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| 1 | Heat Transfer in Steelmaking Ladle显示文摘The heat transfer in a steelmaking ladle was studied. The evaluation of heat transfer of the steel was performed by measuring steel temperature in points including all refining steel process. In the ladle, the temperatures in the refractories and the shell were also measured. To evaluate the thermal profile between the hot and cold faces of the ladle in the slag line position, an experiment which shows the importance of thermal contact resistance was carried out. Higher heat losses in the tapping and the vacuum were verified. The temperature measurements of the ladle indicate distinct thermal profiles in each stage of steel refining. Moreover, as each stage of the process depends on the previous one, the complexity of the ladle thermal control is incremental. So a complete model of heat losses in the ladle is complex. | André Zimmer lvaro Niedersberg Correia Lima Rafael Mello Trommer Saulo Roca Bragana Carlos Pérez Bergmann | 2008 | Journal of Iron and Steel Research(International)2008，15，3： | 4 |
| 2 | Biological therapy in inflammatory bowel diseases:Access in Central and Eastern Europe显示文摘Biological drugs opened up new horizons in the management of inflammatory bowel diseases(IBD).This study focuses on access to biological therapy in IBD patients across 9 selected Central and Eastern European(CEE)countries,namely Bulgaria,the Czech Republic,Estonia,Hungary,Latvia,Lithuania,Poland,Romania and Slovakia.Literature data on the epidemiology and disease burden of IBD in CEE countries was systematically reviewed.Moreover,we provide an estimation on prevalence of IBD as well as biological treatment rates.In all countries with the exception of Romania,lower biological treatment rates were observed in ulcerative colitis(UC)compared to Crohn’s disease despite the higher prevalence of UC.Great heterogeneity(up to 96-fold)was found in access to biologicals across the CEE countries.Poland,Bulgaria,Romania and the Baltic States are lagging behind Hungary,Slovakia and the Czech Republic in their access to biologicals.Variations of reimbursement policy may be one of the factors explaining the differences to a certain extent in Bulgaria,Latvia,Lithuania,and Poland,but association with other possible determinants(differences in prevalence and incidence,price of biologicals,total expenditure on health,geographical access,and cost-effectiveness results)was not proven.We assume,nevertheless,that healthdeterioration linked to IBD might be valued differently against other systemic inflammatory conditions in distinct countries and which may contribute to the immense diversity in the utilization of biological drugs for IBD.In conclusion,access to biologicals varies widely among CEE countries and this difference cannot be explained by epidemiological factors,drug prices or total health expenditure.Changes in reimbursement policy could contribute to better access to biologicals in some countries. | Fanni Rencz Márta Péntek Martin Bortlik Edyta Zagorowicz Tibor Hlavaty Andrzej Sliwczyński Mihai M Diculescu Limas Kupcinskas Krisztina B Gecse László Gulácsi Peter L Lakatos | 2015 | World Journal of Gastroenterology2015，21，6： | 4 |
| 3 | Brainstem gliomas--retrospective analysis of 86 patients显示文摘 | Ueoka DI Nogueira J Campos JC Maranhao Filho P Ferman S Lima MA | 2009 | 中国神经肿瘤杂志2009，7，3： | 3 |
| 4 | Ly49 receptors activate angiogenic mouse DBA+ uterine natural killer cells显示文摘 | Patricia DA Lima Megan M Tu Mir Munir A Rahim Annie R Peng B Anne Croy Andrew P Makrigiannis | 2014 | Cellular & Molecular Immunology2014，11，5： | 3 |
| 5 | Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats显示文摘AIM To evaluate the sex-specific effects of a hydroalcoholic extract from Eugenia punicifolia(HEEP) leaves on gastric ulcer healing.METHODS In this rat study involving males, intact(cycling) females, and ovariectomized females, gastric ulcers were induced using acetic acid. A vehicle, lansoprazole, or HEEP was administered for 14 d after ulcer induction. Body weight was monitored throughout the treatment period. At the end of treatment, the rats were euthanized and the following in vivo and in vitro investigations were performed: macroscopic examination of the lesion area and organ weights, biochemical analysis, zymography, and evaluation of protein expression levels. Additionally, the concentration-dependent effect of HEEP was evaluated in terms of subacute toxicity and cytotoxicity.RESULTS Compared to the vehicle, HEEP demonstrated a great healing capacity by substantially reducing the ulcerative lesion area in males(52.44%), intact females(85.22%), and ovariectomized females(65.47%), confirming that HEEP accelerates the healing of acetic acidinduced gastric lesions and suggesting that this effect is modulated by female sex hormones. The antiulcer effect of HEEP was mediated by prostaglandin E2 only in male rats. Overall, the beneficial effect of HEEP was the highest in intact females. Notably, HEEP promoted