patients. METHODS Studies were identified using PubMed, EMBASE, Cochrane Central Register of Controlled Trials and Scopus databases until February 2019. Inclusion criteria included intervention trials and observation studies describing the association between SFP and cirrhosis. The primary outcome was in-hospital, 1-mo, and 6- mo mortality rates of SFP in cirrhotic patients. Secondary outcomes were fungal microorganisms identified and in hospital management by anti-fungal medications. The National Heart, Lung and Blood Institute quality assessment tools were used to assess internal validity and risk of bias for each included study. RESULTS Six observational studies were included in this systematic review. The overall quality of included studies was good. A meta-analysis of results could not be performed because of differences in reporting of outcomes and heterogeneity of the included studies. There were 82 patients with SFP described across all the included studies. Candida species, predominantly Candida albicans was the fungal pathogen in majority of the cases (48%-81.8%) followed by Candida krusei (15%- 25%) and Candida glabrata (6.66%-20%). Cryptococcus neoformans (53.3%) was the other major fungal pathogen. Antifungal therapy in SFP patients was utilized in 33.3% to 81.8% cases. The prevalence of in hospital mortality ranged from 33.3% to 100%, whereas 1-mo mortality ranged between 50% to 73.3%. CONCLUSION This systematic review suggests that SFP in end stage liver disease patient is associated with high mortality both in the hospital and at 1-mo, and that antifungal therapy is currently underutilized. | Tooba Tariq Furqan B Irfan Mehdi Farishta Brian Dykstra Eric Martin Sieloff Archita P Desai | 2019 | World Journal of Hepatology2019，11，7： | 7 |
| 2 | Effect of Combustor Geometry on Performance of Airblast Atomizer Under Sub-atmos- pheric Conditions显示文摘 | GRECH N MEHDI A ZACHOS P K | 2012 | Engineering Applications of Computational Fluid Mechanics2012，6，2： | 1 |
| 3 | In vitro cytotoxicity and phototoxicity of N-piperazinyl quinolone derivatives with a 2-thienyl group显示文摘 | Abbas P Alireza F Mehdi H | | 0，，： | 1 |
| 4 | The effect of different dispersants on the physical properties of nano CoAl2 04 ceramic ink-jet ink 显示文摘 | Masoud P Atasheh S G Mehdi G | 2015 | Ceramics International2015，41，： | 1 |
| 5 | Robustness and Optimality of Linear Quadratic Controller for Uncertain Systems显示文摘 | Mehdi D Mohammed A H Francois P | 1996 | Automatic1996，32，7： | 1 |
| 6 | Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy 显示文摘 | Mehdi UF Adams-Huet B Raskin P | 2009 | J Am Soc Neph rol2009，20，12： | 1 |
| 7 | Prediction of the height of destressed zone above the mined panel roof in longwall coal mining显示文摘 | Abbas Majdi Feni P Hassani Mehdi Yousef Nasiri | 2012 | International Journal of Coal Geology2012，98，1： | 1 |
| 8 | Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy显示文摘 | Mehdi UF Adams-Huet B Raskin P | 2009 | J Am Soc Nephrol2009，20，12： | 1 |
| 9 | Concrete creep and shrinkage prediction from short-term tests 显示文摘 | Rasko P O Mehdi S Z | 1996 | ACI Materials Journal1996，93，2： | 1 |
| 10 | Investigation of particle size and amount of alumina on microstructure and mechanical properties of matrix composite made by power metallurgy显示文摘 | Mehdi R Nader P Naser E | 2010 | Materials Science and Engineering A2010，527，45： | 1 |
| 11 | Electrical remodeling of cardiac myocytes from micewith heart failure due to the overexpression of tumornecrosis factor-α显示文摘 | PETKOVA-KIROVA P S GURSOY E MEHDI H | 2006 | Am J Physiol Heart Circ Physi-ol2006，290，： | 1 |
| 12 | Improved nonrelapse mortality and infection rate with lower dose of antithymocyte globulin in patients undergoing reduced-intensity conditioning allogeneic transplantation for hematologic malignancies显示文摘 | MEHDI H WILLIAM B GARY P | 2009 | Biol Blood Marrow Transplant2009，15，： | 1 |
| 13 | Amberlyst 15 supported nitrosonium ion as an efficient reagent for regeneration of carbonyl compounds from oximes, hydrazones and semicarbazones 显示文摘 | Enquist P A Mehdi N Masoud M | 2006 | Reactive and functional polymers2006，66，： | 1 |
| 14 | Addition of angiotensin receptor blockade or mineralocorticoid antagonism to maximal angiotensin-converting enzyme inhibition in diabetic nephropathy显示文摘 | Mehdi UF Adams-Huet B Raskin P | 2009 | J Am Soc Yephrol2009，20，12： | 1 |
| 15 | A wideband w-band receiver front-end in 65-nm CMOS显示文摘 | Mehdi Khanpour Keith W Tang Patrice Garcia Sorin P Voinigescu | 2008 | IEEE Journal of Solid-State Circuits2008，43，8： | 1 |
| 16 | Quadratic controller for uncertain systems 显示文摘 | Mehdi D Mohammed A H Francois P | 1996 | Automatica1996，，32： | 1 |
| 17 | An evaluation of magneto rheological dampers for controlling gun recoil dynamics 显示文摘 | Mehdi A James C P | 2001 | Shock and Vibration2001，8，： | 1 |
| 18 | Electrical remodeling of cardiac myocytes from mice with heart failure due to the overexpression of tumor necrosis factor-a 显示文摘 | PETKOVA-KIROVA P S GURSOY E MEHDI H | 2006 | Am J Physiol Heart Circ Physiol2006，290，： | 1 |
| 19 | Robustness and Optimality of Linear Quadratic Control for Uncertain Systems显示文摘 | Mehdi D Mohammed A H Francois P | 1996 | Autonatic1996，32，7： | 1 |
| 20 | The Walking Behaviour of Pedestrian Social Groups and its Impact on Crowd Dynamics 显示文摘 | Mehdi M Niriaska P Simon G | 2010 | PLoS One(S1932-6203)2010，5，10： | 1 |
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