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| 1 | Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts' consensus statement显示文摘Since the outbreak of 2019 novel coronavirus infection (2019-nCoV) in Wuhan City,China,by January 30,2020,a total of 9692 confirmed cases and 15,238 suspected cases have been reported around 31 provinces or cities in China.Among the confirmed cases,1527 were severe cases,171 had recovered and been discharged at home,and 213 died.And among these cases,a total of 28 children aged from 1 month to 17 years have been reported in China.For standardizing prevention and management of 2019-nCoV infections in children,we called up an experts' committee to formulate this experts' consensus statement.This statement is based on the Novel Coronavirus Infection Pneumonia Diagnosis and Treatment Standards (the fourth edition) (National Health Committee) and other previous diagnosis and treatment strategies for pediatric virus infections.The present consensus statement summarizes current strategies on diagnosis,treatment,and prevention of 2019-nCoV infection in children. | Kunling Shen Yonghong Yang Tianyou Wang Dongchi Zhao Yi Jiang Runming Jin Yuejie Zheng Baoping Xu Zhengde Xie Likai Lin Yunxiao Shang Xiaoxia Lu Sainan Shu Yan Bai Jikui Deng Min Lu Leping Ye Xuefeng Wang Yongyan Wang Liwei Gao | 2020 | World Journal of Pediatrics2020，16，3： | 56 |
| 2 | Magnetostratigraphy and paleoenvironmental record of Tertiary deposits of Lanzhou Basin显示文摘The Tertiary deposits of the Yongdeng section, the Lanzhou Basin were studied by means of magnetostrati-graphy. The magnetostratigraphic sequences from Paleocene to Miocene were established, and the time scale for the corresponding stratigraphy and mammalian faunas was also established by referring to their correlation to the GPTS of BKSA95 (The geomagnetic polarity time scale which was thoroughly revised and updated by Berggreen et al. in 1995). In the end the paleoenvironmental records and their relationship with the uplifting of the Tibetan Plateau were discussed. The results are as follows. The top boundary of the Xiliugou Formation is dated to be 51 Ma, i.e. Eocene. TheYehucheng Formation covers the time span of 51-31.5 Ma, i.e. from late Early Eocene to early Early Oligocene. The Xianshuihe Formation covers the time span of 31.5-15 Ma, i.e. from Early Oligocene to Middle Miocene. The lower member of the Xianshuihe Formation spans from 31.5 to 20.0 Ma, i.e. from Early Oligocene to early Early | YUE Leping F.Heller QIU Zhanxiang ZHANG Li XIE Guangpu QIU Zhuding ZHANG Yunxiang | 2001 | Chinese Science Bulletin2001，46，9： | 28 |
| 3 | Homology-mediated end joining-based targeted integration using CRISPR/Cas9显示文摘 | Yao, Xuan Wang, Xing Hu, Xinde Liu, Zhen Liu, Junlai Zhou, Haibo Shen, Xiaowen Wei, Yu Huang, Zijian Ying, Wenqin Wang, Yan Nie, Yan-Hong Zhang, Chen-Chen Li, Sanlan Cheng, Leping Wang, Qifang Wu, Yan Huang, Pengyu Sun, Qiang Shi, Linyu Yang, Hui | 2017 | Cell Research2017，27，6： | 28 |
| 4 | Assessment on heavy metals pollution of agricultural soil in Guanzhong District显示文摘The monitored soil samples were collected from Heihui irrigated area, Jiaokou irrigated area, Qianhe river valley and Jinghe river valley (hereafter Heihui, Jiaokou, Qianhe and Jinghe for short respectively) of Guanzhong District. According to the Environment Quality Standard for Soil (GB15618-1995II), we evaluated the pollution status of heavy metals (Cd, As, Cr and Pb) that could seriously endanger soil environment and human health by using single-factor index and synthetic pollution index methods. The results indicate that the synthetic pollution indices P of soil heavy metals are less than 0.7 in Heihui, Jiaokou, Qianhe and Jinghe of Guanzhong, the single-factor indices Pi of soil heavy metals of most soil samples are less than 0.7, so the soil environmental quality is in a good condition in Guanzhong on the whole; the enrichment degree of soil heavy metals is in the order of Heihui, Jinghe, Qianhe and Jiaokou; the contaminated degree of soil heavy metals has the feature of Cd > As > Cr > Pb; heavy metals contents in the cultivated horizon soil are generally higher than those in its underlayer soil, heavy metals contents of soil have the characteristic of enriching towards the cultivated horizon; Cd exceeds standard in the soil samples HS07a, b and HS08a, b at the Yangtao orchard in Heihui and in the soil sample QHS01a at the suburban vegetable plot in Qianhe, which was mainly caused by the long-term irrational use of chemical fertilizer and pesticide. | ZHENG Guozhang YUE Leping LI Zhipei CHEN Chao | 2006 | Journal of Geographical Sciences2006，16，1： | 21 |
