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| 1 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 2 | HIGH ACCURACY ANALYSIS OF THE WILSON ELEMENT显示文摘In this paper, the Wilson nonconforming finite element is considered for solvinga class of second-order elliptic boundary value problems. Based on an asymptoticerror expansion for the Wilson finite element, the global superconvergences, thelocal superconvergences and the defect correction schemes are presented. | Luo, P Lin, Q | 1999 | Journal of Computational Mathematics1999，17，2： | 11 |
| 3 | Melatonin treatment induces chilling tolerance by regulating the contents of polyamine,γ-aminobutyric acid,and proline in cucumber fruit显示文摘The mechanism of melatonin(MT)induced chilling tolerance in harvested cucumber fruit was investigated at commercial maturity.In this study,cucumber fruits were treated with 100μmol L^(-1) MT at 4℃ and 90% relative humidity for 15 d of storage.In comparison with the control,cucumber treatment with MT resulted in reduced chilling injury(CI),decreased electrolyte leakage and enhanced firmness.The fruits treated with MT showed higher chlorophyll contents in storage conditions with suppressed chlorophyllase enzyme activity.MT treatment increased arginine decarboxylase(ADC)and ornithine decarboxylase(ODC)enzyme activities.Moreover,enhanced expression of the Cucumis sativus ADC(CsADC)and C.sativus ODC(CsODC)genes resulted in the accumulation of polyamine contents.Similarly,proline levels exhibited higher levels among treated fruits.Meanwhile,the proline synthesizing enzymes △1-pyrroline-5-carboxylate syntheses(P5CS)and ornithine aminotransferase(OAT)were significantly increased,while a catabolic enzyme of proline dehydrogenase(PDH)activity was inhibited by treatment.In addition,MT induced expression of C.sativus OAT(CsOAT)and C.sativus P5CS(CsP5CS)genes.Cucumber fruits treated with MT also exhibited higher γ-aminobutyric acid(GABA)content by enhanced GABA transaminase(GABA-T)and glutamate decarboxylase(GAD)enzyme activities and a higher C.sativus GAD(CsGAD)gene expression.To sum up,the results show that MT treatment enhanced chilling tolerance,which was associated with the regulation of polyamines,as well as proline and γ-aminobutyric acid. | Miilion P MADEBO LUO Si-ming WANG Li ZHENG Yong-hua JIN Peng | 2021 | Journal of Integrative Agriculture2021，20，11： | 6 |
| 4 | Management Strategies and Research Orientations of Forest Diseases and Pests in China显示文摘Forest diseases and pests are perceived as a growing hazard to China economy. It is a common conclusion that the actualities of forest pests in china are no effective measures to the old important pests, some secondary pests are ascending to chief pests, increasing devastation from exotic pests, frequent ecological pest eruption induced by environmental detriment and host-leading diseases to threaten the 'Western Development Project 'in China, which is the most important economical strategy to China; th... | ZHANG Xingyao LIANG Jun LU Quan YAN Donghui LUO Youqing XU Zhichun WEN Junbao1. Research Institute of Forest Ecology. Environment and Protection. Chinese Academy of Forestry. Beijing, 100091. P R China:2. College of Biological Sciences and Technology. Beiiine Forestry University. Beiiine. 100083. P R China | 2002 | Chinese Forestry Science and Technology2002，1，2： | 4 |
| 5 | 油菜远缘杂交育种中器官离体培养的应用显示文摘 | 向平 Luo,P | 2001 | 国外作物育种2001，20，2： | 3 |
| 6 | 油炸食品与心血管病风险和全因死亡率的关系:观察性研究的荟萃分析显示文摘研究者进行了一项荟萃分析,包括剂量反应分析,以定量确定油炸食品摄入与普通成年人群心血管病风险和全因死亡率之间的关系。方法:研究者在PubMed、EMBASE和Web of Science上检索2020年4月11日之前的所有文章。应用随机效应模型估计总的相对危险度(relative risks,RR)和95%CI。结果:与最低油炸食品摄入量相比,最高摄入量者主要心血管事件的总RR(95%CI)=1.28(1.15~1.43),n=17,I^(2)=82.0%,其中前瞻性研究:1.24(1.12~1.38),n=13,I^(2)=75.7%. | 刘青(译) 练桂丽(审校) Qin P Zhang M Han M Liu D Luo X Xu L Zeng Y Chen Q Wang T Chen X Zhou Q Li Q Qie R Wu X Li Y Zhang Y Wu Y Hu D Hu F | 2021 | 中华高血压杂志2021，29，2： | 3 |
| 7 | 老年人为何易发皮肤瘙痒:机械敏感离子通道Piezo2-Merkel细胞调控触觉到痒觉的转化显示文摘躯体感觉系统负责传递从轻触、疼痛和瘙痒的多种信号。触觉对空间意识和交流至关重要。然而,在疾病状态下,无害的机械刺激可引发诸如机械性瘙痒(触诱发痒)等病理性感觉。目前控制这种转化的分子细胞机制仍属未知。研究者发现,在小鼠中衰老和干皮病诱发的机械性瘙痒与Merkel细胞(皮肤中的触觉感受器)的丧失有关。靶向遗传性删除皮肤中Merkel细胞或相关的机械敏感离子通道Piezo2足以产生机械性瘙痒。化学遗传学激活残存的Merkel细胞可治疗干皮病诱导的机械性瘙痒。该研究揭示了皮肤触觉感受器先前未知的功能,并提供了机械性瘙痒发生发展的新见解。 | Feng J Luo J Yang P 王志红(译) 胡月(译) 刘通(校) | 2019 | 中国疼痛医学杂志2019，25，5： | 3 |
