维普中文期刊产品整合服务
190篇 您的检索式:作者名="M ISA"
    题名 作者 年代 出处 被引量
1二硫戊环衍生物和类似物的合成及其iNOS/PAF双重抑制剂活性(英文)显示文摘目的 :研究双重作用的新型抗炎药物。方法 :合成二硫戊环衍生物和类似物 ,研究这些化合物及选择性的PAF受体拮抗剂L6 5 9,989对PAF受体的结合 ,和对IFN γ或LPS诱导的NO生成 ,以及对iNOSmRNA表达的影响。结果 :合成了 4 0个新化合物 ,其中 19个在不同程度上抑制NO生成。选择 3个活性最高的化合物 (2 ,19,2 0 )进行深入研究 ,发现它们能抑制iNOSmRNA的表达 ,其抑制NO生成的效力从高到低依次为 :19,2 0 ,2 ,L6 5 9,989,其拮抗PAF受体的活性从高到低依次为 :L6 5 9,989,2 0 ,2 ,19。L6 5 9,989对NO生成和iNOSmRNA表达无影响。受试物的PAF受体拮抗活性与iNOS抑制活性之间无简单关联。结论 :二硫戊环类化合物是iNOS表达的新型调控剂 ,其中一些具有抑制iNOS的诱导和拮抗PAF受体的双重活性。张奕华 HUSSAINI Isa M SHEN Tsung Y 2003中国药科大学学报2003,34,3:2
2Adaptive fuzzy-K-means clus-tering algorighm for image segmentation显示文摘Sulaiman S N Isa N A M 2010IEEE Trans on Consumer Electronics2010,56,4:1
3Cluster-based adaptive fuzzy switching median filter for universal impulse noise reduc- tion显示文摘Toh K K V Isa N A M 2010IEEE Transactions on Consumer Electronics2010,56,4:1
4A GA-based feature selection and parameter optimization of an ANN in diagnosing breast cancer 显示文摘AHMAD F ISA N A M HUSSAIN Z 2014Pattern Analysis and Applications2014,18,4:1
5Membrane mediated assembly of annexins studied by site-directed spin labeling显示文摘Langen R Isas J M Luecke H 1998J BiolChem1998,273,:1
6Adaptive fuzzy-K-means clustering algorithm for image segmentation显示文摘SULAIMAN S N ISA N A M 2010IEEE Transactions on Consumer Electronics2010,56,4:1
7Adaptive fuzzy moving k-means clustering algorithm for image segmentation 显示文摘Isa N A M Salamah S A Ngah U K 2009IEEE Transactions on Consumer Electronics2009,55,4:1
8Color image segmentation using histogram thresholding-Fuzzy C-means hybrid ap- proach 显示文摘Tan K S Isa N A M 2011Pattern Recognition2011,,44:1
9Natural progression of untreated hepatolithiasis that shows no clinical signs at its initial presentation 显示文摘KUSANO T ISA T OHTSUBO M 2001J Clin Gastroenterol2001,33,2:1
10M2 macrophages exhibithigher sensitivity to oxLDL-induced lipotoxicity than othermonocyte/macrophage subtypes显示文摘Isa SA Ruffino JS Ahluwalia M 2011Lipids Health Dis2011,10,:1
11Hypoxia in head and neck cancer 显示文摘ISA A Y WARD T H WEST C M 2006Brit J Radiol2006,79,946:1
12Drug-sensitivity profile of clinical Mycobacterium tuberculosis isolates-a retrospective study from a chest-disease institute in India显示文摘Dam T Isa M Bose M 2005J Med Microbiol2005,54,3:1
13Synthesis of polyhydroxyalkanoates from different short-chain fatty acids by mixed cultures submitted to aerobic dynamic feeding显示文摘Paulo C Lemos Lu'isa S S Maria A M R 2006Journal of Biotechnology2006,122,:1
14Denoising-based clustering algo- rithms for segmentation of low level Salt-and-Pepper noise-corrupted images显示文摘Sulaiman S N Isa N A M 2010IEEE Transactions on Consumer Electronics2010,56,4:1
15Adaptive fuzzy-K-means clustering algorithm for image segmentation 显示文摘Sulaiman S N Isa N A M 2010IEEE Transactions on Consumer Electronics2010,56,14:1
16Modified recursive least squares algorithm to train the hybrid multilayered perceptron(HMLP) network 显示文摘AL-BATAH M S ISA N A M ZAMLI K Z 2010Applied Soft Computing2010,10,1:1
17Drug-sensitivity profile of clinical Mycobacterium tuberculosis isolates-a retrospective study from a chest-disease institute in India显示文摘Dam T Isa M Bose M 2005Med Microbiol2005,54,3:1
18Factors influencing tourist visitation in marine tourism: lessons learned from FRI Aquarium Penang, Malaysia显示文摘ISA M S RAMLI L 2014International Journal of Culture Tourism and Hospitality Research2014,8,1:1
19A further study of the recovery and purification of surfactin from fermentation broth by membrane filtration显示文摘Isa M H M Frazier R A Jauregi P 2008Separation and Purification Technology2008,64,2:1
20Noise adaptive fuzzy switching median filter for salt-and-pepper noise reduction 显示文摘Toh K K V Isa N A M 2010IEEE Signal Pro- cessing Letters2010,17,3:1
返回顶部 每页显示:
共10页 首页 上一页 第1页 下一页 末页 /10 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费