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| 1 | The interaction among gut microbes,the intestinal barrier and short chain fatty acids显示文摘The mammalian gut is inhabited by a massive and complicated microbial community, in which the hostachieves a stable symbiotic environment through the interdependence, coordination, reciprocal constraintsand participation in an immune response. The interaction between the host gut and themicrobiota is essential for maintaining and achieving the homeostasis of the organism. Consequently, guthomeostasis is pivotal in safeguarding the growth and development and potential productive performanceof the host. As metabolites of microorganisms, short chain fatty acids are not only the preferredenergy metabolic feedstock for host intestinal epithelial cells, but also exert vital effects on antioxidantsand the regulation of intestinal community homeostasis. Herein, we summarize the effects of intestinalmicroorganisms on the host gut and the mechanisms of action of short chain fatty acids on the fourintestinal barriers of the organism, which will shed light on the manipulation of the intestinal communityto achieve precise nutrition for specific individuals and provide a novel perspective for theprevention and treatment of diseases. | Jiayu Ma Xiangshu Piao Shad Mahfuz Shenfei Long Jian Wang | 2022 | Animal Nutrition2022，，2： | 15 |
| 2 | Phenolic compounds as natural feed additives in poultry and swine diets:a review显示文摘Due to ban on using antibiotics in feed industry,awareness of using natural feed additives have led to a great demand.The interest of plants phenolic compounds as a potential natural antioxidant source has been considered in research community due to their predictable potential role as feed additives in poultry and swine production.However,the mode of action for their functional role and dosage recommendation in animal diets are still remain indistinct.Taking into account,the present review study highlights an outline about the mode of action of phenolic compound and their experimental uses in poultry and swine focusing on the growth performance,antioxidant function,immune function,antimicrobial role and overall health status,justified with the past findings till to date.Finally,the present review study concluded that supplementation of phenolic compounds as natural feed additives may have a role on the antioxidant,immunity,antimicrobial and overall production performance in poultry and swine. | Shad Mahfuz Qinghui Shang Xiangshu Piao | 2021 | Journal of Animal Science and Biotechnology2021，12，3： | 4 |
| 3 | Impact of sugar beet pulp and wheat bran on serum biochemical profile,inflammatory responses and gut microbiota in sows during late gestation and lactation显示文摘Background:Sows are frequently subjected to various stresses during late gestation and lactation,which trigger inflammatory response and metabolic disorders.Dietary fiber can influence animal health by modulating gut microbiota and their by-products,with the effects depending upon the source of the dietary fiber.This study aimed to evaluate the impacts of different fiber sources on body condition,serum biochemical parameters,inflammatory responses and fecal microbiota in sows from late gestation to lactation.Methods:Forty-five multiparous sows(Yorkshire×Landrace;3–6 parity)were assigned to 1 of 3 dietary treatments from d 85 of gestation to the end of lactation(d 