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| 1 | Gastroesophageal reflux disease: Important considerations for the older patients显示文摘Gastroesophageal reflux disease (GERD) is the most common upper gastrointestinal disorder seen in the elderly. The worldwide incidence of GERD is increasing as the incidence of Helicobacter pylori is decreasing. Although elderly patients with GERD have fewer symptoms, their disease is more often severe. They have more esophageal and extraesophageal complications that may be potentially life threatening. Esophageal complications include erosive esophagitis, esophageal stricture, Barrett's esophagus and adenocarcinoma of the esophagus. Extraesophageal complications include atypical chest pain that can simulate angina pectoris; ear, nose, and throat manifestations such as globus sensation, laryngitis, and dental problems; pulmonary problems such as chronic cough, asthma, and pulmonary aspiration. A more aggressive approach may be warranted in the elderly patient, because of the higher incidence of severe complications. Although the evaluation and management of GERD are generally the same in elderly patients as for all adults, there are specific issues of causation, evaluation and treatment that must be considered when dealing with the elderly. | Maxwell M Chait | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，12： | 22 |
| 2 | Lower gastrointestinal bleeding in the elderly显示文摘Lower gastrointestinal bleeding(LGIB) is an important worldwide cause of morbidity and mortality in the elderly.The incidence of LGIB increases with age and corresponds to the increased incidence of specific gastrointestinal diseases that have worldwide regional variation,co-morbid diseases and polypharmacy.The evaluation and treatment of patients is adjusted to the rate and severity of hemorrhage and the clinical status of the patient and may be complicated by the presence of visual,auditory and cognitive impairment due to age and co-morbid disease.Bleeding may be chronic and mild or severe and life threatening,requiring endoscopic,radiologic or surgical intervention.Colonoscopy provides the best method for evaluation and treatment of patients with LGIB.There will be a successful outcome of LGIB in the majority of elderly patients with appropriate evaluation and management. | Maxwell M Chait | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，5： | 3 |
| 3 | Wind tunnel study of the resilience of three fungal crusts to particle abrasion during aeolian sediment transport 显示文摘 | Neuman C M Maxwell C | 1999 | Catena1999，38，2： | 1 |
| 4 | Chrysoeriol and luteolin released from alfalfa seeds induce nod genes in Rhizobium meliloti显示文摘 | Hartwing U A Maxwell C A Joseph C M | 1990 | Plant Physiology1990，92，： | 1 |
| 5 | Stable implicit motor processes despite aerobic locomotor fatigue显示文摘 | MASTERS R S W POOLTON J M MAXWELL J P | 2008 | Consciousness and cogni- tion2008，17，： | 1 |
| 6 | Effects of lamb age,hormone stimulation and response to hormone stimulation on the yield and in vitro developmental competence of prepubertal lamb oocytes显示文摘 | Morton K M Catt S L Maxwell W M | | 0，，： | 1 |
| 7 | Sensitivity of condensation cured polysiloxane rubbers to sealed and open to air thermalageing regimes显示文摘 | Patel M Skinner A R Maxwell R S | 2005 | Polymer Testing2005，24，5： | 1 |
| 8 | Hyaluronan and hyaluronan synthases: potential therapeutic targets in cancer 显示文摘 | Adamia S Maxwell C A Pilarski L M | 2005 | Curt Drug Targets Cardiovasc Haematol Disord2005，5，1： | 1 |
| 9 | Expression of androgen and progesterone receptors in primary human meningiomas 显示文摘 | GALANOPOULUS T NEVILE G J | 1993 | J Neurosurg1993，78，3： | 1 |
| 10 | Effect of dietary man-nan oligosaccharides and(or)pharmacological additions of cop-per sulfate on growth performance and immunocompetence ofweanling and growing/finishing pigs显示文摘 | Davis M E Maxwell C V Brown D C | 2002 | J Anim Sci2002，80，11： | 1 |
| 11 | Myostatin negatively regulates satellite cell activation and self-renewal 显示文摘 | McCroskery S Thomas M Maxwell L | 2003 | J Cell Biol2003，162，6： | 1 |
| 12 | Species variation in the coronary collateral circulation during regional myocardial ischaemia:a infarction显示文摘 | Maxwell M P Hearse D J Yellon D M | | 0，，10： | 1 |
| 13 | The hypoxiaresponse pathway and p- cell function 显示文摘 | Cantley J Grey S T Maxwell P H M a/ | 2010 | DiabetesObes Metab2010，，2： | 1 |
| 14 | Passing Thoughts on the Evolutionary Stability of Implicit Motor Behaviour:Performance Retention Under Physiological Fatigue显示文摘 | Poolton J M Masters R S W Maxwell J P | 2007 | Consciousness and Cognition2007，16，2： | 1 |
| 15 | HGMS coal desulfurization with microwave magnetization enhancement 显示文摘 | Kelland D R Lai-Fook M Maxwell E | 1988 | IEEE Transactions on Magnetics1988，24，6： | 1 |
| 16 | The Arabidopsis histidine phosphotransfer proteins are redundant positive regulators of cytokinin signaling显示文摘 | Hutchison C.E Li J Argueso C Gonzalez M Lee E Lewis M.W Maxwell B.B Perdue T.D SchalLer G.E Alonso J.M Ecker J.R Kieber J.J | | 0，，： | 1 |
| 17 | Molecular characterization of the glycoproteins from two warm water rhabdoviruses:snakehead rhabdovirus(SHRV) and rhabdovirus of penaeid shrimp (RPS)/spring viremia of carp virus(SVCV)显示文摘 | Johnson M C Maxwell J M Loh P C | 1999 | Virus Research1999，64，2： | 1 |
| 18 | Membraue status of boar spermatozoa after cooling or ryopreservation 显示文摘 | Maxwell W M Johnson L A | 1997 | Theriogenology1997，48，2： | 1 |
| 19 | Fluorescent copper(I)complexes:an X-ray diffraction study of complexes of copper(I)iodide and pyridine derivatives of rhombic, ,and polymeric structure, and 显示文摘 | Rath N P Maxwell J L Holt E M | 1986 | J Chem Soc Dalt-on Trans1986，11，： | 1 |
| 20 | RhoC promotes human melanoma invasion in a PI3K/Akt-dependent pathway显示文摘 | Ruth M C Xu Y Maxwell I H | 2006 | J Invest Dermatol2006，126，4： | 1 |
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