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| 1 | The plant hormone zeatin riboside inhibits T lymphocyte activity via adenosine A2A receptor activation显示文摘细胞激动素是在植物生长和开发的多重方面起一个不可分的作用的植物荷尔蒙。然而,在哺乳动物的系统的细胞激动素的生物功能大部分是 uncharacterized。自然地发生的细胞激动素玉米素核糖甙最近被表明了激活2A受体,它是广泛地包括免疫系统房间由各种各样的房间类型表示了的哺乳动物的腺苷,与 A 的激活 2A在房间的规定起一个作用的 R 在天生、适应的免疫包含了。我们第一次证明玉米素核糖甙经由 A 调制哺乳动物的免疫系统活动 2AR 依赖的机制。明确地,玉米素核糖甙处理由 T 淋巴细胞导致周期的腺苷 monophosphate (营地)的生产并且由 CD3 +干扰素( IFN )的 CD4 + T 房间-γ, IL-2 ,肿瘤坏死因素( TNF )-α, IL-4 和 IL-13 ,并且由 CD3 + IFN-γ 的 CD8 + T 房间;, IL-2 和 TNF-α ;。另外,由激活的 T 淋巴细胞的 CD25, CD69 和 CD40L 的 upregulation 被玉米素核糖甙调制。玉米素核糖甙处理 potently 也禁止导致 thioglycollate 的腹白细胞增多。玉米素核糖甙的 immunomodulatory 活动被合作处理与选择 A 堵住 2A R 对手 ZM241385。这些数据建议那玉米素核糖甙作为一个哺乳动物的 immunomodulatory 代理人拥有治疗学的潜力。 | Courtney M Lappas | 2015 | Cellular & Molecular Immunology2015，12，1： | 3 |
| 2 | 急性阑尾炎的间隔平淡的阑尾切除术追随者保守人士处理: 它确实被需要显示文摘 Conservative management of acute appendicitis (AA) is gradually being adopted as a valuable therapeutic choice in the treatment of selected patients with AA. This approach is based on the results of many recent studies indicating that it is a valuable and effective alternative to routine emergency appendectomy. Existing data do not support routine interval appendectomy following successful conservative management of AA; indeed, the risk of recurrence is low. Moreover, recurrences usually exhibit a milder clinical course compared to the first episode of AA. The role of routine interval appendectomy is also questioned recently, even in patients with AA complicated by plastron or localized abscess formation. Surgical judgment is required to avoid misdiagnosis when selecting a conservative approach in patients with a presumed 'appendiceal' mass. | George H Sakorafas Dimitrios Sabanis Christos Lappas Aikaterini Mastoraki John Papanikolaou Charalambos Siristatidis Vasileios Smyrniotis | 2012 | World Journal of Gastrointestinal Surgery2012，4，4： | 3 |
| 3 | 先进的湿法成形非织造技术显示文摘湿法成形非织造产品现今越来越显现出其重要性。这种工艺需要将原材料打碎成纤维,浸没于水中,然后在斜网部成形。本文介绍了AndritzKfisters(安德里兹寇司德)公司neXformerwetlaid湿法成形机技术。安德里兹寇司德湿法成形生产线技术提供绝大部分应用领域的完整生产线方案,从浆料制备到neXformer湿法成形机到烘干、后整理和卷绕等。 | Loannis Lappas | 2009 | 纺织导报2009，，7： | 2 |
| 4 | Phospholipase A2 isozymes in pregnancy and parturition显示文摘 | Lappas M Rice GE | 2004 | Prostaglandins Leukot Essent Fatty Acids2004，70，2： | 1 |
| 5 | abdominal radiography findings in small -bowel obstruction: relevance to triage for additional diagnostic Imaging显示文摘 | Lappas JC Reyes BL Maglinte DD | 2001 | AJR Am J Roentgenol2001，176，1： | 1 |
| 6 | Preoperative detection of cervical lymph node metastases in papillary thyroid cancer: a surgical perspective显示文摘 | Sakorafas G H Christodoulou S Lappas C | 2009 | Onkologie2009，32，12： | 1 |
| 7 | Robust control moment gyro- scope steering logic with gimbal angle constraints 显示文摘 | LAPPAS V J WIE B | 2009 | Journal of guidance control and dynamic2009，32，5： | 1 |
| 8 | Calcium antagonists decrease plasma and tissue concentrations of TNF - α, interleukin-1β,and interleukin- 1αin a raouse model of endotoxin显示文摘 | Hotchkiss RS Osbme DF Lappas GD | 1996 | Shock1996，3，： | 1 |
| 9 | Biomass pyrolysis in a circulating fluid bed reactor for the production of fuels and chemicals 显示文摘 | LAPPAS A A SAMOLADA M C IATRIDIS D K | 2002 | Fuel2002，81，： | 1 |
| 10 | Attitude control systems for agile atatellites using control moment gyros 显示文摘 | LAPPAS V J STEYN W H UNDERWOOD C I | 2002 | Acta Astronautica2002，51，1： | 1 |
| 11 | In response to oxidative stress, the expression of inflammatory cytokines and antioxidant enzymes are impaired in placenta, but not adipose tissue, of women with gestational diabetes显示文摘 | Lappas M Mittion A Permezel M | 2010 | Endocrinology2010，204，1： | 1 |
| 12 | In response to oxidative stress,the expression of inflammatory cytokines and antioxidant enzymes are impaired in placenta,but not adipose tissue,of women with gestational diabetes显示文摘 | Lappas M Mitton A Permezel M | 2010 | J Endocrinol2010，204，1： | 1 |
| 13 | Independent importance of psychosocial factors for prognosis after myocardial infarction显示文摘 | Welin C Lappas G Wilhelmsen L | 2000 | J Intern Med2000，247，6： | 1 |
| 14 | Biomass pyrolysis in a circulating fluid bed reactor for the production of fuels and chemicals显示文摘 | LAPPAS A A SAMOLADA M C IATRIDIS D K | 2002 | Fuel2002，81，16： | 1 |
| 15 | Effect of metals poisoning on FCC products yields: studies in an FCC short contact timepilot plant unit显示文摘 | Lappas A A Nalbandian L Iatridis D K | 2001 | Catalysis Today2001，65，24： | 1 |
| 16 | Investigationof K-promoted Cu-Zn-Al, Cu-X-Al and Cu-Zn-X (X= Cr,Mn) catalysts for carbon monoxide hydrogenation to higheralcohols显示文摘 | Heracleous E Liakakou E Lappas A | 2013 | Appl Catal A2013，455，： | 1 |
| 17 | Abdominal radiography findings in small-bowel obstruction显示文摘 | Lappas JC Reyes BL Maglinte DDT | 2001 | AIR2001，176，1： | 1 |
| 18 | Abdominal radiography findings in small bowel obstruction:relevance to triage for additional diagnostic imaging显示文摘 | REYES B L MAGLINTE D D | 2001 | AJR2001，176，： | 1 |
| 19 | Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factorkappa B,peroxisomal proliferator-activated receptor-and extracellularlyregulated kinase1/2显示文摘 | Permezel M Rice GE | 2005 | Endocrinology2005，146，8： | 1 |
| 20 | Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via NF-κB,PPAR-γ and ERK 1/2显示文摘 | Lappas M Permezel M Rice GE | 2005 | Endocrinology2005，146，8： | 1 |
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