21 post-farrowing):a control diet(CON,a corn-soybean meal diet),a sugar beet pulp diet(SBP,20%SBP during gestation and 10%SBP during lactation),and a wheat bran diet(WB,30%WB during gestation and 15%WB during lactation).Results:Compared with CON,supplementation of SBP decreased(P<0.05)lactation BW loss,reduced(P<0.05)serum concentration of total cholesterol,non-esterified fatty acids,interleukin-6 and tumor necrosis factor-α,and increased(P<0.05)fecal water content on d 110 of gestation and d 21 of lactation,while supplementation of WB reduced(P<0.05)serum concentration of total cholesterol on d 110 of gestation,increased(P<0.05)fecal water content and decreased(P<0.05)serum interleukin-6 concentration on d 110 of gestation and d 21 of lactation.In addition,sows fed SBP had lower(P<0.01)abundance of Clostridium_sensu_stricto_1 and Terrisporobacter than those fed CON,but had greater(P<0.05)abundance of Christensenellaceae_R-7_group and Ruminococcaceae_UCG-002 than those fed the other two diets on d 110 of gestation.On d 21 of lactation,supplementation of SBP decreased(P<0.05)the abundance of Firmicutes and Lactobacillus,but enriched(P<0.05)the abundance of Christensenellaceae_R-7_group,Prevotellaceae_NK3B31_group,Ruminococcaceae_UCG-002,Prevotellaceae_UCG_001 and unclassified_f__Lachnospiraceae compared with WB.Compared with CON,sows fed SBP had greater(P<0.05)fecal concentrations of acetate,butyrate and total SCFAs during gestation and lactation,while sows fed WB only had greater(P<0.05)fecal concentration of butyrate during lactation.Conclusions:Supplementation of dietary fiber during late gestation and lactation could improve sow metabolism and gut health,and SBP was more effective than WB. | Qinghui Shang Sujie Liu Hansuo Liu Shad Mahfuz Xiangshu Piao | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 4 |
| 4 | 小刺猴头菌发酵浸膏多糖体外抗氧化活性分析显示文摘为研究小刺猴头菌[Hericium caput-medusae(Bull.:Fr.)Pers]发酵浸膏多糖的抗氧化活性。以工厂化小刺猴头菌发酵浸膏为原料,采用透析法分级,DEAE sepharose fast flow柱层析纯化,分别获得粗多糖组分HFCP1和中性多糖HFCP1-1;通过PMP柱前衍生-高效液相色谱法和红外光谱法对单糖组成和结构进行分析,单糖组成均以葡萄糖和半乳糖为主。化学法检测多糖抗氧化活性,结果显示:HFCP1和HFCP1-1清除羟基自由基、超氧阴离子自由基、2,2′-联氮-二(3-乙基-苯并噻唑-6-磺酸)二铵盐(2,2′-azinobis-3-ethylbenzthiazoline-6-sulphonate,ABTS+)和1,1-二苯基-2-三硝基苯肼(1,1-diphenyl-2-picrylhydrazyl,DPPH)的IC50值分别为7.66和6.77mg/mL、6.16和5.30mg/mL、0.63和0.85mg/mL、0.39和2.62mg/mL。以RAW264.7细胞建立H2O2诱导损伤模型,细胞抗氧化结果表明:HFCP1和HFCP1-1处理组与模型组相比均显著增强细胞活力(P<0.05),浓度为100和200mg/L时MDA含量与模型组相比均显著下降(P<0.05);HFCP1浓度为100和200mg/L时与模型组相比显著增加SOD和GSH-Px的活性(P<0.05);HFCP1-1浓度为200mg/L时与模型组相比显著增加SOD活性(P<0.05);也能增加GSH-Px的活性,但未达到显著水平(P>0.05)。 | 任桂红 苗月 李肖宏 Mahfuz Shad 甄东 宋慧 | 2018 | 中国农业大学学报2018，23，12： | 4 |
| 5 | Comparison of antioxidant activity of clove ( Eugenia caryophylata Thunb) buds and lavender ( Lavandula stoechas L.)显示文摘 | ìlhami Gül?in ?. Güng?r ?at ?ükrü Beydemir Mahfuz Elmasta? ?. ?rfan Küfrevio?lu | 2004 | Food Chemistry2004，，3： | 3 |
| 6 | SOX2 in cancer stemness: tumor malignancy and therapeutic potentials显示文摘Cancer stem cells(CSCs),a minor subpopulation of tumor bulks with self-renewal and seeding capacity to generate new tumors,posit a significant challenge to develop effective and long-lasting anti-cancer therapies.The emergence of drug resistance appears upon failure of chemo-/radiation therapy to eradicate the CSCs,thereby leading to CSC-mediated clinical relapse.Accumulating evidence suggests that transcription factor SOX2,a master regulator of embryonic and induced pluripotent