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1篇 您的检索式：作者名="Matías M.Falco"

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		题名	作者	年代	出处	被引量
	1	Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection显示文摘Dear Editor,Drug repurposing is a convenient alternative when the need for new drugs in an unexpected medical scenario is urgent,as is the case of emerging pathogens.In recent years,approaches based on network biology have demonstrated to be superior to genecentric ones.1 Here,we use an innovative methodology that combines mechanistic modeling of the signal transduction circuits related to SARS-CoV-2 infection(the COVID-19 disease map)with a machine-learning algorithm that learns potential causal interactions between proteins,already targets of drugs,and specific signaling circuits in the COVID-19 disease map,to suggest potentially repurposable drugs.	Carlos Loucera Marina Esteban-Medina Kinza Rian Matías M.Falco Joaquín Dopazo María Peña-Chilet	2020	Signal Transduction and Targeted Therapy2020，5，1：	1

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