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729篇 您的检索式:作者名="M Mandel"
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1Increase of beta-amyloid and C-reactive protein in liver transplant recipients with postoperative cognitive dysfunction显示文摘BACKGROUND: Postoperative cognitive dysfunction (POCD) is an adverse condition characterized by declined cognitive functions following surgeries and anesthesia. POCD has been associated with increased hospital stay and mortality. There are histological similarities to Alzheimer's disease. Most early studies were conducted in patients receiving cardiac surgery. Since there is no information about POCD in liver transplant recipients, we measured the incidence of POCD in patients after liver transplantation and examined the correlation between neurological dysfunction and biological markers of dementia- based diseases. METHODS: We studied 25 patients who had a liver transplan- tation between July 2008 and February 2009. Patients with prior encephalopathy or risk factors associated with the development of POCD were excluded from the study. Five validated neuropsychiatric tests were used for diagnosis. The diagnosis was based on one standard deviation decline in two of the five neuropsychiatric tests. The correlation between patient variables and the development of POCD was examined. Serum levels of beta-amyloid and C-reactive protein were measured by standard ELISA and compared between patients with and without POCD. RESULTS: POCD was present in 11 (44%) of the 25 patients. Patients with POCD had significantly higher MELD scores, were more often Child-Pugh class C and received more blood transfusion during surgery. The serum beta-amyloid protein and C-reactive protein concentrations were significantly increased at 24 hours after surgery in the POCD group.CONCLUSIONS: The incidence of POCD in our group of liver transplant patients was greater than that reported in other surgical patients. The increase in the serum biomarkers of dementia in the POCD patients supports the hypothesis that chronic cognitive defects are due to a process similar to that seen in Alzheimer's disease.Xing Li Da-Xiang Wen Yan-Hong Zhao Yan-Nan Hang M Susan Mandell 2013Hepatobiliary & Pancreatic Diseases International2013,12,4:13
2Recent advances in cellulose technology显示文摘Mandel M Steinberg D 1976Journal of Fermentation Technology1976,54,4:1
3Molecular Characterization of the Arabidopsis Floral Homeotic Gene APETALAI显示文摘Mandel M Gustason Brown C Savidge B 1992Nature1992,360,:1
4An error analysis of failure prediction techniques derived from fracture mechanics 显示文摘Wiederhom S M Fuller E R Mandel J 1976Journal of the American Ceramic Society1976,59,910:1
5Patterns of lateral neck metastasis in papillary thyroid carcinoma显示文摘Kupferman ME Patterson M Mandel SJ 2004Arch Otolaryngol Head Neck Surg2004,130,:1
6Dopaminergic transplants normalize amphetamine-and apomorphine-induced Fos expression in the 6-hydroxydopamine-lesioned striatum显示文摘Cenci M A Kalen P Mandel R J 1992Neuroscienee1992,46,:1
7Deoxyribonucleic acid base composition of isolates of the genus Chlorobium 显示文摘Mandel M Bergendahl JC Fennig NP 1965Bacteriology1965,89,3:1
8Calcium-dependent bacteriophage DNA infection显示文摘Mandel M Higa A 1970J Mol Biol1970,53,1:1
9Measurement of saccharifying cellulase显示文摘MANDEL S M 1976Biotechnol Bioeng1976,6,:1
10Induction of cellulase in fungi by cellobiose 显示文摘MANDEL M REESE E T 1960Bacteriology1960,79,6:1
11Molecu- lar characterization of the Arabidopsis floral homeotic gene APETELA1 显示文摘Mandel M A Gustafson-Brown C Savidge B 1992Nature1992,360,6401:1
12The Arabidopsis AGL8 MADS-box gene is expressed in inflorescence mer- istems and is negatively regulated by APETALA1 显示文摘MANDEL M A YANOFSKY M F 1995Plant Cell1995,7,:1
13Measurement of saccharifying cellulose显示文摘Mandels M Andreott R E Rochei C H 1976Biotechnology Bioen- gineering Symposium1976,6,:1
14Effects of music therapy and music-assisted relaxation and imagery on health-relat- ed outcomes in diabetes education: a feasibility study显示文摘Mandel SE Davis BA Secic M 2013Diabetes Educ2013,39,4:1
15Recent advance in cellulase technology 显示文摘MANDELS M STERNBERG D 1976J Ferment Technol1976,54,:1
16Enzymatic hydrolysis of cellulose: Evaluation of cellulase culture filtrates under use conditions显示文摘MANDELS M MEDEIROS J E ANDREOTTI R E 1981Biotechnology and Bioengineering1981,23,9:1
17Quantum phase transition from a Super fluid to a Mott insulator in a gas of ultracold atoms显示文摘GREINER M MANDEL O ESSLINGER T 2002Nature ( London )2002,39,:1
18Production of Trichoderma reesei cellulase system with high hydrolytic potential by solid-state fermentation 显示文摘Chahal DS Mandels M Kohlmann K 1991Enzymes in Biomass Conversion ACS Symposium Series1991,460,:1
19TheArabidopsis AGL8 MADS box gene is expressed in inflorescence meristems and is nega- tively regulated by APETALA 1 显示文摘Mandel A M Yanofsky M F 1995The Plant Cell1995,7,11:1
20Measurement of saccharifying cellulase显示文摘Mandels M Andreotti R Roche C 0,,06:1
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