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| 1 | Phase Evolution during the Sintering of Submicron Ti(C,N)-Based Cermets显示文摘The submicron powder mixtures of TiC-TiN-WC-Mo-C-Ni sintered at 1400℃ or below in vacuum were studied by X-ray diffration (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) analyses. The results showed that Mo2C fOrmed at 800℃ or below. Both WC and Mo2C disappeared at 1200 ℃, and TiN disappeared at 1250℃. In addihon, the variahons of lanice constans of the htanium carbonitride and nickel binder phase with sintering temperature were experimentally obtained, and the reason was analyzed. | Li, CH Xiong, WH Yu, LX | 2001 | Rare Metals2001，20，4： | 4 |
| 2 | Risk factors and natural history of breast cancer in younger Chinese women显示文摘AIM: To investigate the age differences in the risk factors, clinicopathological characteristics and patterns of treatment of female breast cancer patients. METHODS: Seven thousand one hundred and fiftytwo women with primary breast cancer from the Hong Kong Breast Cancer Registry were recruited after receiving patients' consent, they were asked to complete standardized questionnaires which captured their sociodemographic characteristics and risk factors associated with breast cancer development. Among them, clinicopathological data and patterns of treatment were further collected from medical records of 5523 patients with invasive breast cancers. Patients were divided into two groups according to the age at diagnosis: younger(< 40 years old) vs older patients(≥ 40 years old) for subsequent analyses.RESULTS: Analysis on the sociodemographic characteristics and exposure to risk factors were performed on 7152 women with primary breast cancer and the results revealed that younger patients were more likely to have unhealthy lifestyles; these include a lack of exercise(85.4% vs 73.2%, P < 0.001), having high stress in life(46.1% vs 35.5%, P < 0.001), having dairy/meat-rich diets(20.2% vs 12.9%, P < 0.001),having alcohol drinking habit(7.7% vs 5.2%, P = 0.002). Younger patients were also more likely to have hormone-related risk factors including nulliparity(43.3% vs 17.8%, P < 0.001) and an early age at menarche(20.7% vs 13.2%, P < 0.001). Analyses on clinicopathological characteristics and patterns of treatment were performed on 5523 women diagnosed with invasive breast cancer. The invasive tumours in younger patients showed more aggressive pathological features such as having a higher percentage of grade 3 histology(45.7% vs 36.5%, P < 0.001), having a higher proportion of tumours with lymphovascular invasion(39.6% vs 33.2%, P = 0.003), and having multifocal disease(15.7% vs 10.3%, P < 0.001); they received different patterns of treatment than their older counterparts.CONCLUSION: Younger patients in Hong Kong are more likely to encounter risk factors associated with breast cancer development and have more aggressive tumours than their older counterparts. | Winnie Yeo Hang-Mei Lee Amy Chan Emily YY Chan Miranda CM Chan Keeng-Wai Chan Sharon WW Chan Foon-Yiu Cheung Polly SY Cheung Peter HK Choi Josette SY Chor William WL Foo Wing-Hong Kwan Stephen CK Law Lawrence PK Li Janice WH Tsang Yuk Tung Lorna LS Wong Ting-Ting Wong Chun-Chung Yau Tsz-Kok Yau Benny CY Zee | 2014 | World Journal of Clinical Oncology2014，5，5： | 4 |
| 3 | Slower cycling of nestin-positive cells in neurosphere culture显示文摘 | Ma BF Liu XM Xie XM Zhang AX Zhang JQ Yu WH Zhang XM Li SN Lahn BT Xiang AP | 2006 | 中国生物学文摘2006，20，5： | 4 |
