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| 1 | Multimodality functional imaging using DW-MRI and 18F-FDG-PET/CT during radiation therapy for human papillomavirus negative head and neck squamous cell carcinoma: Meixoeiro Hospital of Vigo Experience显示文摘AIM To noninvasively investigate tumor cellularity measured using diffusion-weighted magnetic resonance imaging(DW-MRI) and glucose metabolism measured by 18 Flabeled fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG-PET/CT) during radiation therapy(RT) for human papillomavirus negative(HPV-) head and neck squamous cell carcinoma(HNSCC).METHODS In this prospective study, 6 HPV- HNSCC patients underwent a total of 34 multimodality imaging examinations(DW-MRI at 1.5 T Philips MRI scanner [(n = 24) pre-, during-(2-3 wk), and post-treatment(Tx), and 18F-FDG PET/CT pre- and post-Tx(n = 10)]. All patients received RT. Monoexponential modeling of the DW-MRI data yielded the imaging metric apparent diffusion coefficient(ADC) and the mean of standardized uptake value(SUV) was measured from 18F-FDG PET uptake. All patients had a clinical follow-up as the standard of care and survival status was documented at 1 year.RESULTS There was a strong negative correlation between the mean of pretreatment ADC(ρ =-0.67, P = 0.01) and the pretreatment 18F-FDG PET SUV. The percentage(%) change in delta(?) ADC for primary tumors and neck nodal metastases between pre- and Wk2-3 Tx were as follows: 75.4% and 61.6%, respectively, for the patient with no evidence of disease, 27.5% and 32.7%, respectively, for those patients who were alive with disease, and 26.9% and 7.31%, respectively, for those who were dead with disease.CONCLUSION These results are preliminary in nature and are indicative, and not definitive, trends rendered by the imaging metrics due to the small sample size of HPV- HNSCC patients in a Meixoeiro Hospital of Vigo Experience. | David Aramburu Núnez Antonio Lopez Medina Moisés Mera Iglesias Francisco Salvador Gomez Abhay Dave Vaios Hatzoglou Ramesh Paudyal Alfonso Calzado Joseph O Deasy Amita Shukla-Dave Victor M Munoz | 2017 | World Journal of Radiology2017，9，1： | 2 |
| 2 | Perspectives on model based integration of process operation显示文摘 | Bassett M H Dave P Doyle F J III | 1996 | Computers & Chem Eng1996，20，67： | 2 |
| 3 | A Wheel Set Crossing Model Regarding Impact,Sliding and DeformationExplicit Finite Element Approach显示文摘 | PLETZ M DAVES W OSSBERGER H | 2012 | Wear2012，294，3： | 1 |
| 4 | Heuristic filtering,reliable calibration methods for vid-eo-based pupil-tracking systems显示文摘 | Dave M Stampe | 1993 | Behavior Research Methods1993，25，2： | 1 |
| 5 | A model for resinflow during composite processing: Part 1-General mathe-matical development 显示文摘 | Dave R Kardos J L Dudukovic M P | 1987 | Polymer Composites1987，8，1： | 1 |
| 6 | Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate 显示文摘 | Ved H Koenig M L Dave J R | 1997 | Neuro Report1997，8，4： | 1 |
| 7 | 9q34 rearrangements in BCR/ABL fusion-negative acute lymphoblastie leukemia 显示文摘 | Dave BJ Wiggins M Higgins CM | 2005 | Cancer Genet Cytogenet2005，162，1： | 1 |
| 8 | Friction processes benefit from a gas shied显示文摘 | Thomas W M Dave Nicholas Richard Wiktorgwiz | 1998 | Welding & Metal Fabrication1998，，5： | 1 |
| 9 | Fromthe bird's eye to the microscope: A survey of new styli- zed facts of the intradaily foreign exchange markets显示文摘 | Guillaume D M Dacorogna M M Dave R | 1997 | Finance and Stochastics1997，1，2： | 1 |
| 10 | Composition and operation of hydrogen-selective amorphous alloy membranes显示文摘 | DOLAN M D DAVE N C ILYUSHECHKIN A Y MORPETH L D MCLENNAN K G | 2006 | Journal of Membrane Science2006，285，： | 1 |
| 11 | The phosphorylation pattern of IGFBP-1 in normal plama is different from that in Am niotice Fluid and changes duging pregnancy 显示文摘 | Westwood R Gibson M J Daves A J | 1994 | J Clin Endocrinol Metab1994，79，6： | 1 |
| 12 | Phytochemical determination and extraction of Momordica Charantia fruit and its hypoglycemic potentiation of oral hypoglycemic drugs in diabetes mellitus (NIDDM) 显示文摘 | Tongia A Tongia S Dave M | 2004 | J Physiol & Pharm2004，48，： | 1 |
| 13 | Liquid crystalline, rheological and thermal properties of konjac glucomannan 显示文摘 | Dave V Sheth M McCarthy S P | 1998 | Polymer1998，39，5： | 1 |
| 14 | Gastric teratoma in children显示文摘 | Gapta DK Srinivas M Dave S | 2000 | Pediatr Surg Int2000，16，56： | 1 |
| 15 | Association between Helico- bacter pylori infection and inflammatory bowel disease: a meta-anal- ysis and systematic review of the literature 显示文摘 | Luther J Dave M Higgins PD | 2010 | Inflamm Bowel Dis2010，16，6： | 1 |
| 16 | A study of the physical sta- bility of wet media-milled fenofibrate suspensions using dynamic equilibrium curves 显示文摘 | Knikek C Azad M A Dave R N | 2013 | Chem Engineer Res Design2013，91，7： | 1 |
| 17 | Determination of Therapeutic and Growth Promoting Use of Clenbuterol by Plasma Analysis显示文摘 | Blass A Dave M Fallon R J | 1999 | J Vet Pharmacol Ther1999，22，： | 1 |
| 18 | Identification of a proliferation signature related to survival in nodal peripheral T-cell lymphomas显示文摘 | Cuadros M Dave SS Jaffe ES | 2007 | J Clin Oncol2007，25，22： | 1 |
| 19 | Design and analysis of a fuzzy proportional-integral-derivative controller显示文摘 | Dave M Heidar A M Guanrong C | 1996 | Elsevier Science on Fuzzy Sets and Systems1996，79，： | 1 |
| 20 | 800 nA process-and-vohage-invariant 106-dB PSRR PTAT current refer- ence 显示文摘 | AMARAVATI A DAVE M BAGHINI M S | 2013 | IEEE Transactions on circuits and systems II: Ex- press Briefs2013，60，9： | 1 |
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