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| 1 | The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia显示文摘Objective: To verify possible associations between adenosine aminohydrolase(ADA) and AMP-aminohydrolase(AMPDA) to E3 SUMO-protein ligase NSE2(NSMCE2) in patients with renal stones. And to isolate, purify and characterize ADA in patients with renal stones and healthy group.Methods: A total of 60 renal stones patients and 50 control were enrolled in a case-control study. The blood urea, creatinine, uric acid, protein, albumin, ADA and AMPDA were measured by colorimetric tests. The serum NSMCE2 was measured by ELISA.Results: Serum ADA, AMPDA and specii c activity of enzymes showed signii cant decrease(P < 0.05) in patients with renal stones compared to control group, mean levels of sera NSMCE2 and uric acid had a signii cant increase(P < 0.01 and P < 0.05, respectively) in patients compared to control group.Conclusions: The present study suggests that ADA, AMP deaminase and NSMCE2 can be used as a indicator to monitor the DNA damage and inl ammation disorders in the patients with kidney stones. | Faridah Yusof Atheer Awad Mehde Wesen Adel Mehdi Hamid Ghazali Azlina Abd Rahman | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，6： | 3 |
| 2 | Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver regulation by TNF-alpha and TGF-beta l显示文摘 | KNITYEL T MEHDE M KOBOLD D | 1999 | J Hepatol1999，30，1： | 1 |
| 3 | Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver:regulation by TNF-alpha and TGFbetal显示文摘 | nittel T Mehde M Kobold D | 1999 | J Hepatol1999，30，1： | 1 |
| 4 | Expression patterns of matrix metelloproteinases and their inhibitors in parenchymal and nonparenchymal cells of rat livers :regulation by TNF alfa and TGF beta显示文摘 | KNITTEL T MEHDE M KOBLOD D | 1999 | J Hepatol1999，30，1： | 1 |
| 5 | The incidence of postoperative pain after canal preparation of open teeth using two irrigation regimes显示文摘 | Mehd Sulong MZ | 1989 | Int Endod J1989，22，5： | 1 |
| 6 | Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and nonparencymal cells of rat liver: regulation by TNF-alpha and TGF-beta 1 显示文摘 | Knittel L Mehde M Kobold D | 1999 | J Hepatol1999，30，1： | 1 |
| 7 | Expression of matrix metalloproteinases and their inhibitors during hepatic tissue repair in the rat显示文摘 | Knittel T Mehde M Grundmann A | 2000 | Histochem Cell Biol2000，113，6： | 1 |
| 8 | Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver:regulation by TNF-alpha and TGF-beta 1显示文摘 | Knittel T Mehde M Kobold D | 1999 | J Hepatol1999，30，1： | 1 |
| 9 | Effects of Nephrolithiasis on Serum DNase(Deoxyribonuclease Ⅰ and Ⅱ) Activity and E3 SUMO-Protein Ligase NSE2(NSMCE2) in Malaysian Individuals显示文摘Objective Nephrolithiasis is one of the most common disorders of the urinary tract. The aim of this study was to examine a possible relationship between DNase Ⅰ/Ⅱ activity and E3 SUMO-protein ligase NSE2 in the sera of nephrolithiasis patients to evaluate the possibility of a new biomarker for evaluating kidney damage. Methods Sixty nephrolithiasis patients and 50 control patients were enrolled in a case-control study. Their blood urea, creatinine, protein levels and DNase Ⅰ/Ⅱ activity levels were measured by spectrometry. Serum NSMCE2 levels were measured by ELISA. Blood was collected from patients of the government health clinics in Kuantan-Pahang and fulfilled the inclusion criteria. Results The result indicated that mean levels of sera NSMCE2 have a significantly increase(P<0.01) in patients compared to control group. Compared with control subjects, activities and specific activities of serum DNase Ⅰ and Ⅱ were significantly elevated in nephrolithiasis patients(P<0.01). Conclusion This study suggests that an increase in serum concentrations of DNase Ⅰ/Ⅱ and E3 SUMO-protein ligase NSE2 level can be used as indicators for the diagnosis of kidney injury in patients with nephrolithiasis. | Faridah Yusof Atheer Awad Mehde Wesen Adel Mehdi Raha Ahmed Raus Hamid Ghazali Azlina Abd Rahman | 2015 | Biomedical and Environmental Sciences2015，28，9： | 1 |
| 10 | Expression patterns of matrix metelloproteinases and their inhibitors in parenchymal and nonparenchymal cells of rat livers:regulation by TNF alfa and TGF beta 显示文摘 | Knittel T Mehde M Koblod D | 1999 | J Hepatol1999，30，1： | 1 |
| 11 | Expression patterns of matrix metalloproteinases and their inhibitors in parenehymal and non-parenchymal cells of rat liver: regulation by TNF-alpha and TGF-betal 显示文摘 | Knittel T Mehde M Kobold D | 1999 | Hepatology1999，30，1： | 1 |
| 12 | Expression and regulation of cell adhesion molevules by hepatic atellate cells (HSC) of rat liver:involvment of HSC in recruitment of onflammatory cells during hepatic tissue repair显示文摘 | Knittel T Dinter C Kobold D Neubauer K Mehde M Eichhorst S Ramadori G | 1999 | Am J PATHOL1999，154，： | 1 |
| 13 | Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non -- parenchymal ceils of rat liver: regulation by TNF--alpha and TGF--betal显示文摘 | Knittel T Mehde M Kobold D | 1999 | J Hepatol1999，30，1： | 1 |
| 14 | 显示文摘 | Mehde M Kobold D | 1999 | Hepatol1999，30，： | 1 |
| 15 | Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-paten chymal cells of rat liver,regulation by TNF-alpha and TGF-betal显示文摘 | Kniael T Mehde M Kobold D | 1999 | J Hepatol1999，30，： | 1 |
| 16 | Expression patterns of matrix metaloproteinases and their inhibitors in parenchymal and nonparenchymal cells of rat liver:regulation by TNF-α and TGF-β显示文摘 | Knittel T Mehde M Kobokd D Saile B Dinter C Ramadori G | 1999 | J Hepatol1999，30，1： | 1 |
| 17 | The incidence of postoperative pain after canal preparation of open teeth using two irrigation regimes显示文摘 | Mehd Sulong MZ | 1989 | Int Endod J1989，22，： | 1 |
| 18 | Expression of matrix metalloproteinases and their inhibitors during hepatic tissue repair in the rat显示文摘 | Knittel T Mehde M Grundmann A | 2000 | Histochem Cell Biol2000，113，6： | 1 |
| 19 | Expression of matrix metalloprotelnases and their inhibltors during hepatic tissue repair in the rat 显示文摘 | Thomas Knittel Mirko Mehde Anka Grundmann | 2000 | Histochem Cell Biol2000，113，： | 1 |
| 20 | Expression of matrix metalloproteinases and their inhibitors during hepatic tissue repair in the rats显示文摘 | Knittel T Mehde M Grundmann A | 2000 | Histochem Cell Biol2000，113，6： | 1 |
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