| 8 | Optical secure communications with chaotic erbium-doped fiber lasers 显示文摘 | Luo L G Chu P L | 1998 | J Opt Soc Am B1998，15，1： | 2 |
| 9 | 纳米光子结构软膜紫外光固化纳米压印(英文)显示文摘紫外光固化纳米压印是实现纳米结构批量复制的一种新技术.其特点是低成本和高分辨,而且可以达到极高的套刻精度.为了得到大面积图案的均匀复制,可用聚二甲基硅氧烷(PDMS)制备透光的压印软模板.其母版图案可由高分辨率电子束曝光和反应离子刻蚀的方法在硅片基底上获得,然后用浇注的方法将图案转移到PDMS上.本实验特别发展了紫外光固化纳米压印适用于软膜压印的双层膜图型转移技术.该双层膜由廉价的光胶和聚甲基丙烯酸甲脂(PMMA)构成.对光胶层的压印可用普通的光学曝光仪实现.然后再将图案用反应离子刻蚀的方法转移到PMMA层中.为了证明方案的可行性,在两种不同材料的半导体基片上压印了三角晶格的光子晶体和准晶结构的图案,并用剥离的方法将它们转移到金属薄膜上,最后成功地进行了硅片刻蚀实验.相信这一纳米制做方法对大面积纳米光子结构和光学集成芯片的制造是普遍适用的. | SHI J WANG Z M BAO K PEROZ C BELOTTI M XU L P LUO C X SUN M H ZHANG B JI H OUYANG Q CHEN Y | 2006 | 纳米技术与精密工程2006，4，3： | 2 |
| 10 | Association between high-sensitivity cardiac troponin T and N-terminal pro-brain natriuretic peptide in a community based population显示文摘 | Xu RY Ye P Luo LM Sheng L Wu HM Xiao WK Zheng J Wang F Xiao TH | 2014 | Chinese Medical Journal2014，，4： | 2 |
| 11 | Exogenous cytokinin application to Actinidia chinensis var. deliciosa ‘Hayward’ fruit promotes fruit expansion through water uptake显示文摘Exogenous application of a cytokinin-like compound forchlorfenuron(CPPU)can promote fruit growth,although often at the expense of dry matter(DM),an important indicator of fruit quality.Actinidia chinensis var.deliciosa‘Hayward’fruit are very responsive to CPPU treatments,but the mechanism underlying the significant fruit weight increase and associated decrease in DM is unclear.In this study,we hypothesised that CPPU-enhanced growth increases fruit carbohydrate demand,but limited carbohydrate supply resulted in decreased fruit DM.During fruit development,CPPU effects on physical parameters,metabolites,osmotic pressure and transcriptional changes were assessed under conditions of both standard and a high carbohydrate supply.We showed that CPPU increased fruit fresh weight but the dramatic DM decrease was not carbohydrate limited.Enhanced glucose and fructose concentrations contributed to an increase in soluble carbohydrate osmotic pressure,which was correlated with increased water accumulation in CPPU-treated fruit and up-regulation of water channel aquaporin gene PIP2.4 at 49 days after anthesis.Transcipt analysis suggested that the molecular mechanism contributing to increased glucose and fructose concentrations was altered by carbohydrate supply.At standard carbohydrate supply,the early glucose increase in CPPU fruit was associated with reduced starch synthesis and increased starch degradation.When carbohydrate supply was high,the early glucose increase in CPPU fruit was associated with a general decrease in starch synthesis but up-regulation of vacuolar invertase and fructokinase genes.We conclude that CPPU affected fruit expansion by increasing the osmotically-driven water uptake and its effect was not carbohydrate supply-limited. | Simona Nardozza Helen L Boldingh Mark W Wohlers Andrew P Gleave Zhiwei Luo Guglielmo Costa Elspeth A MacRae Michael J Clearwater Annette C Richardson | 2017 | Horticulture Research2017，4，1： | 2 |
| 12 | A review on blind detection for image steganography显示文摘 | LUO X Y WANG D S WANG P | 2008 | Signal Processing2008，88，9： | 1 |
| 13 | Image enhancement and minutiae matching in fingerprint verification显示文摘 | He Y L Tian J Luo X P | 2003 | Pattem Recognition Letters2003，24，910： | 1 |
| 14 | Mechanical efficacy of vertebroplasty: influence of cement type, BMD, fracture severity, and disc degeneration显示文摘 | Luo J Skrzypiec DM Pollintine P | 2007 | Bone2007，40，4： | 1 |
| 15 | Artificial lotus leaf by nanocasting显示文摘 | Sun M H Luo C X Xu L P | 2005 | Langmuir2005，21，19： | 1 |
| 16 | Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein显示文摘 | Ducy P Mckee MD | 1997 | Nature1997，386，： | 1 |
| 17 | 显示文摘 | Luo Q Hovsepian P E | 2006 | Thin Solid Films2006，497，： | 1 |
| 18 | Theory of the lattice Boltzmann method: acoustic and thermal properties in two and three dimensions显示文摘 | Lallemand P LUO Lishi | 2003 | Physical Review E2003，68，03： | 1 |
| 19 | Adiponec- tin multimeric complexes and the metabolic syndrome trait cluster 显示文摘 | Lara- Castro C Luo N Wallace P | 2006 | Diabetes2006，55，1： | 1 |
| 20 | Effects of Zn-complexes on zinc uptake by wheat(Triticum aestivttm) roots:A comprehensive consideration of physical, chemical and biological processes on bio-uptake显示文摘 | Wang P Zhou D M Luo X S | 2009 | Plant Soil2009，316，： | 1 |
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