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| 1 | ABCD^(2) risk score does not predict the presence of cerebral microemboli in patients with hyper-acute symptomatic critical carotid artery stenosis显示文摘Introduction:ABCD^(2) risk score and cerebral microemboli detected by transcranial Doppler(TCD)have been separately shown to the predict risk of recurrent acute stroke.We studied whether ABCD2 risk score predicts cerebral microemboli in patients with hyper-acute symptomatic carotid artery stenosis.Participants and methods:We studied 206 patients presenting within 2 weeks of transient ischaemic attack or minor stroke and found to have critical carotid artery stenosis(≥50% ).86 patients(age 70±1(SEM:years),58 men,83 Caucasian)had evidence of microemboli;72(84% )of these underwent carotid endarterectomy(CEA).120 patients(age 72±1 years,91 men,113 Caucasian)did not have microemboli detected;102(85% )of these underwent CEA.Data were analysed using X2 and Mann–Whitney U tests and receiver operating characteristic(ROC)curves.Results:140/206(68% :95% CI 61.63 to 74.37)patients with hyper-acute symptomatic critical carotid stenosis had an ABCD2 risk score≥4.There was no significant difference in the NICE red flag criterion for early assessment(ABCD^(2) risk score≥4)for patients with cerebral microemboli versus those without microemboli(59/86 vs 81/120 patients:OR 1.05 ABCD2 risk score≥4(95% CI 0.58 to 1.90,p=0.867)).The ABCD2 risk score was<4 in 27 of 86(31% :95% CI 21 to 41)embolising patients and in 39 of 120(31% :95% CI 23 to 39)without cerebral microemboli.After adjusting for pre-neurological event antiplatelet treatment(APT),area under the curve(AUC)of ROC for ABCD2 risk score showed no prediction of cerebral microemboli(no pre-event APT,n=57:AUC 0.45(95% CI 0.29 to 0.60,p=0.531);preevent APT,n=147:AUC 0.51(95% CI 0.42 to 0.60,p=0.804)).Conclusions:The ABCD2 score did not predict the presence of cerebral microemboli or carotid disease in over one-quarter of patients with symptomatic critical carotid artery stenosis.On the basis of NICE guidelines(refer early if ABCD2≥4),assessment of high stroke risk based on ABCD2 scoring may lead to inappropriate delay in urgent treatment in many patients. | Mahmud Saedon Charles E Hutchinson Christopher H E Imray Donald R J Singer | 2017 | Stroke & Vascular Neurology2017，2，2： | 6 |
| 2 | Numerical Simulation of Turbulent Batch Mixing in a Vessel Agi-tated by A Rushton Turbine显示文摘 | Jaced K H Mahmud T Zhu J M | | 0，，02： | 1 |
| 3 | Human papillomavirus infections with multiple types and risk of cervical neoplasia显示文摘 | Trottier H Mahmud S Costa MC | 2006 | Cancer Epidemiol Biomarkers Prev2006，15，7： | 1 |
| 4 | Brinkman Forchheimer mod -eling for porous media thermoacoustie system 显示文摘 | Tasnim S H Mahmud S Fraser R A | 2011 | International Journal of Heat and Mass Transfer2011，54，1718： | 1 |
| 5 | Biosyn thesis of the validamycins :identification of intermediates in the biosyn thesis of validamycin a by streptomyces hygro scopicus var limoneus显示文摘 | DONG H J MAHMUD T TORNUS I | 2001 | J Am Chem Soc2001，123，： | 1 |
| 6 | Human papillomavirus infections with multiple types and risk of cervical neoplasia 显示文摘 | Trottier H Mahmud S Costa MC Sobfinho JP Duarte - Franco E Rohan TE | 2006 | Cancer Epidemiol Biomarkers Prey2006，15，： | 1 |
| 7 | The biosynthesis of acarbose and validamycin 显示文摘 | MAHMUD T LEE S FLOSS H G | | The Chemical Record0，，： | 1 |
| 8 | Miti- gation of soil erosion with jute geotextile aided by vegeta- tion cover: Optimization of an integrated tactic for sus- tainable soil conservation system (SSCS) 显示文摘 | Mahmud M M Chowdhury N H Elahi M M | 2012 | Global Journal of Researches in Engineering Civil and Structural Engineering2012，12，2： | 1 |
| 9 | Type-specific du- ration of human papillomavirus infection : implications for human papillomavirus screening and vaccination 显示文摘 | Trottier H Mahmud S Prado JC | 2008 | J Infect Dis2008，197，10： | 1 |
| 10 | Robust partial feedback linearizing stabilization scheme for three-phase grid-connected photovoltaic systems显示文摘 | Mahmud M A Pota H R Hossain M J | 2014 | IEEE Journal of Photovoltaics2014，4，1： | 1 |
| 11 | HLA polymor- phisms and cervical human papillomavirus infection in a cohort of montreal university students 显示文摘 | Mahmud SM Robinson K Richardson H | 2007 | J Infect Dis2007，196，： | 1 |
| 12 | Occurrence, seasonality and genetic diversity of Vibrio vulnifwus in coastal sea- weeds and water along the Kii Channel, Japan 显示文摘 | MAHMUD Z H NEOGI S B KASSU A | 2008 | Ferns Micro- Biol Ecol2008，64，2： | 1 |
| 13 | Differential importance of trehalose accumulation in Saccharomyces cerevisiae in response to various environmental stresses显示文摘 | Mahmud SA Hirasawa T Shimizu H | 2010 | Journal of Bioscience and Bioengineering2010，109，3： | 1 |
| 14 | Numerical simulation of turbulent batch mixing in a vessel agitated by a Rushton turbine 显示文摘 | JAVED K H MAHMUD T ZHU J M | 2006 | Chemical Engineering and Processing2006，45，： | 1 |
| 15 | Human papillomavirus infections with multiple types and risk of cervical neoplasia显示文摘 | Trottier H Mahmud S Costa MC | 2006 | Cancer Epidemiol Biomarkers Prey2006，15，： | 1 |
| 16 | HLA polymorphisms and cervical human papillomavirus Infection in a cohort of Montreal University students 显示文摘 | Mahmud SM Robinson K Richardson H | 2007 | J Infect Dis2007，196，1： | 1 |
| 17 | The significance oI cystic duct stones encountered during laparoscopic cholecystectomy 显示文摘 | Mahmud S H amza Y Nas sar HM | 2001 | Surg Endosc2001，15，5： | 1 |
| 18 | Effect of surface waviness and aspect ratio on heat transfer inside a wavy enclosure显示文摘 | Das P K Mahmud S Tasnim S H | 2003 | International Journal for Numerical Methods in Heat & Fluid Flow2003，13，8： | 1 |
| 19 | Structural, electrical transport, and magrietic properties of Ni1-x ZnxFe2O4 显示文摘 | Akther Hossain A K M Mahmud S T Sekim Kawai T Tabata H | 2007 | J Magn Magn Mater2007，312，： | 1 |
| 20 | Conjugation of Arginine-Glycine-Aspartic acid peptides to poly(ethylene oxide)-b-poly(-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells显示文摘 | XIONG XB MAHMUD A ULUDA H | 2006 | Biomacromolecules2006，8，3： | 1 |
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