stem cells,drives cancer stemness,fuels tumor initiation,and contributes to tumor aggressiveness through major drug resistance mechanisms like epithelial-to-mesenchymal transition,ATP-binding cassette drug transporters,anti-apoptotic and/or pro-survival signaling,lineage plasticity,and evasion of immune surveillance.Gaining a better insight and comprehensive interrogation into the mechanistic basis of SOX2-mediated generation of CSCs and treatment failure might therefore lead to new therapeutic targets involving CSC-specific anti-cancer strategies. | Mahfuz Al Mamun Kaiissar Mannoor Jun Cao Firdausi Qadri Xiaoyuan Song | 2020 | Journal of Molecular Cell Biology2020，12，2： | 3 |
| 7 | Damage tolerance of resin infiltrated composites under low velocity impact-experimental and numerical studies 显示文摘 | Saha M Biggs R | 1998 | Key Engineering Materials1998，，： | 1 |
| 8 | Fracture and Flexural Characterization of SiCw/SiC Composites at Room and Elevated Temperatures 显示文摘 | Mahfuz H Zadoo DP Wilks F | 1995 | Journal of Mate- rials Science1995，30，： | 1 |
| 9 | A high-throughput DLMS adaptive algorithm显示文摘 | Ejaz Mahfuz Wang Chunyan Omair M | 2005 | IEEE Trans on Circuits and Systems2005，23，： | 1 |
| 10 | Fabrication, synthesis and mechanical characterization of nanoparticles infused polyurethane foams显示文摘 | Hassan Mahfuz Vijaya K Rangari Mohammed S Islam | 2004 | Composites: Part A2004，35，： | 1 |
| 11 | Effect of SiO2 nanoparticle on thermal and tensile behavior of nylon-6显示文摘 | Hasan M M Zhou Yuanxin Mahfuz H | 2006 | Materials Science and Engineering A2006，429，： | 1 |
| 12 | Radical scavenging and antioxidant activity of tannic acid显示文摘 | Ilhami Gulcin Zubeyr Huyut Mahfuz Elmastas | 2010 | Arabian Journal of Chemistry2010，3，1： | 1 |
| 13 | Effect of Density, Microstructure, and Strain Rate on Com- pression Behavior of Polymeric Foams 显示文摘 | SAHA M C MAHFUZ H CHAKRAVARTY U K | 2005 | Materials Sci- ence and Engineering A2005，406，12： | 1 |
| 14 | Fabrication,Synthesis and Mechanical Characterization of Nanoparticles Infused Polyurethane Foams显示文摘 | Mahfuz H Rangari V K Islam M S | 2004 | Composites Part A:Applied Science and Manufacturing2004，35，4： | 1 |
| 15 | Fracture and flexural characterization of SiCw/SiC composites at room and elevated temperatures 显示文摘 | MAHFUZ H ZADOO D P WILKS F | 1995 | J Mater Sci1995，30，： | 1 |
| 16 | Determination of antioxidant activity and antioxidant compounds in wild edible mushrooms 显示文摘 | Mahfuz E Omer I Ibrahim T | 2007 | Journal of Food Composition and Analysis2007，20，34： | 1 |
| 17 | Fracture and Flexural Characterization of SiCw/SiC Composites at Room and Elevated Temperatures显示文摘 | Mahfuz H Zadoo D P Wilks F | 1995 | Journal of Materials Science1995，30，： | 1 |
| 18 | Enzyme-assisted aqueous extraction of oil and protein from soybcans and cream de-emulsification显示文摘 | de Moura JMLN Campbell K Mahfuz A | 2008 | J Am Oil Chem Soc2008，85，10： | 1 |
| 19 | Enzyme - as- sisted aqueous extraction of oil and protein from soybeans and cream de - emulsification 显示文摘 | de Moura JMLN Campbell K Mahfuz A | 2008 | Journal of the American Oil Chemists'' Society2008，85，98： | 1 |
| 20 | Low temperature dry extrusion and high - pressure processing prior to enzyme - assisted aqueous extraction of full fat soybean flakes 显示文摘 | Stephanie Jung Abdullah A Mahfuz | 2008 | Food Chemistry2008，44，10： | 1 |
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