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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Hepatic ischemic preconditioning increases portal vein flow in experimental liver ischemia reperfusion injury显示文摘BACKGROUND: Ischemic preconditioning(IPC) has been shown to decrease liver injury and to increase hepatic microvascular perfusion after liver ischemia reperfusion. This study aimed to evaluate the effects of IPC on hemodynamics of the portal venous system. METHODS: Thirty-two rats were randomized into two groups: IPC group and control group. The rats of the IPC group underwent IPC by 10 minutes of liver ischemia followed by 10 minutes of reperfusion before liver ischemia, and the rats of the control group were subjected to 60 minutes of partial liver ischemia. Non-ischemic lobes were resected immediately after reperfusion. The animals were studied at 4 hours and 12 hours after reperfusion. Mean arterial pressure, heart rate, portal vein flow and pressure were analyzed. Blood was collected for the determination of the levels of aspartate aminotransferase, alanine aminotransferase, calcium, lactate, pH, bicarbonate, and base excess. RESULTS: IPC increased the mean portal vein flow at 4 hours and 12 hours after reperfusion. IPC recovered 78% of the meanportal vein flow at 12 hours after reperfusion. IPC decreased the levels of aspartate aminotransferase, alanine aminotransferase and lactate, and increased the levels of ionized calcium, bicarbonate and base excess at 12 hours after reperfusion. CONCLUSIONS: This study demonstrated that IPC increases portal vein flow and enhances hepatoprotective effects in liver ischemia reperfusion. The better recovery of portal vein flow after IPC may be correlated with the lower levels of transaminases and with the better metabolic profile. | Estela RR Figueira Joel A Rocha-Filho Mauro Nakatani Marcelo FS Buto Eduardo R Tatebe Vitor O Andre Ivan Cecconello Luiz AC D'Albuquerque | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，1： | 6 |
| 3 | Accelerating admixtures for shotcrete显示文摘 | LUIZ R P J | 1998 | Cement and Concrete Composites1998，20，： | 1 |
| 4 | Biotechnological applications of genetically modified Bacillus subtilis strains in the development of vaccines targeting different Escherichia coli pathotypes 显示文摘 | Luiz W Paccez J Ferreira R | 2009 | New Biotechnology2009，25，1： | 1 |
| 5 | A mult-objective approach to the short-term scheduling of a hydroelectric power system显示文摘 | Christiano L Luiz R Ferreira M | 1995 | IEEE Trans on PowerDelivery1995，10，4： | 1 |
| 6 | Activated carbon liron oxide magnetic composites for the adsorption of contaminants in water 显示文摘 | Oliveira Luiz C A Rios Rachel V R A Jos D | 2002 | Carbon2002，40，： | 1 |
| 7 | Clay-iron oxide magnetic composites for the adsorption of contaminants in water 显示文摘 | Luiz C A Oliveira Rachel V R A Rios Jose D Fabris | 2003 | Applied Clay Science2003，22，： | 1 |
| 8 | A multi-objective approach to the short-term scheduling of a hydroelectric power system 显示文摘 | Christiano L Luiz R | 1995 | IEEE Trans on PAS1995，10，4： | 1 |
| 9 | CTdatabase: aknowledge-base of high-throughput and curated data oncancer-testis antigens显示文摘 | Luiz G A Noboru J S Alice R O | | Nucleic Acids R e s0，37，： | 1 |
| 10 | Foreign Direct Investment in Developing Countries and Growth: A Selective Survey显示文摘 | DE MELLO Jr | 1997 | The Journal of Development Studies1997，34，1： | 1 |
| 11 | Joint dynamics modeling and parameter identification for space robot applications 显示文摘 | Adenilson R da Silva Luiz C | 2007 | Mathematical Problems in Engineering2007，1，10： | 1 |
| 12 | Methods for yeast characterization from industrial products 显示文摘 | LUIZ H G KEILA M R Duarte J L A etal | 2000 | Food Microbiol2000，17，： | 1 |
| 13 | Thermal dynamic analysis of a coke dry quenching unit 显示文摘 | Marcelo R E Luiz F M | 2000 | Energy Conversion & Management2000，41，： | 1 |
| 14 | Rapid Chloride Permeability Test on Blended Cement and Other Concretes:Correlation between Charge Initial Current and Conductivity显示文摘 | Rolf Feldman Luiz R Prudencio Jr | 1999 | Construction and Building Materials1999，13，： | 1 |
| 15 | Mechanism of anticlasogenicity of Agaricus blazei murill mushroom organic extracts in wild type CHO(K1) and repair deficient (xrs5) cells by chromosome aberration and sister chromatid exchange assays显示文摘 | Jordao B Q da Eira A F Ribeiro L R Mantovani M S | 2003 | Mutation Research2003，528，1： | 1 |
| 16 | Pleural fluid ADA, IgA-ELISA and PCR sensitivities for the diag- nosis of pleural tuberculosis 显示文摘 | TRAJMAN A KAISERMANN C LUIZ R R | 2007 | Scand J Clin Lab Invest2007，67，8： | 1 |
| 17 | Is visual scanning better than mental practice in hemispatial neglect? Re- suits from a pilot study 显示文摘 | FERREIRA H P LEITE LOPES M A LUIZ R R | 2011 | Top Stroke Rehabil2011，18，2： | 1 |
| 18 | Activated carbon/iron oxide magnetic composites for the adsorption of contaminats in water显示文摘 | Rios Rachel V R A Fabris José D | 2002 | Carbon2002，40，12： | 1 |
| 19 | Domestic Effluent Treatment Through Integrated System of Septic Tank and Root Zone显示文摘 | RE JANE H R PABLO H Sezerino | 1999 | Water Science and Technology1999，40，3： | 1 |
| 20 | Fortification of flours with folic acid reduces homocysteine levels in Brazilian women显示文摘 | Scorsatto M Uehara S K Luiz R R | 2011 | Nutrition Research2011，31，12： | 1 |
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