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703篇 您的检索式:作者名="Linge N"
    题名 作者 年代 出处 被引量
1Stability theory for hybrid dynamical systems显示文摘YE Hong Michel A N HOU Ling 0,,:2
2In vivo evaluation of additively manufacturedmulti-layered scaffold for the repair of large osteochondral defects显示文摘The repair of osteochondral defects is one of the major clinical challenges in orthopaedics.Well-established osteochondral tissue engineering methods have shown promising results for the early treatment of small defects.However,less success has been achieved for the regeneration of large defects,which is mainly due to the mechanical environment of the joint and the heterogeneous nature of the tissue.In this study,we developed a multi-layered osteochondral scaffold to match the heterogeneous nature of osteochondral tissue by harnessing additive manufacturing technologies and combining the established art laser sintering and material extrusion techniques.The developed scaffold is based on a titanium and polylactic acid matrix-reinforced collagen“sandwich”composite system.The microstructure and mechanical properties of the scaffold were examined,and its safety and efficacy in the repair of large osteochondral defects were tested in an ovine condyle model.The 12-week in vivo evaluation period revealed extensive and significantly higher bone in-growth in the multi-layered scaffold compared with the collagen–HAp scaffold,and the achieved stable mechanical fixation provided strong support to the healing of the overlying cartilage,as demonstrated by hyaline-like cartilage formation.The histological examination showed that the regenerated cartilage in the multi-layer scaffold group was superior to that formed in the control group.Chondrogenic genes such as aggrecan and collagen-II were upregulated in the scaffold and were higher than those in the control group.The findings showed the safety and efficacy of the cell-free“translation-ready”osteochondral scaffold,which has the potential to be used in a one-step surgical procedure for the treatment of large osteochondral defects.Maryam Tamaddon Gordon Blunn Rongwei Tan Pan Yang Xiaodan Sun Shen-Mao Chen Jiajun Luo Ziyu Liu Ling Wang Dichen Li Ricardo Donate Mario Monzón Chaozong Liu 2022Bio-Design and Manufacturing2022,5,3:2
3Direct numerical simulation of a three-dimensional temporal mixing layer with particle dispersion显示文摘Ling W Chung J N Troutt T R 1998J Fluid Mech1998,358,:1
4Direct numerical simulation of a three-dimensional temporal mixing layer with particle dispersion 显示文摘Ling W Chung J N Troutt T R 1998Journal of Fluid Mechanics1998,358,:1
5Development of a mode of application of bioorganic fertilizer for improving the biocontrol efficacy to Fusarium wilt 显示文摘Ling N Xue C Huang Q W 2010Biocontro12010,55,:1
6Spatial and temporal characterization of phase fluctuations in non-Kolmogorov atmospheric turbulenc显示文摘RAO C JIANG W LING N 2000Journal of Modern Optics2000,47,:1
7Intemal Marketing and Customer Driven Wavefronts显示文摘Brooks R F I N Lings M A Botschen 1999The Service Industries Journal1999,19,4:1
8Urinary IL-18 and NGAL as early predictive biomarkers in contrast-induced nephropathy after coronary angiography显示文摘Ling W Zhaohui N Ben H 2008Nephron Clin Praet2008,108,3:1
9Visual feedback guided robotic cherry tomato harvesting显示文摘Kondo N Nishitsuji Y Ling P 1996Transactions of the ASAE1996,39,6:1
10A mutant Shiga-like toxin Ⅱ e bound to its receptor Gb3:structure of a group Ⅱ Shiga-like toxin with altered binding specificity显示文摘Ling H Pannu N S Boodhoo A 2000Structure Fold Des2000,158,3:1
11Development of a modeof application of bioorganic fertilizer for improving thebiocontrol efficacy to Fusarium显示文摘Ling N Xue C Huang Q W 2010BioControl2010,55,:1
12A Differential Evolution Algorithm with Self-adapting Strategy and Control Parameters显示文摘Pan Quanke Suganthan P N Wang Ling 2011Computers&Operations Research2011,38,1:1
13Identification and role of organic acids in watermelon root exudates for recruiting Paenibacillus polymyxa SQR-21 in the rhizosphere显示文摘Ling N Raza W Ma J H 2011Eur J Soil Biol2011,47,6:1
14Complementary DNA sequences of ovarian follicular fiu!d inhibin show precursor structure and ho- mology with trmisforming growth factor 显示文摘Mason AJ Hayflick JS Ling N 1985Nature1985,318,:1
15Internal marketing and customer drivenwave fronts显示文摘Brooks R F Lings L N Botsehen M A 1999Service Industries Journal1999,19,4:1
16Effects of temperature and chemical formulation on the acute toxicity of pentachlorophenol to Simocephalus vetulus (Schoedler, 1858) (Crustacea:Cladocera)显示文摘Willis K J N Ling M A Chapman 1995N Z J Mar Freshw Res1995,29,2:1
17A differential evolution algorithm with self-adapting strategy and control parameters显示文摘PAN Quan-ke SUGANTHAN P N WANG Ling 2011Computers & Operations Research2011,38,1:1
18Isolation and partial character- ization of a Mr 32,000 protein with inhibin activity from porcine follicular fluid显示文摘LING N YING S Y UENO N 1985PNAS1985,82,21:1
19Spatial and temporal char-acterization of phase fluctuations in non-Kolmogorov turbu- lence显示文摘C H RAO W H JIANG N LING 2000Journal of Modem Optics2000,47,6:1
20Contour based object detection using part bundles显示文摘Lu C E Adluru N Ling H B 2010Computer Vision and Image Understand- ing2010,114,7:1
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