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| 1 | Microfluidic actuators based on temperature-responsive hydrogels显示文摘The concept of using stimuli-responsive hydrogels to actuate fluids in microfluidic devices is particularly attractive,but limitations,in terms of spatial resolution,speed,reliability and integration,have hindered its development during the past two decades.By patterning and grafting poly(N-isopropylacrylamide)PNIPAM hydrogel films on plane substrates with a 2μm horizontal resolution and closing the system afterward,we have succeeded in unblocking bottlenecks that thermo-sensitive hydrogel technology has been challenged with until now.In this paper,we demonstrate,for the first time with this technology,devices with up to 7800 actuated micro-cages that sequester and release solutes,along with valves actuated individually with closing and opening switching times of 0.6±0.1 and 0.25±0.15 s,respectively.Two applications of this technology are illustrated in the domain of single cell handling and the nuclear acid amplification test(NAAT)for the Human Synaptojanin 1 gene,which is suspected to be involved in several neurodegenerative diseases such as Parkinson’s disease.The performance of the temperature-responsive hydrogels we demonstrate here suggests that in association with their moderate costs,hydrogels may represent an alternative to the actuation or handling techniques currently used in microfluidics,that are,pressure actuated polydimethylsiloxane(PDMS)valves and droplets. | Loïc D'Eramo Benjamin Chollet Marie Leman Ekkachai Martwong Mengxing Li Hubert Geisler Jules Dupire Margaux Kerdraon Clémence Vergne Fabrice Monti Yvette Tran Patrick Tabeling | 2018 | Microsystems & Nanoengineering2018，4，1： | 3 |
| 2 | Instantaneous Parameter Estimation in cardiovascular time-frequency analysis 显示文摘 | Monti A Medigue C Mangin L | 2002 | IEEE Transactions on Biomedical Engineering2002，49，12： | 1 |
| 3 | Association of insulin resistance, hyperleptinemia, and impaired nitric oxide release with in-stent restenosis in patients undergoing coronary stenting显示文摘 | Piatti P Di Mario C Monti LD | 2003 | Circulation2003，108，17： | 1 |
| 4 | Efficacy of donkey' s milk in treating highly problematic cow' s milk allergic children:an in vivo and in vitro study显示文摘 | Monti G Bertino E Muratore M C | 2007 | Pediatric Allergy and Immunology2007，18，： | 1 |
| 5 | SAR Interferometry: A “quiek and dirty” coherence estimator for data browsing显示文摘 | Monti Guarnieri A Prati C | 1997 | IEEE Transactions on Geoscience and Remote Sensing1997，35，3： | 1 |
| 6 | Xylanases from fungi:properties and industrial applications 显示文摘 | Polizeli M L T M Rizzatti A C S Monti R | 2005 | Appl Microbiol Biotechnol2005，67，： | 1 |
| 7 | Passive geosynchronous SAR system reusing backscattered digital audio broadcasting signals显示文摘 | C Prati F Rocca D Giancola A Monti Guamieri | 1998 | IEEE Transactions on Geoscience and Remote Sensing1998，36，6： | 1 |
| 8 | Xylanase from fungi : properties and industrial applications 显示文摘 | Polizeli M L T Rizzatti A C S Monti R | 2005 | Appl Mierohiol Biotechnol2005，67，5： | 1 |
| 9 | An overview of research using the one atmosphere uniform glow discharge plasma (OAU GDP) for sterilization of surfaces and materials 显示文摘 | Montie T C Kelly-Wintenberg K Roth J R | 2000 | IEEE Transactions on Plasma Science2000，28，1： | 1 |
| 10 | Crucial role of D1 dopamine receptors in mediating the antidepressant effect of imi- pramine显示文摘 | Gambarana C Ghiglieri O Tagliamonte A D Ales- sandro N de Montis M G | 1995 | Pharmacol Biochem Behav1995，50，： | 1 |
| 11 | Difficulties in maintaining long-term partial nitritation of ch sludge digester liquids in a moving-bed biofilm reactor (MBBR) 显示文摘 | Fux C Huang D Monti A | 2004 | Water Science and Technology2004，49，1112： | 1 |
| 12 | Intramyocardial hemorrhage: an enigma for cardiac MRI? 显示文摘 | Calvieri C Masselli G Monti R | 2015 | Biomed Res Int2015，2015，85： | 1 |
| 13 | The effects of exchange bias on Fe-Co/MgO magnetic nanoparticles with core/shell morphology显示文摘 | Martinez-Boubeta C BalceUsl L Monty C | 2010 | Journal of Physics: Condensed Matter2010，22，2： | 1 |
| 14 | Synthesis of Al-doped ZnO nanomaterials with controlled luminescence 显示文摘 | PITICESCU R R PITICESCU R M MONTY C J | 2006 | J Eur Ceram Soc2006，26，14： | 1 |
| 15 | Difficulties in maintaining long - term partial nitritation of ammonium - rich sludge digester liquids in a moving - bed biofilm reactor (MBBR) 显示文摘 | Fux C Huang D Monti A | 2004 | Water Science and Technology2004，49，1112： | 1 |
| 16 | Hydrothermal synthesis of zirconia nanomaterials显示文摘 | Piticescu R R Monty C Taloi D | 2001 | Journal of the European Ceramic Society2001，21，： | 1 |
| 17 | Subchronic rolipram delivery activates hippocampal CREB and arc, enhances retention and slows down extinction of conditioned fear显示文摘 | Monti B Berteotti C Contestabile A | 2006 | Neuropsychopharmacol:Offic Public Am Coll Neuropsychopharmacol2006，31，2： | 1 |
| 18 | Apoptosis, DNA damage and ubiquitin expression in normal and mdx muscle fibers after exercise显示文摘 | Sandri M Carraro U Podhorska-Okolov M Rizzi C Arslan P Monti D Franceschi C | 1995 | FEBS Lett1995，373，3： | 1 |
| 19 | 显示文摘 | Gadri Ben Rami Roth Reece J Montie C Thomas | 2000 | Surface and Coatings Technology2000，131，： | 1 |
| 20 | An overview of research using the one atmosphere uniform glow discharge plasma (OAUGDP) for sterilisation of surfaces and materials 显示文摘 | Montie T C Kelly Wintenberg K Roth J R | 2000 | IEEE Trans on Plasma Sci2000，28，1： | 1 |
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