| 4 | Blockade of the swelling-induced chloride current attenuates the mouse neonatal hypoxic-ischemic brain injury in vivo显示文摘胀大导致 Cl 电流的激活(我 Cl,胀大 ) 在新生的组织缺氧局部缺血期间(嗨) 可以导致大脑损坏。Hypoxic-ischemic 大脑损害在出生不满一月的婴儿以及尖锐死亡引起长期的神经病学的病态。在这研究,我们调查了角色我 Cl,胀大在用选择 blocker 的 hypoxic-ischemic 大脑损害的 , 4-(2-butyl-6,7-dichloro-2-cyclopentylindan-1-on-5-yl ) oxybutyric 酸(DCPIB ) 。在主要有教养的外皮的神经原, 30% 张力减退的答案的灌注激活我 Cl,胀大是的 , 完全由 DCPIB (10 mol/L ) 的申请堵住了。角色我 Cl,胀大在在 vivo 的新生的 hypoxic-ischemic 大脑损害的 在一个修改新生的 hypoxic-ischemic 大脑损害模型被评估。在收到 ischemic 侮辱前,老鼠小狗与 DCPIB 被注射(10 mg/kg, ip ) 。我们发现有 DCPIB 的那个预告的处理显著地减少了用 TTC 染色, Nissl 染色和整个大脑成像估计的大脑损坏,并且改进了在 neurobehavioural 测试评估的感觉运动、门厅的恢复结果(即趋地性 reex,和峡谷回避 reex ) 。这些结果证明 DCPIB 在新生的 hypoxic-ischemic 大脑损害上有 neuroprotective 效果,并且 I Cl,胀大 可以为 hypoxic-ischemic encephalopathy 的处理用作一个治疗学的目标。 | Raymond WONG Ahmed ABUSSAUD Joseph WH LEUNG Bao-feng XU Fei-ya LI Sammen HUANG Nai-hong CHEN Guan-lei WANG Zhong-ping FENG Hong-shuo SUN | 2018 | Acta Pharmacologica Sinica2018，39，5： | 3 |
| 5 | Changes in soil microbial community associated with invasion of the exotic weed, Mikania micrantha HBK显示文摘 | Li WH Zhang CB Jiang HB Xin GR Yang ZY | 2007 | 中国生物学文摘2007，21，6： | 2 |
| 6 | Treatment of Helicobactor pylori infection:analysis of Chinese clinical trials显示文摘INTRODUCTION E radication of Helicobacter pylori(Hp)infection isgenerally not easy.Various clinical regimens havebeen recommended in the literature.With theexperience from the other countries and the practicein China,Chinese doctors have tried manyregimens.In this study,we collected and pooled thedata from Chinese literature to evaluate the effectof different regimens in Chinese patients infectedwith Hp. | Li YY Sha WH | 2000 | World Journal of Gastroenterology2000，6，3： | 2 |
| 7 | Mathematical model for study genetic variation in terms of restriction endonucleases 显示文摘 | Nei M Li WH | 1979 | Proc Natl Acad Sci USA1979，76，： | 2 |
| 8 | Low birth weight is associated with components of the metabolic syndrome 显示文摘 | Xiao X Zhang ZX Li WH | 2010 | Metabolism2010，59，： | 1 |
| 9 | Human polymorphism at microRNAs and microRNA target sites显示文摘 | Saunders MA Liang H Li WH | | 0，，： | 1 |
| 10 | Deep tiny flow voids along middle cerebral artery atherosclerotic occlusions a high-resolution MR imaging study显示文摘 | Xu WH Li ML Niu JW | 2014 | J Neurol Sci2014，339，： | 1 |
| 11 | Relationship between autoantibody clustering and clinical subsets in SLE: clus- ter and ssociation analyses in Hong Kong Chinese 显示文摘 | Li PH Wong WH Lee TL | 2013 | Rheumatology (Oxford)2013，52，2： | 1 |
| 12 | Neuroendoerine differentiation in 32 cases of cocalled sclerosing hemangioma of the lung: identified by immunohistochemical and ultrastrustructural study 显示文摘 | Xu HM Li WH Hou N | 1997 | Am J Surg Pathol1997，21，9： | 1 |
| 13 | Luminal thrombosis in middle cerebral artery occlusions: a high-resolution MRI study显示文摘 | Xu WH Li ML Niu JW | 2014 | Ann Transl Med2014，2，： | 1 |
| 14 | Role of Slit2/Robol in trophoblast invasion and vascular remodeling during ectopic tubal pregnancy 显示文摘 | Li P Peng H Lu WH | 2015 | Placenta2015，36，10： | 1 |
| 15 | ET-1 activates Ca^2+ sparks in PASMC :local Ca^2+ signaling between inmitol trisphosphate and ryanodine receptors显示文摘 | Zhang WM Li WH Yip KP | 2003 | Am J Physiol Lung Cell Mol Physiol2003，285，3： | 1 |
| 16 | The binding of Qinghaosu(Artemisinine) and itsderivatives to plasma protein显示文摘 | Li WH Shu HL Xu GY | 1982 | Acta Pharma Sin1982，17，： | 1 |
| 17 | Impact of anemia on con- trast-induced nephropathy (CIN) in patients undergoing percutaneous coronary interventions显示文摘 | Li WH Li DY Han F etal | 2013 | Int Urol Nephrol2013，45，10： | 1 |
| 18 | Converter smelting petroleum casing pipe steel and Mn5,37 Mn5 production practice (in Chinese)显示文摘 | Wang WH Li SQ | | 0，，03： | 1 |
| 19 | One stage surgical correction of congenital cardiac disease and congenital tracheal stenosis in infants and children显示文摘 | Xu ZW Li WH | 2009 | Card Surg2009，24，5： | 1 |
| 20 | Middle cerebral artery intraplaque hemorrhage: prevalence and clinical relevance显示文摘 | Xu WH Li ML Gao S | 2012 | Ann Neurol2012，71，： | 1 |
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