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| 1 | 高纤维膳食和补充乙酸盐改变肠道菌群,预防醋酸脱氧皮质酮-盐型高血压小鼠高血压和心力衰竭的发展显示文摘水果和蔬菜的膳食摄入与高血压的发生率较低有关,但所涉及的机制尚未阐明。该研究评估了高纤维膳食和短链脂肪酸(short-chain fatty acid,SCFA)(乙酸盐)对肠道微生物群和预防心血管病的影响。方法:用盐皮质激素诱发小鼠高血压模型,观测正常喂食组、高纤维喂食组和补充乙酸盐组的肠道微生物、心脏结构/功能和血压水平。 | 刘莉 叶鹏 Marques FZ Nelson EM Chu PY Horlock D Fiedler A Ziemann M Tan JK Kuruppu S Rajapakse NW El-Osta A Mackay CR Kaye DM | 2016 | 中华高血压杂志2016，24，12： | 8 |
| 2 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 3 | The role of chemokine receptors in primary effector and memory immune responses显示文摘 | Sallusto F Mackay C R Lanzavecchia A | | 0，，： | 3 |
| 4 | A missense mutation in the gamma D crystallin gene (CRYGD) associated with autosomal dominant ''coral-like'' cataract linked to chromosome 2q显示文摘 | Mackay DS Andley UP Shiels A | 2004 | Mol Vis2004，10，： | 2 |
| 5 | Reverse micellar synthesis of a nanoparticle/polymer composite 显示文摘 | Pavel F M Mackay R A | 2000 | Langmuir2000，16，23： | 1 |
| 6 | Modeling tetracycline antibiotic sorption to clays显示文摘 | Figueroa R A Leonard A MacKay A A | 2003 | Environmental Science & Technology2003，38，2： | 1 |
| 7 | Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated response显示文摘 | Sallusto F Lanzavecchia A Mackay CR | 1998 | Immunol Today1998，19，： | 1 |
| 8 | Multilineage paential of adult human mesenchymal stem cells 显示文摘 | PITFENGER M F MACKAY A M BECK S C | 1999 | Science1999，284，5411： | 1 |
| 9 | identification of the 72- kDa(MMP - 2)and 92 - kDa(MMP - 9)gelatinase type iv collar - genase in preparations of laminin and Matrigel 显示文摘 | Mackay A R Gomez D E Cottam D W | 1993 | Biotech - niques1993，15，： | 1 |
| 10 | Guideline to reference gene selection for quantitative real-time PCR显示文摘 | Radonic A Thulke S Mackay 1M | 2004 | Biochem Biophys Res Commun2004，313，4： | 1 |
| 11 | Real-time PCR in Virology 显示文摘 | Mackay I M Arden K E Nitsche A | 2002 | Nucleic Acids Res2002，30，6： | 1 |
| 12 | A Frame-work for classifying and quantifying the natural, capital, and e- cosystem services of soils显示文摘 | DOMINATI E PATTERSON M MACKAY A | 2010 | Ecological Economics2010，69，： | 1 |
| 13 | Multilineage potential of adult human mesenchymal stem cells显示文摘 | Pittenger M F Mackay A M Beck S C | | 0，，5411： | 1 |
| 14 | Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanoma显示文摘 | Pilon-Thomas S Mackay A Vohra N | 2010 | J Immunol2010，184，7： | 1 |
| 15 | Modeling tetracycline antibiotic sorotion to clays显示文摘 | Figueroa R A Leonard A MacKay A A | 2004 | Environ Sci Technol2004，38，2： | 1 |
| 16 | Chemokines and chemokine receptors in T-cell priming and TH1/TH2-mediated responses显示文摘 | Lanzavecchia A Mackay CR | 1998 | Immunol Today1998，19，12： | 1 |
| 17 | Guideline to reference gene selection for quantitative real-time PCR 显示文摘 | Radonic A Thulke S Mackay IM | 2004 | Siochem Siophys Res Commun2004，313，4： | 1 |
| 18 | The natural history of ankylosing spondylitis as defined by radiological progression 显示文摘 | Brophy S Mackay K A1 Saidi A | 2002 | J Rheumatol2002，29，： | 1 |
| 19 | Sorption of oxytetracycline to iron oxides and iron oxide-rich soils显示文摘 | Figueroa R A MacKay A A | 2005 | Environmental Science & Technology2005，39，17： | 1 |
| 20 | Real-time PCR in virology显示文摘 | Mackay IM Arden KE Nitsche A | 2002 | Nucleic Acids Res2002，30，6： | 1 |
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