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| 1 | Effects of probiotic bacteria on gastrointestinal motility in guinea-pig isolated tissue显示文摘AIM: To evaluate the intestinal motility changes evoked by 8 bacterial strains belonging to Bifidobacterium , Lactobacillus and Streptococcus genera within the probiotic preparation VSL#3. METHODS: Ileum and proximal colon segments isolated from guinea-pigs were used as a study model. Entire cells and cell fractions (cell debris, cell wall fraction, cytoplasmatic fraction, proteinaceous and non- proteinaceous cytoplasmatic components) of VSL#3 strains and, as controls, Escherichia coli, Salmonella aboni and Bacillus licheniformis were tested in this in vitro model. RESULTS: Among the bacterial cell fractions tested, only the cytoplasmatic fraction modified intestinal motility. Lactobacillus strains stimulated the contraction of ileum segment, whereas all probiotic strains tested induced proximal colon relaxation response. The non-proteinaceous cytoplasmatic components were responsible for the colon relaxation. CONCLUSION: The results obtained in this study suggest that the proximal colon relaxation activity showed by the probiotic bacteria could be one of the possible mechanisms of action by which probiotics exert their positive effects in regulating intestinal motility. | Matteo Massi Pierfranco Ioan Roberta Budriesi Alberto Chiarini Beatrice Vitali Karen M Lammers Paolo Gionchetti Massimo Campieri Anthony Lembo Patrizia Brigidi | 2006 | World Journal of Gastroenterology2006，12，37： | 3 |
| 2 | Inducible nitric oxide synthase activity correlates with lymphangiogenesis and vascular endothelial growth factor-C expression in head and neck squamous cell carcinoma显示文摘 | FRANCHI A MASSI D SANTUCC M I | 2006 | J Pathol2006，208，： | 1 |
| 3 | The Second Follow-up Serial Infusions of Nesiritide(FUSIONII)trial for advanced heart failure:study rationale and designAm显示文摘 | YANCY C W KRUM H MASSIE B M | 2007 | Heart J2007，153，： | 1 |
| 4 | The ganglia distributed monitoring systemz design, implementation, and experience显示文摘 | Massie M L Chun B N Culler D E | 2004 | Parallel Computing2004，30，7： | 1 |
| 5 | TEM-72, a new extended-spectrum β-lactamase detected in Proteus mirabilis and morganella morganii in Italy显示文摘 | Perilli M Segatore B Massis M R D | 2000 | Antimicrob Agents Chemother2000，44，： | 1 |
| 6 | Depression and the cancer patients 显示文摘 | Massie M J Holland JC | 1990 | J Clin Psychiatry1990，51，： | 1 |
| 7 | Effect of amiodarone on clinical status and left ventricular function in patients with congestive heart failure显示文摘 | Massie BM Fisher SG Radford M | 1996 | Circulation1996，93，： | 1 |
| 8 | Depression and the cancer patient显示文摘 | Massie M J Holland JC | 1990 | Clin Psychiatry1990，51，7： | 1 |
| 9 | Silica-based nano-coating on zirconia surfaces using reactive magnetron sputtering:effect on chemical adhesion of resin cements显示文摘 | Queiroz JR Massi M Nogueira L Jr | 2013 | J Adhes Dent2013，15，2： | 1 |
| 10 | The hyperphagic effect of nociceptin/orphanin FQ in rats显示文摘 | Polidori C Caro G Massi M | 2000 | Pepfides2000，21，7： | 1 |
| 11 | Diagnosis and prevention of AIDS显示文摘 | Suligoi B Galli C Massi M | 2002 | J Clin Microbiol2002，40，11： | 1 |
| 12 | Reassessment of dobu-tamine, dopamine, and milrinone in the management of acute heartfailure syndromes显示文摘 | Bayram M De Luca L Massie MB | 2005 | Am J Cardiol2005，96，6： | 1 |
| 13 | The Ganglia Distributed Monitoring System显示文摘 | Massie M L Chun B N Culler D E | 2004 | Parallel Computing2004，30，： | 1 |
| 14 | A one-year,randomised, multicentre trial comparing insulin glargine with NPH insulin in combination with oral agents in patients with type2 diabetes显示文摘 | Massi BM Humburg E Dressler A Ziemen M | 2003 | Horm Metab Res2003，35，3： | 1 |
| 15 | Chronic Renal Allograft Rejection:Immunologic and Nonimmunologic Risk Factors显示文摘 | Massy Z A Guijarro C Wiederkehr M R | 1996 | Kidney Int1996，49，： | 1 |
| 16 | Ascorbic acid in Drosophila and changes during aging显示文摘 | Massie H R Shumway M E Whitney S J P | 1991 | Experimental Gerontology1991，26，5： | 1 |
| 17 | The HITRAN 2008 molecular spectroscopic database 显示文摘 | Rothman L S Gordon I E Barbe A ChrisBenner D Bernath P F Birk M Boudon V Brown L R Campargue A Champi-on J P Chance K Coudert L H Dana V Devi V M Fally S Flaud J M Gamache R R Goldman A Jacquemart D Klein er I Lacome N Lafferty W J Mandin J Y Massie S T Mikhailenko S N Miller C E Moazzen A N Naumenko 0 VNikitin A V Orphal J Perevalov V I Perrin A Predoi C A Rinsland C P Rotger M ime kovd M Smith M A H Sung K Tashkun S A Tennyson J Toth R A Vandaele A C Vander A J | 2009 | Journal of Quantitative Spectroscopy Radiative Transfer2009，110，： | 1 |
| 18 | SNPdetection using peptide nucleic acid probes andconjugated polymers:applications in neurodegenerativedisease identification显示文摘 | Gaylord B S Massie M R Feinstein S C | 2005 | Proceedings of the NationalAcademy of Science of the United States of America2005，102，1： | 1 |
| 19 | Congestive heart failure:current controversies and future prospect显示文摘 | MASSIE B M PACKER M | 1990 | Am J Cardiol1990，66，： | 1 |
| 20 | Depression and the cancer patients显示文摘 | MASSIE M J HOLLAND J C | 1990 | Jclen Psychiatry1990，，： | 1 |
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