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| 1 | Coronary artery calcium score on low-dose computed tomography for lung cancer screening显示文摘AIM: To evaluate the feasibility of coronary artery calcium score(CACS) on low-dose non-gated chest CT(ngCCT).METHODS: Sixty consecutive individuals(30 males; 73 ± 7 years) scheduled for risk stratification by means of unenhanced ECG-triggered cardiac computed to-mography(gCCT) underwent additional unenhanced ngCCT. All CT scans were performed on a 64-slice CT scanner(Somatom Sensation 64 Cardiac, Siemens, Germany). CACS was calculated using conventional methods/scores(Volume, Mass, Agatston) as previ-ously described in literature. The CACS value obtained were compared. The Mayo Clinic classification was used to stratify cardiovascular risk based on Agatston CACS. Differences and correlations between the two methods were compared. A P-value < 0.05 was considered sig-nificant.RESULTS: Mean CACS values were significantly higher for gCCT as compared to ngCCT(Volume: 418 ± 747 vs 332 ± 597; Mass: 89 ± 151 vs 78 ± 141; Agatston: 481 ± 854 vs 428 ± 776; P < 0.05). The correlation between the two values was always very high(Volume: r = 0.95; Mass: r = 0.97; Agatston: r = 0.98). Of the 6 patients with 0 Agatston score on gCCT, 2(33%) showed an Agatston score > 0 in the ngCCT. Of the 3 patients with 1-10 Agatston score on gCCT, 1(33%) showed an Agatston score of 0 in the ngCCT. Overall, 23(38%) patients were reclassified in a different car-diovascular risk category, mostly(18/23; 78%) shifting to a lower risk in the ngCCT. The estimated radiation dose was significantly higher for gCCT(DLP 115.8 ± 50.7 vs 83.8 ± 16.3; Effective dose 1.6 ± 0.7 mSv vs 1.2 ± 0.2 mSv; P < 0.01).CONCLUSION: CACS assessment is feasible on ngCCT; the variability of CACS values and the associated re-stratification of patients in cardiovascular risk groups should be taken into account. | Teresa Arcadi Erica Maffei Nicola Sverzellati Cesare Mantini Andrea I Guaricci Carlo Tedeschi Chiara Martini Ludovico La Grutta Filippo Cademartiri | 2014 | World Journal of Radiology2014，6，6： | 4 |
| 2 | 在有症状的患者中,与传统危险因素相比,冠状动脉钙化积分能更准确地预测显著的冠状动脉狭窄:欧洲钙化性冠状动脉疾病研究显示文摘在这项回顾性研究中,研究人员评估了冠状动脉钙化积分相对于传统危险因素对显著狭窄(冠状动脉狭窄〉50%)的预测价值。方法与结果:纳入来自丹麦、法国、德国、意大利、西班牙和美国有症状的患者5515例,所有研究对象均进行危险因素评估、计算机断层冠状动脉造影(computed tomographic coronary angiogram,CTCA)或常规血管造影。 | 刘莉 叶鹏 Nicoll R Wiklund U Zhao Y Diederichsen A Mickley H Ovrehus K Zamorano P Gueret P Schmermund A Maffei E Cademartiri F Budoff M Henein M | 2016 | 中华高血压杂志2016，24，3： | 4 |
| 3 | 有 CT 冠的 angiography 的匾成像: 匾类型分类上的 intra 脉管的变细的效果显示文摘 AIM:To assess the attenuation of non-calcified atherosclerotic coronary artery plaques with computed tomography coronary angiography(CTCA).METHODS:Four hundred consecutive patients underwent CTCA(Group 1:200 patients,Sensation 64 Cardiac,Siemens;Group 2:200 patients,VCT GE Healthcare,with either Iomeprol 400 or Iodixanol 320,respectively) for suspected coronary artery disease(CAD).CTCA was performed using standard protocols.Image quality(score 0-3),plaque(within the accessible non-calcified component of each non-calcified/mixed plaque) and coronary lumen attenuation were measured.Data were compared on a per-segment/perplaque basis.Plaques were classified as fibrous vs lipid rich based on different attenuation thresholds.A P < 0.05 was considered significant.RESULTS:In 468 atherosclerotic plaques in Group 1 and 644 in Group 2,average image quality was 2.96 ± 0.19 in Group 1 and 2.93 ± 0.25 in Group 2(P ≥ 0.05).Coronary lumen attenuation was 367 ± 85 Hounsfield units(HU) in Group 1 and 327 ± 73 HU in Group 2(P < 0.05);non-calcified plaque attenuation was 48 ± 23 HU in Group 1 and 39 ± 21 HU in Group 2(P < 0.05).Overall signal to noise ratio was 15.6 ± 4.7 in Group 1 and 21.2 ± 7.7 in Group 2(P < 0.01).CONCLUSION:Higher intra-vascular attenuation modifies significantly the attenuation of non-calcified coronary plaques.This results in a more difficult characterization between lipid rich vs fibrous type. | Erica Maffei Chiara Martini Teresa Arcadi Alberto Clemente Sara Seitun Alessandra Zuccarelli Tito Torri Nico R Mollet Alexia Rossi Onofrio Catalano Giancarlo Messalli Filippo Cademartiri | 2012 | World Journal of Radiology2012，4，6： | 3 |
