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| 1 | Prevalence and correlates of depressive symptoms in adult patients with pulmonary tuberculosis in the Southwest Region of Cameroon显示文摘Background:Tuberculosis(TB)remains a global health challenge and depression is a significant contributor to the global burden of disease.Current evidence suggests that there is an association between depressive symptoms and TB,lower adherence to treatment,and increased morbidity and mortality.However,there is paucity of data regarding these associations in Cameroon.This study aimed to determine the prevalence and correlates of depression in adult patients with pulmonary TB(PTB)in the Southwest Region of Cameroon.Methods:A hospital-based cross-sectional study involving 265 patients with PTB was conducted from 2nd January to 31st March 2015 in the Limbe Regional Hospital and the Kumba District Hospital.Depression was diagnosed using the standard nine-item Patient Health Questionnaire,and classified as none,mild or moderate.Logistic regressions were used to investigate correlates of depression in these patients.Results:Of the 265 patients(mean age 36.9±10 years)studied,136(51.3%)were female.The prevalence of depression was 61.1%(95%CI:55.1–66.8),with a significant proportion(36.6%)having mild depression.Multivariable logistic regression analysis showed that being female(aOR=3.0,95%CI(1.7–5.5),P<0.001),having a family history of mental illness(aOR=2.5,95%CI:1.3–5.4,P>0.05),being on retreatment for TB(aOR=11.2,95%CI:5.2–31.1,P<0.001),having discontinued treatment(aOR=8.2,95%CI:1.1–23.3,P<0.05)and having a HIV/TB co-infection(aOR=2.5,95%CI:1.2–6.5,P<0.001)were factors associated with having a higher chance of being depressed.Conclusion:Our study suggests that there is a high prevalence of depression among PTB patients,with more than one in two patients affected.Multidisciplinary care for TB patients involving mental health practitioners is highly encouraged,especially for high-risk groups. | Jules Kehbila Cyril Jabea Ekabe Leopold Ndemnge Aminde Jean Jacques NNoubiap Peter Nde Fon Gottlieb Lobe Monekosso | 2016 | Infectious Diseases of Poverty2016，5，1： | 3 |
| 2 | Pulsatile administration of the epidermal growth factor receptor inhibitor gefitinib is significantly more effective than continuous dosing for sentitizing tumors to paclitaxel显示文摘 | Solit DB She Y Lobe J | 2005 | clin cancer Res2005，11，： | 1 |
| 3 | US-guided automated largecore breast biopsy显示文摘 | Parker SH lobe WE Dennis MA | 1993 | Radiology1993，187，2： | 1 |
| 4 | Fundamental indexing around the world 显示文摘 | Walkshusl C Lobe S | 2010 | Review of Financial Economics2010，19，3： | 1 |
| 5 | Laparosoopic Duhamel pullthrough procedure for Hirschsprung's disease in childhood显示文摘 | Smith BM Steiner RB Lobe TE | 1994 | J Laparoendosc Surg1994，4，4： | 1 |
| 6 | Kumar N, Immunization of mice with DNA-based Pfs25 elicits potent malaria transmissionblocking antibodies显示文摘 | Lobe CA Dhar R | 1999 | Infect Immun1999，67，4： | 1 |
| 7 | Laparoscopic Duhamel pull- through procedure for Hirschsprung's disease in childhood显示文摘 | Smith BM Steiner RB Lobe TE | 1994 | J Laparoendosc Surg1994，4，4： | 1 |
| 8 | Contribution of the Helix- Loop-Helix factor Id2 to regulation of vascular smooth muscle cell proliferation 显示文摘 | Matsumura M lobe DR McNamara CA | 2002 | J Biol Chem2002，277，9： | 1 |
| 9 | Hepatomaderived growth factor stimulates smooth muscle cell growth and is expressed in vascular development 显示文摘 | Everett AD Lobe DR Matsumura ME | 2000 | J Clin Invest2000，105，5： | 1 |
| 10 | Laparoscopic Duhamel pullthrough procedure for Hirschsprung's disease in childhood显示文摘 | Steiner RB Lobe TE | 1994 | J Laparosc Surg1994，4，： | 1 |
| 11 | Early definitive intervention by thoracoscopy in pediatric empyema 显示文摘 | Merry CM Bufo AJ Shah RS Schropp KP Lobe TE | 1999 | J Pediatric Surg1999，34，1： | 1 |
| 12 | Laparoscopic surgery in children 显示文摘 | Lobe TE | 1998 | Current Problem in Surgery1998，35，10： | 1 |
| 13 | Laparoscopic Duhamel pull- through procedure for Hirschsprung's disease in childhood 显示文摘 | Smith BM Steiner RB Lobe TE | 1994 | J Laparoendosc Surg1994，4，4： | 1 |
| 14 | Thoraeoseopie repair of esophageal atresia in an infant:a SurgiCal first显示文摘 | Lobe TE Rothenberg S Waldsehmidt J | 1999 | Pediatric en- dosurgery & innovative techniques1999，3，3： | 1 |
| 15 | A randomized controlled trial of surgery for temporal-lobe epilepsy显示文摘 | Blume WT Girvin JP Eliasziw M and the Effectiveness and Efficiency of Surgery for Temporal Lobe Epilepsy Study Group | 2001 | N Engl J Med2001，345，： | 1 |
| 16 | The importance of diagnosing the polycystic ovary syndrome显示文摘 | Lobe RA Carmina E | 2000 | Ann Intern Med2000，132，12： | 1 |
| 17 | Glypican3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling显示文摘 | Capurro MI Xiang YY Lobe C | 2005 | Cancer Research2005，65，： | 1 |
| 18 | Abdominal aortic surgery in the presence of a horseshoe kidney显示文摘 | Lobe TE Martin EW Cooperman M | 1978 | Ann Surg1978，188，1： | 1 |
| 19 | Biodegradation of bisphernol aand other bisphenols by a gram-negative aerobic bacterrum显示文摘 | Lobes J H Leib T K Su T M | 1992 | Applied Environmental Microbiology1992，58，： | 1 |
| 20 | Laparoscopic Duhamel pull-through procedure for Hirschsprung's disease in childhood显示文摘 | Smith BM Steiner RB Lobe TE | 1994 | J Laparosc Surg1994，4，4： | 1 |
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