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| 1 | Outcomes of liver transplantation in patients with hepatorenal syndrome显示文摘Hepatorenal syndrome(HRS) plays an important role in patients with liver cirrhosis on the wait list for liver transplantation(LT). The 1 and 5-year probability of developing HRS in cirrhotic with ascites is 20% and 40%, respectively. In this article, we reviewed current concepts in HRS pathophysiology, guidelines for HRS diagnosis, effective treatment options presently available, and controversies surrounding liver alone vs simultaneous liver kidney transplant(SLKT) in transplant candidates. Many treatment options including albumin, vasoconstrictors, renal replacement therapy, and eventual LT have remained a mainstay in the treatment of HRS. Unfortunately, even after aggressive measures such as terlipressin use, the rate of recovery is less than 50% of patients. Moreover, current SLKT guidelines include:(1) estimation of glomerular filtration rate of 30 m L/min or less for 4-8 wk;(2) proteinuria > 2 g/d; or(3) biopsy proven interstitial fibrosis or glomerulosclerosis. Even with these updated criteria there is a lack of consistency regarding longterm benefits for SLKT vs LT alone. Finally, in regards to kidney dysfunction in the post-transplant setting, an estimation of glomerular filtration rate < 60 mL /min per 1.73 m2 may be associated with an increased risk of patients having long-term end stage renal disease. HRS is common in patients with cirrhosis and those on liver transplant waitlist. Prompt identification and therapy initiation in transplant candidates with HRS may improve post-transplantation outcomes. Future studies identifying optimal vasoconstrictor regimens, alternative therapies, and factors predictive of response to therapy are needed. The appropriate use of SLKT in patients with HRS remains controversial and requires further evidence by the transplant community. | Rohan M Modi Nishi Patel Sherif N Metwally Khalid Mumtaz | 2016 | World Journal of Hepatology2016，8，24： | 8 |
| 2 | Serum retinol bindingprotein 4 contributes to insulin resistance in obesity and type 2diabetes显示文摘 | YANG Q GRAHAM TE MODY N | 2005 | Nature2005，436，7049： | 1 |
| 3 | Incidence and risk factors for development of venous thromboembolism in Indian patients undergoing major orthopaedic surgery:results of a prospective study显示文摘 | Bagaria V Modi N Panghate A | 2006 | Postgrad Med J2006，82，964： | 1 |
| 4 | Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes 显示文摘 | Yang Q Graham TE Mody N | 2005 | Nature2005，436，： | 1 |
| 5 | Serum retinol bindingprotein 4 contributes to insulin resistance in obesity and type 2diabetes显示文摘 | Yang Q Graham TE Mody N | 2005 | Nature2005，436，35： | 1 |
| 6 | Rosiglitazone sensitizes MDA-MB-231 breast cancer ceils to anti-tumour effects of turnout necrosis factor-alpha, CHll and CYC202显示文摘 | Mody M Dharker N Bloomston M | 2007 | Endocr Relat Cancer2007，14，2： | 1 |
| 7 | Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B显示文摘 | Delibegovic M Bence K K Mody N | 2007 | Mol Cell Biol2007，27，21： | 1 |
| 8 | Miniaturized gas ionization sensors using carbon nanotubes显示文摘 | Modi A Koratkar N Lass E | 2003 | Nature2003，424，： | 1 |
| 9 | Dendritc cell - based vaccine research against cancer 显示文摘 | Mody N Dubey S Sharma R | 2015 | Exper Rev Clin Immunol2015，11，2： | 1 |
| 10 | Percutaneous endoscopic lumbar herniectomy for high-grade down-migrated L4-L5 disc through an Ls-S1 interlaminar approach: a technical note 显示文摘 | Choi G Prada N Modi HN | 2010 | Minim Invas Neurosurg2010，53，3： | 1 |
| 11 | Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes显示文摘 | Yang Q Graham TE Mody N | 2005 | Nature2005，436，7049： | 1 |
| 12 | The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance显示文摘 | Yan QW Yang Q Mody N | | 0，，： | 1 |
| 13 | Assessment of lexical semantic judgment abilities in alcohol-dependent subjects: an fMRI study显示文摘 | Bagga D Singh N Modi S | 2013 | J Biosci2013，38，5： | 1 |
| 14 | Single-andmultipledose pharmacokinetics of an oralonce-a-dayosmotic controlled release ROS methy lphenidate HC1 fornmlation 显示文摘 | MODI N B LINDEMULDER B OUPTA S K | 2000 | Clin Pharmocol2000，40，4： | 1 |
| 15 | Miniaturized gas ionization sensors using carbon nanotubes 显示文摘 | Modi A Koratkar N Lass E | 2003 | Nature2003，424，： | 1 |
| 16 | Structure revision of 37 lycoctonine-related diterpenoid alkaloids 显示文摘 | Pelletier S W Mody N V Varughase K I | 1981 | J Am Chera Soc1981，103，： | 1 |
| 17 | Role of the cholesterol biosynthetic pathway in osteoblastic differentiation of marrow stromal cells显示文摘 | Parhami F Mody N Gharavi N | 2002 | J Bone Miner Res2002，11，： | 1 |
| 18 | Incidence of chemotherapy-induced,long-term amenorrhea in patients with breast carcinoma age 40 years and younger after adjuvant anthracycline and taxane显示文摘 | FORNIER M N MODI S PANAGEAS K S | | 0，，08： | 1 |
| 19 | Serum retinol bindingprotein 4 contributes to insulin resistance in obesity and type 2diabetes显示文摘 | Yang Q Graham TE Mody N | 2005 | Nature2005，436，7049： | 1 |
| 20 | Transcutaneous bilirubin measurement: a multicenter evaluation of a new device显示文摘 | Rubaltelli FF Gourley GR Loskamp N Modi N Roth-Kleiner M Sender A | 2001 | Pediatrics2001，107，6： | 1 |
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