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35篇 您的检索式:作者名="Mary PL"
    题名 作者 年代 出处 被引量
1miR-200 family expression is downregulated upon neoplastic progression of Barrett's esophagus显示文摘AIM: To investigate miR-200 family expression in Barrett's epithelium, gastric and duodenal epithelia, and esophageal adenocarcinoma. METHODS: Real-time reverse transcriptase-polymerase chain reaction was used to measure miR-200, ZEB1 and ZEB2 expression. Ingenuity Pathway Analysis of miR-200 targets was used to predict biological outcomes. RESULTS: Barrett's epithelium expressed lower levels of miR-141 and miR-200c than did gastric and duodenal epithelia (P < 0.001). In silico analysis indicated roles for the miR-200 family in molecular pathways that distinguish Barrett's epithelium from gastric and duodenalepithelia, and which control apoptosis and proliferation. All miR-200 members were downregulated in adenocarcinoma (P < 0.02), and miR-200c expression was also downregulated in non-invasive epithelium adjacent to adenocarcinoma (P < 0.02). The expression of all miR-200 members was lower in Barrett's epithelium derived high-grade dysplastic cell lines than in a cell line derived from benign Barrett's epithelium. We observed signif icant inverse correlations between miR-200 family expression and ZEB1 and ZEB2 expression in Barrett's epithelium and esophageal adenocarcinoma (P < 0.05). CONCLUSION: miR-200 expression might contribute to the anti-apoptotic and proliferative phenotype of Barrett's epithelium and regulate key neoplastic processes in this epithelium.Cameron M Smith David I Watson Mary P Leong George C Mayne Michael Z Michael Bas PL Wijnhoven Damian J Hussey 2011World Journal of Gastroenterology2011,17,8:13
2Chemotherapy versus support cancer treatment in advanced gastric cancer:a meta-analysis显示文摘Casaretto L Sousa PL Mari JJ 0,,04:1
3Chemotherapy versus support cancer treatment in advanced gastric cancer:a meta-analysis显示文摘Casaretto L Sousa PL Mari JJ 2006Braz J Med and Biol Res2006,39,4:1
4Haemostatic and inflammatory biomaker in advanced chronic heart failure:role of oral anticoagulants and sucessful heart transplantation显示文摘Cugno M Mari D Meroni PL 2004Br J Haematol2004,126,1:1
5Haemostatic and inflammatory biomarker in advanced chronic heart failure: Role of oral anticoagulants and successful heart transplantation 显示文摘Cugno M Mari D Meroni PL 2004Br J Haematol2004,126,:1
6Deep arteriovenous malformations of the basal ganglia and thalamus:natural history显示文摘Ian GF Mary LM Richard PL 2003J Neurosurg2003,98,4:1
7Bone morphogenetic protein-2 and transforming growth factor-beta2 interact to human bone marrow stromal cell proliferation and differentiation显示文摘Fromigue O Marie PL Lomri A 1998J Cell Biochem1998,68,4:1
8Haemostatic and inflammatory biomarkers in advanced chronic heart failure:role of oral anticoagulants and successful heart transplantation显示文摘Cugno M Mari D Meroni PL 2004Br J Haematol2004,126,1:1
9Chemotherapy versus support cancer treatment in advanced gastric cancer:a meta-analysis显示文摘Casaretto L Sousa PL Mari JJ 2006Braz J Med Biol Res2006,39,4:1
10Haemostaticand inflam-matorybiomarker in advanced chronic heart failure:role of oral anticoagulants and successful heart transplantation显示文摘Cugno M Mari D Meroni PL 2004Br J Haematol2004,126,1:1
11Haemostatic and inflammatory biomarker in advanced chronic heart failure: role of oral anticoagulants and suecessful heart transplantation 显示文摘Cugno M Mari D Meroni PL 2004Br J Haematol2004,126,1:1
12Haemostatic and inflammatory biornarkers in advanced chronic heart failure:Role of oral anticoagulants and successful heart transplantation显示文摘Cugno M Mari D Meroni PL 2004Br J Haematol2004,126,1:1
13Haemostatic and inflammatory biomarkers in advanced chronic heart failure:role of oral anticoagulants and successful heart transplantation显示文摘 MARI D MERONI PL 2004Br J Heamatol2004,126,:1
14Haemostatic and inflammatory biomarkers in advanced chronic heart failure:role of oral anticoagulants and successful heart transplantation显示文摘Cugno M Mari D Meroni PL 2004Br J Haematol2004,126,1:1
15Chemotherapy versus support cancer treatment in advanced gastric cancer:a meta-analysis显示文摘Casaretto L Sousa PL Mari JJ 2006Braz J Med Biol Res2006,39,4:1
16Haemostatic and inflammatory biomarkers in advanced chronic heart failure: role of oral anticoagulants and successful heart transplantation显示文摘Cugno M Mari D Meroni PL 2004Br J Haematol2004,126,1:1
17Haemostatic and inflammatory biomarkers in advanced chronic heart failure:role of oral anticoagulants and successful heart transplantation显示文摘Cugno M Mari D Meroni PL 2004Br J Haematol2004,126,1:1
18Chemotherapy versus support cancer treatment in advanced gastric cancer:a meta-analysis显示文摘Casaretto L Sousa PL Mari JJ 2006Braz J Med Biol Res2006,39,4:1
19Chemotherapy versus support cancer treatment in advanced gastric cancer:a meta-analysis显示文摘Casaretto L Sousa PL Mari JJ 2006Braz J Med Biol Res2006,39,4:1
20Haemostatic and in-flammatory biomarkers in advanced chronic heartfailure: role of oral anticoagulants and successfulheart transplantation显示文摘Cugno M Mari D Meroni PL 2004Br J Haematol2004,126,1:1
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