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| 1 | Evidence that chronic hypoxia causes reversible impairment on male fertility显示文摘瞄准:在人的精子发生的参数和他们的复原时间上评估长期的组织缺氧的效果。方法:六男健康的山缓慢艰辛地旅行 ers 的 Seminological 参数在海水平在 normoxia 被评估。在到高度的 26 天暴露以后(从 2 000 m 到 5 600 m,古代蒙古帝国旧都遗迹远征) 一样的参数再在回到海水平以后被评估。这些参数再次在 6 个月以后在 1 个月以后然后再被评估。结果:精子计数被发现在回到海水平以后立即更低(P = 0.0004 ) 并且再在一个月以后(P = 0.0008 ) 。正常层次在 6 个月以后被到达。精子的活动性(%) 不在回到海水平以后立即显示出减小(P = 0.0583 ) ,而在 1 个月以后这减小是重要的(P = 0.0066 ) 。在 6 个月以后,到 pre-hypoxic 暴露值有恢复。在回到海以后立即增加的反常或不成熟的精子(%) 铺平(P = 0.0067 ) 然后再在 1 个月以后(P = 0.0004 ) 。在 6 个月以后,到起始的值有完全的恢复。在精液的能动精子的全部的数字被发现在回到海水平以后立即更低(P = 0.0024 ) 然后再在 1 个月以后(P = 0.0021 ) 。在 6 个月以后,到 pre-hypoxic 暴露值有恢复。结论:在 6 个月在精子发生和男富饶的生理的机制显示氧供应的影响以后,长期的组织缺氧在以前的 normoxic 条件的恢复导致精子减少的一个状态和如此的 seminological 参数的正规化。 | Vittore Verratti Francesco Berardinelli Camillo Di Giulio Gerardo Bosco Marisa Cacchio Mario Pellicciotta Michele Nicolai Stefano Martinotti Raffaele Tenaglia | 2008 | Asian Journal of Andrology2008，10，4： | 21 |
| 2 | Non-variceal upper gastrointestinal bleeding: Rescue treatment with a modified cyanoacrylate显示文摘AIM To evaluate the safety and efficacy of a modified cyanoacrylate [N-butyl-2-cyanoacrylate associated with methacryloxysulfolane(NBCA + MS)] to treat nonvariceal upper gastrointestinal bleeding(NV-UGIB).METHODS In our retrospective study we took into account 579 out of 1177 patients receiving endoscopic treatment for NV-UGIB admitted to our institution from 2008 to 2015; the remaining 598 patients were treated with other treatments. Initial hemostasis was not achieved in 45 of 579 patients; early rebleeding occurred in 12 of 579 patients. Thirty-three patients were treated with modified cyanoacrylate: 27 patients had duodenal, gastric or anastomotic ulcers, 3 had post-mucosectomy bleeding, 2 had Dieulafoy's lesions, and 1 had duodenal diverticular bleeding.RESULTS Of the 45 patients treated endoscopically without initialhemostasis or with early rebleeding, 33(76.7%) were treated with modified cyanoacrylate glue, 16(37.2%) underwent surgery, and 3(7.0%) were treated with selective transarterial embolization. The mean age of patients treated with NBCA + MS(23 males and 10 females) was 74.5 years. Modified cyanoacrylate was used in 24 patients during the first endoscopy and in 9 patients experiencing rebleeding. Overall, hemostasis was achieved in 26 of 33 patients(78.8%): 19 out of 24(79.2%) during the first endoscopy and in 7 out of 9(77.8%) among early rebleeders. Two patients(22.2%) not responding to cyanoacrylate treatment were treated with surgery or transarterial embolization. One patient had early rebleeding after treatment with cyanoacrylate. No late rebleeding during the follow-up or complications related to the glue injection were recorded.CONCLUSION Modified cyanoacrylate solved definitively NV-UGIB after failure of conventional treatment. Some reported life-threatening adverse events with other formulations, advise to use it as last option. | Roberto Grassia Pietro Capone Elena Iiritano Katerina Vjero Fabrizio Cereatti Mario Martinotti Gabriele Rozzi Federico Buffoli | 2016 | World Journal of Gastroenterology2016，22，48： | 8 |
| 3 | Angiotensin Ⅱ stimulates intercellularadhesion molecule-1 (ICAM-1) expression by human vascular endothelial cells and increasessoluble ICAM-1 release in vivo显示文摘 | Pastore L Tessitore A Martinotti S | 1999 | Circulation1999，100，： | 1 |
| 4 | Development of a new direct shear testing apparatus显示文摘 | BARLA G BARLA M MARTINOTTI M E | | 0，，01： | 1 |
