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| 1 | Pyogenic liver abscess: Changing patterns in approach显示文摘AIM: To define optimum management of the pyogenic liver abscess and assess new trends in treatment. METHODS: One hundred and sixty nine patients with pyogenic liver abscess managed at Sher-i-Kashmir In- stitute of Medical Sciences, Srinagar, Kashmir (India) from July 2001 to August 2006 were studied to evaluate and define the optimum treatment. RESULTS: Mortality in the surgically treated group of patients was 9.4% (12/119), while those treated non-surgically had a fatality rate of 16.66% (7/42). Multiple liver abscesses treated surgically had a surprisingly low mortality of 30%. The biliary tract (64.97%) was the most common cause of liver abscess. Multiple abscesses, mixed organisms and abscess complications are all associated with a significantly increased mortality. However, the lethality of the primary disease process was the most important factor in determining survival.CONCLUSION: Transperitoneal surgical drainage and antibiotics are the mainstay of treatment. Percutaneous drainage is recommended for high risk patients only. | Ajaz A Malik Shams UL Bari Khawaja Abdul Rouf Khurshid Alam Wani | 2010 | World Journal of Gastrointestinal Surgery2010，2，12： | 15 |
| 2 | 施工总承包模式下建筑供应链成本管理优化决策模型研究显示文摘建筑供应链成本控制是建筑企业和业主进行工程项目管理的关键内容,在大型城市建设项目管理中尤其重要。本文分析了以施工总承包商为核心的建筑供应链的结构和特征,构建了该类建筑供应链的结构模型,对供应链中建筑材料供给、运输、劳务与专业分包、建筑产品建造等环节的费用情况进行详细分析;在考虑到运输商运输能力、供应商供给能力、分包商建造能力等约束的基础上,建立了以施工总包商为核心的建筑供应链成本的多因素综合决策优化模型,最后对模型的应用进行了案例分析,结果表明该模型对施工总承包模式下建筑供应链成本优化决策具有较好的指导性、实用性和可拓展型。 | 李先光 李启明 刘颖 Khalfan Malik M A | 2009 | 华中科技大学学报(城市科学版)2009，26，1： | 12 |
| 3 | 长期食用含糖和人工甜味剂的饮料与美国成年人死亡风险的关系显示文摘摄入含糖饮料(sugar-sweetened beverages,SSB)或含人工甜味剂饮料(artificially sweetened beverages,ASB)是否与死亡风险相关,这关乎公共卫生利益。研究者分析了卫生专业人员随访研究(1986-2014年)中男性37 716人和护士健康研究(1980-2014年)中女性80 647人(基线无慢性病)的SSB和ASB的消费与总死亡率和病因特异性死亡率之间的关系。应用Cox比例风险回归估计风险比和95%CI。结果显示,在随访3415564人年期间,研究者记录了36436例死亡,其中心血管病死亡7896例,癌症死亡12380例。 | 刘青(译) 叶鹏(摘、审校) Malik VS Li Y Pan A De Koning L Schernhammer E Willett WC Hu FB | 2019 | 中华高血压杂志2019，27，5： | 9 |
| 4 | 在良性的胆汁的阻塞的 choledochoduodenostomy 的长期的结果显示文摘 AIM:To determine the long-term results of choledochodudenostomy in patients with benign billiary obstruction.METHODS:This prospective study was conducted at Sheri Kashmir Institute of Medical Sciences Srinagar Kashmir,India over a period of 10 years from January 1997 to December 2007.The total number of patients who underwent choledochoduodenostomy during this period was 270.On the basis of etiology of biliary tract obstruction,patients were divided into a calculus group,an oriental cholangiohepatitis group,a benign biliary stricture group and others.Patients were followed for a variable period of 13 mo to 15 years.RESULTS:Choledochoduodenostomy(CDD) with duodenotomy was performend in four patients.CDD with removal of T-tube,CDD with left hepatic lobectomy and CDD with removal of intra biliary ruptured hydatid was performed in three patients each.In the remaining patients only CDD was performed.Immediate post operative complications were seen in 63(23%) patients,while long-term complications were seen in 28(11%) patients,which were statistically significant.Three patients died during hospitalization while four patients died in the late post-operative period.CONCLUSION:Our conclusion is that CDD is safe and produces good long term results when a permanent biliary drainage procedure is required. | Ajaz A Malik Shiraz A Rather Shams UL Bari Khursheed Alam Wani | 2012 | World Journal of Gastrointestinal Surgery2012，4，2： | 7 |
