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| 1 | Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors显示文摘从锥蜗牛(Conus ) 的毒液的充满半胱氨酸的肽指向许多不同离子隧道。conopeptides 的一个家庭,伪 - conotoxins,明确地指向在神经与肌的连接和中央神经系统两个都发现的烟碱的醋胆素受体(nAChRs ) 的不同 isoforms。这个家庭进一步基于在半胱氨酸残余之间的氨基酸的数字被划分成亚科。某些伪 - conotoxins 的优美子类型选择对涉及 neurotransmitter 版本的调整的本国的 nAChR isoforms 的描述关键, Parkinson 的疾病和 nociception 的 pathophysiology。伪 - conotoxins 的结构 / 功能描述与改进力量或子类型选择导致了类似物的发展。脊梁结构的环合和脂性的一半的增加导致了伪 - conotoxins 的改进稳定性和 bioavailability,因此为口头上地可得到的治疗学铺平道路。在发展史, exogenomics 和分子的建模诺言的最近的进展有为 nAChRs 的特定的子类型的改进选择的伪 - conotoxins 和类似物的一个甚至更大的数字的发现。 | Layla AZAM J Michael MCINTOSH | 2009 | Acta Pharmacologica Sinica2009，30，6： | 25 |
| 2 | Affirming authenticity显示文摘 | Alison J McIntosh Richard C. Prentice | 1999 | Annals of Tourism Research1999，，3： | 2 |
| 3 | T cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppression显示文摘 | Elena Klyushnenkova Joseph D Mosca Valentina Zernetkina Manas K Majumdar Kirstin J Beggs Donald W Simonetti Robert J Deans Kevin R McIntosh | 2005 | Journal of Biomedical Science2005，，1： | 2 |
| 4 | Ignition properties of thermally thin thermoplastic-the effectiveness of inert additives in reducing flammability显示文摘 | Nelson M I Brindley J McIntosh A C | 1996 | Polym Degrad Stab1996，54，23： | 1 |
| 5 | An efficient, nonen- zymatie method for isolation and culture of murine aortic endothelial cells and their response to inflamma- tory stimuli显示文摘 | Huang H McIntosh J Hoyt D G | 2003 | In Vitro Cell Dev Biol Anim2003，39，1： | 1 |
| 6 | The contribution of flocculated material to shrimp (Litopenaeus vannamei) nutrition in a highintensity zeroexchange system显示文摘 | Burford M Thompson P J McIntosh R P | 2004 | Aquaculture2004，232，1： | 1 |
| 7 | Credit Informatinn Systems In Less-developed Countries:A Test with Microfinance in Guatemala显示文摘 | Luoto J McIntosh C Wydick B | | 0，，55： | 1 |
| 8 | Human mesenchymalstem cells: progenitor cells for cartilage, bone, fat and stroma显示文摘 | Pittenger M F Mocsca J D Mcintosh K R | 2000 | Curt Top Microbiol Immunol2000，251，： | 1 |
| 9 | A numerical study of the vorticity field generated by the baroclinic effect due to the propagation of a planar pressure wave through a cylindrical premixed laminar flame显示文摘 | Batley G A Mcintosh A C Brindley J | 1994 | Journal of Fluid Mechanics1994，279，： | 1 |
| 10 | The critical role ofin-tracellular zinc in adenosine A2 receptor activation induced car-dioprotection against reperfusion injury 显示文摘 | MCINTOSH R LEE S GHIO A J | 2010 | J Mol Cell Cardiol2010，49，1： | 1 |
| 11 | Changes in the microbial population of a rumen-simulating fermenter in response to yeast culture canadian显示文摘 | Newbald C J Mcintosh F M Wallace R J | 1998 | Journal of Animal Science1998，78，2： | 1 |
| 12 | Extensive microbial modificationof formation water geochemistry:Case study from a Midcontinentsedimentary basin,United States显示文摘 | McIntosh J C Walter L M Martini A M | 2004 | Geological Society of America Bulletin2004，116，56： | 1 |
| 13 | Effects of a specific blend of essential oil compounds on rumen fermentation显示文摘 | Newbold C J McIntosh F M Williams P | 2004 | Animal Feed Science and Technology2004，114，14： | 1 |
| 14 | Catalogue of gene symbols for wheat:2006 supplement显示文摘 | McIntosh R A Devos K M Dubcovsky J | 2006 | Annual Wheat Newsletter2006，52，： | 1 |
| 15 | Detection of porcine circovirus type 2 viremia and seroconversion in naturally infected pigs in a farrow-to-finish barn显示文摘 | Mcintosh K A Harding J C Ellis J A | 2006 | Can J Vet Res2006，，70： | 1 |
| 16 | Biogeochemistry of the ForestCity Basin coalbed methane play显示文摘 | McIntosh J Martini A Petsch S | 2008 | International Journal of CoalGeology2008，76，1： | 1 |
| 17 | Allogeneic bone marrow stromal cells promote glial-axonal remodeling without immunologic sensitization after stroke in rats显示文摘 | Li Y McIntosh K Chen J | 2006 | Exp Neurol2006，198，2： | 1 |
| 18 | The contribution of flocculated material to shrimp (Litopenaeus vannamei) nutrition in high-intensity, zero-exchange system 显示文摘 | BURFORD M A THOMPSON P J MCINTOSH P R | 2004 | Aquaculture2004，232，： | 1 |
| 19 | Tourists' appreciation of maori culture in new zealand显示文摘 | MCINTOSH A J | 2004 | Tourism Management2004，，25： | 1 |
| 20 | Role of hydrocarbon deposits in the enhanced performance of direct-oxidation SOFCs 显示文摘 | MCINTOSH S VOHS J M GORTE R J | 2003 | J Electrochem Soc2003，150，4： | 1 |
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