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| 1 | Efficacy of neoadjuvant therapy and surgical rescue for locally advanced hepatoblastomas:10 year single-center experience and literature review显示文摘AIM:To report our experience with long-term outcomes after multimodal management therapy.METHODS:An observational retrospective study was performed containing seven patients with hepatoblastoma(Hbl)treated in our institution,a tertiary referral center,from 2003 to 2011.Demographic,preoperative,surgical,and outcome variables were collected.A survival analysis and a review of the current literature related to combination neoadjuvant chemotherapy and surgical resection on Hbl were performed.RESULTS:The median age at surgery was 14.4 mo,with a male to female ratio of 4:3.Pretext staging at diagnosis was as follows:stageⅠ,4 cases;stageⅡ,2 patients;and stageⅢ,1 case.Mean pretreatment tumor volume was 735 cm3.Five out of seven patients received neoadjuvant chemotherapy according to SIOPEL-3 or SIOPEL-6 protocols.Tumor volume and alphafetoprotein levels significantly dropped after neoadjuvant therapy.Surgical procedures performed included hemihepatectomies,segmentectomies and atypical resection.All patients received chemotherapy after surgery.Median postoperative hospital stay was 8 d.All patients were alive and disease-free after a median follow-up period of 23 mo.With regards to the literature review,seventeen articles were found that were related to our search.CONCLUSION:Our series shows how multimodal management of Hbl,exhaustive control and a meticulous surgical approach leads to almost 100%complete resection with optimal postoperative results. | Dolores Ayllon Teran Oscar Gómez Beltran Rubén Ciria Bru Elena Mateos González María José Pea Rosa Antonio Luque Molina Pedro López Cillero Javier Briceo Delgado | 2014 | World Journal of Gastroenterology2014，20，29： | 12 |
| 2 | Applications of finite element simulation in orthopedic and trauma surgery显示文摘Research in different areas of orthopedic and trauma surgery requires a methodology that allows both a more economic approach and the ability to reproduce different situations in an easy way. Simulation models have been introduced recently in bioengineering and could become an essential tool in the study of any physiological unity, regardless of its complexity. The main problem in modeling with finite elements simulation is to achieve an accurate reproduction of the anatomy and a perfect correlation of the different structures, in any region of the human body. Authors have developed a mixed technique, joining the use of a three-dimensional laser scanner Roland Picza captured together with computed tomography(CT) and 3D CT images, to achieve a perfect reproduction of the anatomy. Finite element(FE) simulation lets us know the biomechanical changes that take place after hipprostheses or osteosynthesis implantation and biological responses of bone to biomechanical changes. The simulation models are able to predict changes in bone stress distribution around the implant, so allowing preventing future pathologies. The development of a FE model of lumbar spine is another interesting application of the simulation. The model allows research on the lumbar spine, not only in physiological conditions but also simulating different load conditions, to assess the impact on biomechanics. Different degrees of disc degeneration can also be simulated to determine the impact on adjacent anatomical elements. Finally, FE models may be useful to test different fixation systems, i.e., pedicular screws, interbody devices or rigid fixations compared with the dynamic ones. We have also developed models of lumbar spine and hip joint to predict the occurrence of osteoporotic fractures, based on densitometric determinations and specific biomechanical models, including approaches from damage and fracture mechanics. FE simulations also allow us to predict the behavior of orthopedic splints applied to the correction of deformities, providing the recovering force-displacement and angle-moment curves that characterize the mechanical behavior of the splint in the overall range of movement. | Antonio Herrera Elena Ibarz José Cego?ino Antonio Lobo-Escolar Sergio Puértolas Enrique López Jesús Mateo Luis Gracia | 2012 | World Journal of Orthopedics2012，3，4： | 8 |