the expression of vascular endothelial growth factor(intact vs ovariectomized females) and decreased the expression of Caspase-8 and Bcl-2(intact female vs male or ovariectomized female). Additionally, HEEP enhanced fibroblast proliferation and migration into a wounded area in vitro, confirming its healing effect. Finally, no sign of subacute toxicity or cytotoxicity of HEEP was observed.CONCLUSION In gastric ulcers, HEEP-induced healing(modulated by female sex hormones; in males, mediated by prostaglandin) involves extracellular matrix remodeling, with gastric mucosa cell proliferation and migration. | Larissa Lucena Périco Vinícius Peixoto Rodrigues Rie Ohara Gabriela Bueno Vania Vasti Alfieri Nunes Raquel Cássia dos Santos Ana Carolina Lima Camargo Luis Antuio Justulin Joior Sérgio Faloni de Andrade Viviane Miranda Bispo Steimbach Luísa Mota da Silva Lúcia Regina Machado da Rocha Wagner Vilegas Catarina dos Santos Clélia Akiko Hiruma-Lima | 2018 | World Journal of Gastroenterology2018，24，38： | 3 |
| 6 | Acute fatty liver of pregnancy associated with severe acute pancreatitis:A case report显示文摘Acute fatty liver of pregnancy is a rare disease that affects women in the third trimester of pregnancy. Although infrequent, the disease can cause maternal mortality. The diagnosis is not always clear until the pregnancy is terminated, and significant complications, such as acute pancreatitis, can occur. Pancreatic involvement typically only occurs in severe cases after the development of hepatic and renal impairment. To date, little knowledge is available regarding how the disease causes pancreatitis. Treatment involves supportive measures and pregnancy interruption. In this report, we describe a case of a previously healthy 26-year-old woman at a gestational age of 27 wk and 6 d who was admitted with severe abdominal pain and vomiting. This case illustrates the clinical and laboratory overlap between acute fatty liver of pregnancy and pancreatitis, highlighting the difficulties in differentiating each disease. Furthermore, the hypothesis for this overlapping is presented, and the therapeutic options are discussed. | Cássio Vieira de Oliveira Alecsro Moreira Julio P Baima Leticia de C Franzoni Talles B Lima Fabio da S Yamashiro Kunie Yabuki Rabelo Coelho Ligia Y Sassaki Carlos Antonio Caramori Ferno G Romeiro Giovanni F Silva | 2014 | World Journal of Hepatology2014，6，7： | 3 |
| 7 | Monitoring urea levels during haemodialysis with a pulsed-flow chemiluminescence analyser显示文摘 | Lewisa S W Francisa P S Lima K F | 2002 | Anal Chim Acta2002，461，1： | 2 |
| 8 | 显示文摘 | Lima M D de Andrade M J Bergmann C P | 2008 | J Mater Chem2008，18，： | 1 |
| 9 | Increased inflammatory response in patients with dilated cardiomyopathy is associated with dyslipidemia:Effects of statin therapy显示文摘 | Iakovis P Anyfantakis ZA Limas C | 2011 | Angiology2011，62，1： | 1 |
| 10 | One-step RT-PCR protocols improve the rate of dengue diagnosis com- pared to two-step RT-PCR approaches显示文摘 | De Paula S O D Lima C D M Torres M P | 2004 | J Clin Virol2004，30，： | 1 |
| 11 | Simplified modeling of a DFIG for transient studies in wind power applica- tions显示文摘 | LUNA A LIMA F K RODRIGUEZ D SANTOS P | 2011 | IEEE Transactions on Industrial Electronics2011，58，1： | 1 |
| 12 | Adsorption modeling of Cr,Cd and Cu on activa- ted carbon of different origins by using fractional factorial design 显示文摘 | De Lima L S Araujo M D M QuinOia S P | 2011 | Chemical Engineering Jour- nal2011，166，3： | 1 |
| 13 | Rotor voltage dynamics in the doubly fed induction generator during grid faults显示文摘 | Lima F K Luna A Rodriguez P A | 2010 | IEEE Transactions on Power Electronics2010，25，1： | 1 |
| 14 | A Mathematical model for evaluating the effect of wind on downward-spraying rainfall simulators显示文摘 | De Lima J L M P Torfs P J J F Singh V P | 2002 | Catena2002，46，4： | 1 |
| 15 | Stomatal responses of Eucalyptus species to elevated CO2 concentration and drought stress显示文摘 | Jarvis P Rhizopoulou S | 2003 | Scientia Agricola2003，60，2： | 1 |
| 16 | Efficacy of low--level laser therapy and aluminum hydroxide in pa- tients with chemotherapy and radiotherapy-induced oral mucositis显示文摘 | Lima A G Antequera R Peres M P | 2010 | Braz Dent J2010，21，3： | 1 |
| 17 | A Fuzzy Modcl for Function Point Analysis to Development and Enhancement Project Assessments显示文摘 | de Souza Lima Júnior O Farias P P M Belchior AD | 1990 | CLEI Electronic Journal1990，5，2： | 1 |
| 18 | Rotor voltage dynamic in the doubly fed induction generator during grid faults 显示文摘 | Lima F K A Luna A Rodriguez P | 2010 | IEEE Trans on Power Electronics2010，25，1： | 1 |
| 19 | Prognostic factors and out- come for nasopharyngeal carcinoma 显示文摘 | Farias T P Dias F L Lima R A | 2003 | Arch Otolalyngol Head Neek Surg2003，129，7： | 1 |
| 20 | Boron nanop article-rich fuels for gas generators and propellants显示文摘 | Lima RJ P DuboisC Mader O Stowe R | 2010 | Interna tional Journal of Energetic Materials and Chemical Propulsion2010，9，5： | 1 |
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