| 5 | In vivo corneal confocal microscopic analysis in patients with keratoconus显示文摘AIM: To quantify corneal ultrastructure using laser scanning in vivo confocal microscopy(IVCM) in patients with keratoconus and control subjects. METHODS: Unscarred corneas of 78 keratoconic subjects without a history of contact lens use and 36age-matched control subjects were evaluated with slit-lamp examination(SLE), corneal topography and laser scanning IVCM. One eye was randomly chosen for analysis. Anterior and posterior stromal keratocyte,endothelial cell and basal epithelial cell densities and sub-basal nerve structure were evaluated.RESULTS: IVCM qualitatively demonstrated enlarged basal epithelial cells, structural changes in sub-basal and stromal nerve fibers, abnormal stromal keratocytes and keratocyte nuclei, and pleomorphism and enlargement of endothelial cells. Compared with control subjects, significant reductions in basal epithelial cell density( 5817 ± 306 cells / mm2 vs 4802 ±508 cells/mm2,P < 0. 001), anterior stromal keratocyte density(800 ±111 cells/mm2 vs 555 ±115 cells/mm2, P <0.001),posterior stromal keratocyte density(333±34 cells/mm2vs270 ±47 cells/mm2, P <0.001), endothelial cell density(2875 ±223 cells/mm2 vs 2686 ±265 cells/mm2, P <0.001),sub-basal nerve fiber density(31.2 ±8.4 nerves/mm2vs18.1 ±9.2 nerves/mm2, P <0.001), sub-basal nerve fiber length(21.4±3.4 mm/mm2 vs 16.1±5.1 mm/mm2, P <0.001),and sub-basal nerve branch density(median 50.0(first quartile 31.2- third quartile 68.7) nerve branches/mm2 vs median 25.0(first quartile 6.2- third quartile 45.3) nerve branches/mm2, P <0.001) were observed in patients with keratoconus.CONCLUSION: Significant microstructural abnormalities were identified in all corneal layers in the eyes of subjects with keratoconus using IVCM. This non-invasive in vivo technique provides an important means to define and follow progress of microstructural changes in patients with keratoconus. | Gulfidan Bitirgen Ahmet Ozkagnici Banu Bozkurt Rayaz A Malik | 2015 | International Journal of Ophthalmology(English edition)2015，8，3： | 6 |
| 6 | Surgical management of complicated hydatid cysts of the liver显示文摘AIM: To review the clinical presentation and surgical management of complicated hydatid cysts of the liver and to assess whether conservative surgery is adequate in the management of complicated hydatid cysts of liver.METHODS:The study was carried out at Sher-i-Kashmir Institute of Medical Science,Srinagar,Kashmir,India.Sixty nine patients with hydatid disease of the liver were surgically managed from April 2004 to October 2005 with a follow up period of three years.It included 27 men and 42 women with a median age of 35 years.An abdominal ultrasound,computed tomography and serology established diagnosis.Patients with jaundice and high suspicion of intrabiliary rupture were subjected to preoperative endoscopic retrograde cholangiography.Cysts with infection,rupture into the biliary tract and peritoneal cavity were categorized as complicated cysts.Eighteen patients(26%)had complicated cysts and formed the basis for this