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	题名	作者	年代	出处	被引量
1	Ten years of sorafenib in hepatocellular carcinoma: Are there any predictive and/or prognostic markers?显示文摘Sorafenib has been considered the standard of care for patients with advanced unresectable hepatocellular carcinoma(HCC) since 2007 and numerous studieshave investigated the role of markers involved in the angiogenesis process at both the expression and genetic level and clinical aspect. What results have ten years of research produced? Several clinical and biological markers are associated with prognosis. The most interesting clinical parameters are adverse events, Barcelona Clinic Liver Cancer stage, and macroscopic vascular invasion, while several single nucleotide polymorphisms and plasma angiopoietin-2 levels represent the most promising biological biomarkers. A recent pooled analysis of two phase III randomized trials showed that the neutrophil-to-lymphocyte ratio, etiology and extra-hepatic spread are predictive factors of response to sorafenib, but did not identify any predictive biological markers. After 10 years of research into sorafenib there are still no validated prognostic or predictive factors of response to the drug in HCC. The aim of the present review was to summarize 10 years of research into sorafenib, looking in particular at the potential of associated clinical and biological markers to predict its efficacy in patients with advanced HCC.	Giorgia Marisi Alessandro Cucchetti Paola Ulivi Matteo Canale Giuseppe Cabibbo Leonardo Solaini Francesco G Foschi Serena De Matteis Giorgio Ercolani Martina Valgiusti Giovanni L Frassineti Mario Scartozzi Andrea Casadei Gardini	2018	World Journal of Gastroenterology2018，24，36：	14
2	Analysis of B and T cell clonality and HLA class Ⅱ alleles in patients with idio- pathic thrombocytopenic purpura: correlation with Helico- bacter pylori infection and response to eradication treatment 显示文摘	Veneri D De Matteis G Soler P	2005	Platelats2005，16，5：	1
3	Techniques of laparoscopic myomectomy 显示文摘	Mattei A Cioni R Bargelli G	2011	Reprod Biomed Online2011，23，1：	1
4	Sumatriptan and cerebral biood flow velocity change during migraine attacks显示文摘	Matteis G D Marin C	1997	headache1997，37，10：	1
5	A novel mechanism for thalassaemia intermedia显示文摘	Mattei M G Imbert A M	2002	Lancet2002，359，9301：	1
6	Modeling of lightweight sandwich shear diaphragms for dynamic analyses 显示文摘	Matteis G D Landolfo R	2000	Journal of Constructional Steel Research2000，53，：	1
7	Gene polymorphisms in folate metabolizing enzymes in adult acute lym- phoblastic leukemia: effects on methotrexate - related toxicity and survival显示文摘	ONGARO A DE MATTEI M DELLA PORTA M G	2009	Haematologica2009，94，10：	1
8	Human Igsuperfamily CTLA-4 gene:chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains显示文摘	Dariavach P Mattei M G Golstein P		0，，：	1
9	Marine-derived anticancer agents in clinical trials显示文摘	Schwartsmann G Da Rocha AB Mattei J	2003	Expert Opin Investig Drugs2003，12，8：	1
10	The human 180-kDa receptor for secretory phospholipases A2 : molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization 显示文摘	Ancian P Lambeau G Mattei MG	1995	J Biol Chem1995，270，：	1
11	Boron nitride thin films deposited by RF plasma reactive pulsed laser ablation as interlayer between WC-CO hard metals and CVD diamond films显示文摘	Cappelli E Orlando S Mattei G	2004	Surface and Coatings Technology2004，，：	1
12	Binding of 14-3-3 protein to the plasma membrane H1- ATPase AHA2 involves the three C-terminal residues Tyr946-Thr-Val and requires phosphorylation of Thr947 显示文摘	Fuglsang A Visoonti S Drumm K Jahn T Stensballe A Mattei B Jensen O N Aducci P Palmgren M G	1999	Biol Chem1999，274，36：	1
13	Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22显示文摘	APTE S S MATTEI M G OLSEN B R	1994	Genomics1994，19，1：	1
14	Polygalacturonase-lnhibiting Proteins (PGIPs) with different specificities are expressed in Phaseolus vulgaris 显示文摘	Desiderio A Aracri B Leckie F Mattei B Salvi G Tigelaar H Van Roekel J S C Baulcombe D C Melchers L S De Lorenzo G Cervone F	1997	Molecular Plant-Microbe Interactions1997，10，7：	1
15	Extensive analysis of duplicated-inverted hepatitis B virus integrations in human hepatocellular carcinoma显示文摘	Pineau P Marchio A Mattei M G	1998	J Gen Virol1998，79，3：	1
16	Techniques of laparoscopic my-omectomy显示文摘	Mattei A Cioni R Bargelli G	2011	Reprod Biomed Online2011，23，1：	1
17	Rhabdomyolysis and myalgia associated with anticholesterolemic treatment as potential signs of malignant hyperthermia susceptibility 显示文摘	Guis S Bendahan D Kozak-Ribbens G Figarella- Branger D Mattei JP Pellissier JF	2003	Arthritis Rheum2003，49，2：	1
18	Rotation Capacity of Aluminum Beams under Moment Gradient II:Numerical Simulations显示文摘	MOEN L A MATTEIS G D HOPPERSTAD O S	1999	Journal of Structural Engineering1999，125，8：	1
19	The speciWcity of polygalacturonaseinhibiting protein (PGIP) : a single amino acid substitution in the solvent-exposed β-strand/13-turn region of the leucine-rich repeats (LRRs) conferconfers a new recognition capability 显示文摘	Leckie F Mattei B Capodicasa C Hemmings A Nuss L Aracri B DeLorenzo G Cervone F		The EMBO J0，18，：	1
20	Marine-derived anticancer agents in clinical trials 显示文摘	Schwartsmann G Da Rocha AB Mattei J	2003	Expert Opin Investig Drugs2003，12，8：	1

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