| 4 | Oxidative status and cardiovascular risk in women:Keeping pink at heart显示文摘Although cardiovascular disease(CVD) has always been perceived as a pathology regarding essentially males,incidence and death from cardiovascular events dramatically increase after menopause in women.Obviously,while many aspects of CVD are similar in both sexes,it is now clear that there are significant differences as well.Exploration of these gender-related differences in CVD might provide a basis for the development of new strategies in the management of patients with CVD from a gender point of view.In particular,a growing amount of data suggested the possible major role of oxidative stress in female patients and the possibility to integrate this new biomarker in future study evaluating CVD risk in women. | Cristina Vassalle Antonella Mercuri Silvia Maffei | 2009 | World Journal of Cardiology2009，1，1： | 3 |
| 5 | Positional cloning of the mouse obese gene and its human homologue显示文摘 | Zhang Y Proenca R Maffei M | | 0，，： | 3 |
| 6 | Weight-reducing effects of the plasma protein encoded by the obese gene显示文摘 | Halaas JL Gajiwala KS Maffei M | | 0，，： | 3 |
| 7 | Determination of selenium in Italian rices by differential pulse cathodic stripping voltammetry显示文摘 | Monica Panigati Luigi Falciola Patrizia Mussini Giangiacomo Beretta Roberto Maffei Facino | 2007 | Food Chemistry2007，，3： | 2 |
| 8 | Positional cloning of the mouse obsese gene and its human homologue显示文摘 | Zhang Y Proenca R Maffei M | 1994 | Nature1994，372，： | 1 |
| 9 | Positional cloning of the mouse obese gene and its human homologue 显示文摘 | Proenca R Maffei M | 1994 | Nature1994，372，： | 1 |
| 10 | Positional cloning of the mouse obese gene and its human homologue显示文摘 | Proenca R Maffei M | 1994 | Nature1994，，372： | 1 |
| 11 | Positional cloning of the mouse obses gene and its human homologue显示文摘 | Zhang Y Proenca R Maffei M | 1994 | Nature1994，372，： | 1 |
| 12 | Alstrom syndrome 显示文摘 | Marshall JD Beck S Maffei P | 2007 | EurJ Hum Genet2007，15，12： | 1 |
| 13 | ANGPT2 promoter methylation is strongly associated with gene expression and prognosis in chronic lymphocytic leukemia显示文摘 | Martinelli S Kanduri M Maffei R | 2013 | Epigenetics2013，8，7： | 1 |
| 14 | RF - plannarmagnetron sputtering and characterization of ferroeleetrie PZT films显示文摘 | Krupanidhi SB Maffei N Sayer M | 1983 | Appl Phys1983，54，： | 1 |
| 15 | Positional cloning of the mouse obese gene and its human homologe显示文摘 | Procnca R Maffei M | 1994 | Nature1994，372，6505： | 1 |
| 16 | Positional cloning of the mouse obese gene and its human homologue 显示文摘 | Proenca R Maffei M | 1994 | Nature1994，372，： | 1 |
| 17 | Plasticity in the visual system: role of neurotrophins and electrical activity 显示文摘 | Maffei L | 2002 | Arch Ital Biol2002，140，4： | 1 |
| 18 | Temperament,character,and attachment patterns in borderline personality disorder显示文摘 | Fossati A Donati D Donini M Novella L Bagnato M Maffei C | 2001 | J Personal Disord2001，15，： | 1 |
| 19 | Fat intake and adiposity in 8 to 11-year-old obese children显示文摘 | Maffeis C Pinelli L Schutz Y | 1996 | Int J Obes Relat Metab Disord1996，20，： | 1 |
| 20 | Positional cloning of the mouse obese gene and its human homologue 显示文摘 | Zhang Y Proenca R Maffei M | 1994 | Nature1994，372，6505： | 1 |
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