| 5 | Efficacy and safety of fluoxetine monotherapy in bipolar depression: a systematic review显示文摘 | Martinotti G Sepede G Signorelli M | 2013 | Expert Opin Pharmacother2013，14，8： | 1 |
| 6 | Model simulation studies of complex free radical reactions:The graft copolymerization of styrene and acrylonitrile onto ethylene-propylene-isopropylidendicyclopentadiene terpolymer 显示文摘 | A Faucitano H Atarot F Faucitano Martinotti | 1980 | Journal of Polymer Science: Polymer Chemistry Edition1980，18，7： | 1 |
| 7 | Geochemistry, geochronology and petrology of Monte Mucrone: An example of Eo-alpine eclogitization of Permian granitoids in the Sesia-Lanzo zone, western Alps, Italy显示文摘 | Hunziker J C Martinotti G,Stern W B | 1985 | Chemical Geology1985，52，： | 1 |
| 8 | Angiotensin Ⅱ stimulates intercellular adhesion molecule-1 (ICAM-1) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo显示文摘 | Pastore L Tessitore A Martinotti S | 1999 | Circulation1999，100，15： | 1 |
| 9 | Psy- chometric characteristic of the Italian version of the Temperament and Character Inventory-Revised, personality, psychopathology, and at- tachment styles显示文摘 | Giovanni Martinotti Laura MandeUib G Robert Cloninger | 2008 | Comprehensive Psychiatry2008，49，： | 1 |
| 10 | Brain-derived neurotrophic factor and electroconvulsive therapy in a schizophrenic patient with treatment-resistant paranoid-hallucinatory symptoms显示文摘 | Martinotti G Ricci V Di Nicola M | 2011 | J ECT2011，27，1： | 1 |
| 11 | Angiotennin Ⅱ stimulates intercellular adhesion molecule-1 (ICAM-1) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo显示文摘 | Pastore L Tessitore A Martinotti S | 1999 | Circulation1999，100，15： | 1 |
| 12 | Angiotensin Ⅱ stimulates intercellular adhesion molecule-1 (ICAM-1) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo显示文摘 | Tessitore A Martinotti S | 1999 | Circulation1999，100，： | 1 |
| 13 | Cloning and characterization of different human sequences related to the onc gene (v-Myc) of avian myelocytomatosis virus (MC29)显示文摘 | Dalla-Favera R Gelmann E Martinotti S | 1982 | PNAS1982，79，21： | 1 |
| 14 | Nerve growth factor and brain-derived neurotrophic factor concentrations in schizophrenia:a review显示文摘 | MARTINOTTI G DI IORIO G MARINI S | 2012 | J Biol Regul Homeost Agents2012，26，3： | 1 |
| 15 | Angiotensin Ⅱ stimulates intercellular adhesion molecule-1 ( ICAM-1 ) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo 显示文摘 | Pastore L Tessitore A Martinotti S | 1999 | Circulation1999，100，15： | 1 |
| 16 | Angiotensin Ⅱ stimulates intercellular adhesion molecule-1 (ICAM-1) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo显示文摘 | L Pastore A Tessitore S Martinotti | 1999 | Circulation1999，100，： | 1 |
| 17 | Psy- chometric characteristic of the Italian version of the Temperament and Character Inventory-Revised, personality, psychopathology, and at- tachment styles 显示文摘 | Giovanni Martinotti Laura Mandellib C Robert Cloninger | 2008 | Comprehensive Psychiatry2008，49，： | 1 |
| 18 | Angiotensin Ⅱ stimulates intercellular adhesion molecule-1(ICAM-1) expression by human vascular endothelial cells and increases soluble ICAM-1 release in vivo显示文摘 | Pastore L Tessitore A Martinotti S | 1999 | Circulation1999，100，： | 1 |
| 19 | Nerve growth factor and brain-derived neurophic factor concentrations in schizophrenia= a review显示文摘 | Martinotti G Dilorio G Marini S etal | 2012 | J Biol Requl Homeost Agents2012，26，3： | 1 |
| 20 | A poly- morphism in the cyclooxygenase 2 gene as an inheri- ted protective factor against myocardial infarction and stroke显示文摘 | Cipollone F Toniato E Martinotti S | 2004 | JAMA2004，291，18： | 1 |
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