study.RESULTS:Common complications were infection(14%),intrabiliary rupture(9%)and intraperitoneal rupture(3%).All the patients with infected cysts presented with pain and fever.All the patients with intrabiliary rupture had jaundice,while only four with intrabiliary rupture had pain and only two had fever.Surgical procedures performed in complicated cysts were:infection-omentoplasty in three and external drainage in seven;intrabiliary rupture-omentoplasty in two and internal drainage in four patients.Two patients with intraperitoneal rupture underwent external drainage.There was no mortality.The postoperative morbidity was 50%in complicated cysts and 16%in uncomplicated cysts.CONCLUSION:Complicated hydatid cyst of the liver can be successfully managed surgically with good long term results. | Ajaz A Malik Shams UL Bari Ruquia Amin Masooda Jan | 2010 | World Journal of Gastrointestinal Surgery2010，2，3： | 4 |
| 7 | 利用抗高血压药相关的遗传变异发现其潜在的功效和副作用显示文摘通过研究药物靶蛋白基因的自然变异可以了解药物的功效。本研究旨在利用这种方法探索抗高血压药的潜在副作用和再利用潜力。研究者首先确定了血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitor,ACEI)、β受体阻滞剂和钙拮抗剂的合适代表基因。 | 刘青(译) 叶鹏(校) Gill D Georgakis MK Koskeridis F Jiang L Feng Q Wei WQ Theodoratou E Elliott P Denny JC Malik R Evangelou E Dehghan A Dichgans M Tzoulaki I | 2019 | 中华高血压杂志2019，0，9： | 3 |
| 8 | Facilitation of adrengic transmission by locally generated angiotensin Ⅱ in rat mesentic arties显示文摘 | Malik KU Nasiletti A | 1976 | Cire Res1976，38，： | 2 |
| 9 | Transperineurial capillary abnormalities in the sural nerve of patients with diabetic neuropathy显示文摘 | MALIK R A TESFAGE S THOMPSON S D | 1994 | Microvasc Res1994，48，2： | 2 |
| 10 | The Early Restart Algorithm显示文摘 | MALIK M AMIR F A | 2000 | Neural Computation MIT2000，，12： | 2 |
| 11 | Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion显示文摘 | Rahman A Anwar KN True AL Malik AB | 1999 | J Immunol1999，162，： | 1 |
| 12 | Multi-way partial least squares modeling of water quality data显示文摘 | Singh K P Malik A Basant N | 2007 | Analytica Chimica Acta2007，，584： | 1 |
| 13 | α-Glucosidase inhibitory constituents from Duranta repens 显示文摘 | Iqbal K Malik A Mukhtar N | 2004 | Chem Pharm Bull2004，52，7： | 1 |
| 14 | Acute myocardial infarction following tranexamic acid use in a low cardiovascular risk setting显示文摘 | SIRKER A MALIK N BALLAMY M | 2008 | Br J Haematol2008，141，6： | 1 |
| 15 | Changes in intraocular pressure and anterior segment morphometry after uneventful phacoemulsification cataract surgery 显示文摘 | Dooley I Charalampidou S Malik A | 2010 | Eye (Lond)2010，24，4： | 1 |
| 16 | Turbulence dynamics: an independent predictor of late mortality after myocardial infarction显示文摘 | Bauer A Malik M Barthel P | 2006 | Int J Cardiol2006，107，1： | 1 |
| 17 | Hepatitis B therapy:the plot thickens显示文摘 | MALIK A H LEE W M | 1999 | Hepatology1999，30，2： | 1 |
| 18 | Dry eye:prevalence and attributable risk factors in a hospital-based population 显示文摘 | Sahai A Malik P | 2005 | Indian J Ophthalmol2005，53，2： | 1 |
| 19 | Corrosion failure of bottom plates of an above ground storage tank 显示文摘 | Mobin M Malik A U Al-Fozan S | 2007 | Journal of Failure Analysis and Prevention2007，7，1： | 1 |
| 20 | Small cell neuroendocrine carcinoma of the endometrium,a rare aggressive tumor 显示文摘 | Rajab KE Sandhu AK Malik A | 2005 | Saudi Med J2005，26，7： | 1 |
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