| 3 | Effects of sample pre-treatment on the δ^13C and δ^18O values of living benthic foraminifera显示文摘 | Serrano O Serrano L Mateo M A | 2008 | Chemical Geology2008，257，： | 1 |
| 4 | Accounting for soil variability in the evaluation of furrow irrigation显示文摘 | Oyonarte N A Mateos L | 2003 | Transactions of the American Society of Agricultural Engineers2003，46，1： | 1 |
| 5 | Accounting for soil variability in the evaluation of furrow irrigation显示文摘 | Oyonarte N A Mateos L | 2003 | Transactions of the American Society of Agricultural Engineers2003，46，1： | 1 |
| 6 | A spreadsheet model to evaluate sloping furrow irrigation accounting for infiltration variability显示文摘 | Mateos L Oyonarte N A | | 0，，01： | 1 |
| 7 | Trend Analysis of Monthly PrecipitationOver the Iberian Peninsula for the Period 1921-1995显示文摘 | Serrano V L Mateos V L Garcia J A | 1999 | Physics and Chemis-try of the Earth:B1999，24，2： | 1 |
| 8 | Modernization and optimization of irrigation systems to increase water productive 显示文摘 | Playan E Mateos L | 2006 | Agriculture Water Management2006，80，13： | 1 |
| 9 | Left extended hepatectomy for a metastatic gastroin-testinal strornal tumor after a disease-free interval of 17years:report of a case显示文摘 | MATUSOKA L STAPFER M MATEO R | 2007 | Surg Today2007，37，7： | 1 |
| 10 | Modernization and optimization of irrigation systems to increase water productive显示文摘 | Playan E Mateos L | 2006 | Agricultural Water Management2006，80，13： | 1 |
| 11 | Interferon-gamma release assays in the detection of latent tuberculosis infection in patients with inflammatory arthritis scheduled for anti-tumour necrosis factor treatment显示文摘 | Minguez S Latorre I Mateo L | 2012 | Clin Rheumatol2012，31，： | 1 |
| 12 | Adherens junc- tion protein nectim4 is the epithelial receptor for measles virus 显示文摘 | Mtihlebach M D Mateo M Sinn P L | 2011 | Nature2011，7378，7378： | 1 |
| 13 | Functional amino acids and fatty acids for enhancing production performance of sows and piglets 显示文摘 | KIM S W MATEO R D YIN Y L | 2007 | Asian-Australa- sian Journal of Animal Sciences2007，20，2： | 1 |
| 14 | Tourism partici- pation and expenditure by Spanish households: the effects of the economic crisis and unemployment 显示文摘 | Joaqu l n Alegre Sara Mateo Lloren Pou | 2013 | Tourism Management2013，39，12： | 1 |
| 15 | Line-focused laser ablation for depth-profiling analysis of coated and layered materials 显示文摘 | Mateo M P Cabalin L M Laserna J J | 2003 | Applied Optics2003，42，30： | 1 |
| 16 | Activity-regulated eytoskeleton-associated protein in rodent brain is down-reg ulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro 显示文摘 | Mateos L Akterin S Gil-Bea FJ etal | 2009 | Brain Pathol2009，19，1： | 1 |
| 17 | Study of Span- ish grape mycobiota and ochratoxin A production by isolates of Aspergillus tubingensis and other members of Aspergillus section Nigri显示文摘 | MEDINA A MATEO R L PEZ-OCAA L | 2005 | Applied and Environmental Microbiology2005，71，8： | 1 |
| 18 | Assessing whole-field uniformity of stationary sprinkler irrigation systems 显示文摘 | Mateos L | 1998 | Irrigation Science1998，18，2： | 1 |
| 19 | Sex hormone status and bone mineral density in men with rheumatoid arthritis显示文摘 | Mateo L Nolla JM Bonnin MR | 1995 | Rheumatology1995，22，8： | 1 |
| 20 | Synergism in mixtures of zwitterionic and ionic surfactants 显示文摘 | DIAZ D L MATEOS I G VELAZQUEZ M M | 2005 | Colloids and Surfaces A: Physicochem Eng Aspects2005，，： | 1 |
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