| 5 | Starch grain analysis reveals ancient diet at Kuahuqiao site,Zhejiang Province显示文摘Charred residues adhering to sherds of ceramic cooking vessels,pots (Fu),excavated from the Kuahuqiao site (8000-7000 cal a BP) in Zhejiang Province were examined using the method of starch grain analysis.Ancient starch grains were recovered from charred residues and were classified into 8 genera.Remains from rice (Oryza spp.),job's-tears (Coix chinesis T.),bean (Vigna spp.),acorn (Quercus spp.) as well as possibly buckeye tree (Aesculus chinensis B.) were identified.Other starch grains from unidentified plants were also recovered.Tracheids with bordered pits from softwood fibers were also found,indicating that some food might have been processed with wooden tools.The range of starch grains in the charred residues adhering to the ceramic pots reveals the diversity of ancient plant foods at the Kuahuqiao site,Zhejiang Province. | YANG XiaoYan JIANG LePing | 2010 | Chinese Science Bulletin2010，55，12： | 20 |
| 6 | An investigation on tether-tugging de-orbit of defunct geostationary satellites显示文摘In recent years,defunct satellites mitigation in the geostationary orbit(GEO) has become a hot issue in the space field.How to transfer defunct geostationary satellites to the graveyard orbit safely,economically and efficiently presents new challenges to spacecraft dynamics and control.This paper conducts an in-depth investigation on tether-tugging de-orbit issues of defunct geostationary satellites.Firstly,a four-phase tether-tugging de-orbit scheme including acceleration,equilibrium,rotation and return is proposed.This scheme takes into consideration how to avoid the risks of tether ripping,tug-target collision,and tether twist,and how to achieve the mission objective of fuel saving.Secondly,the dynamics model of the tether combination system is established based on Lagrange equation,and the four phases of tether-tugging de-orbit scheme are simulated respectively.Simulation results indicate that the scheme is theoretically feasible and satisfies the design objectives of safety,economy and efficiency,providing a technical approach for engineering application. | LIU HaiTao YANG LePing ZHANG QingBin ZHU YanWei | 2012 | Science China(Technological Sciences)2012，55，7： | 18 |
| 7 | Hypoxia-inducible factor-lαand semaphorin4D genes involved with tumor-associated macrophage-induced metastatic behavior and clinical significance in colon cancer显示文摘 | Mu Linjun Wang Jinshen Chen Yuezhi Li Leping Guo Xiaobo Zheng Sheng Jing Changqing | 2014 | Chinese Medical Journal2014，，20： | 15 |
| 8 | EXPONENTIAL STABILITY OF LINEAR DISTRIBUTED PARAMETER SWITCHED SYSTEMS WITH TIME-DELAY显示文摘In this paper, the exponential stability analysis for ODE switched systems with time delay is extended to distributed parameter switched systems(DPSS) in Hilbert space. For a given family of exponential stable subsystems, this paper focuses on finding conditions to guarantee the overall DPSS' exponential stability. Based on semigroup theory, by applying piecewise Lyapunov-Krasovskii functionals method incorporated average dwell time approach, sufficient conditions for exponential stability are derived. These conditions are given in the form of linear operator inequalities(LOIs)where the decision variables are operators in Hilbert space, and the stability properties depend on switching rule. Being applied to heat switched propagation equations, these LOIs are reduced to standard Linear Matrix Inequalities(LMIs). Finally, a numerical example is given to illustrate the effectiveness of the proposed result. | BAO Leping FEI Shumin YU Lei | 2014 | Journal of Systems Science & Complexity2014，27，2： | 9 |
| 9 | Taxonomy,age and environment status of the Yuanmou hominoids显示文摘The taxonomy, age and environment status of the Yuanmou hominoids had been contro-versial since their discovery. We launched new ex-cavations and investigations in the Yuanmou Basin and analyzed both old and newly collected data. We conclude that all hominoids from the Yuanmou Basin and the so-called Pliocene hominids can be attributed into a single species, and its valid nomination is Lufengpithecus hudienensis. It is different from Lufengpithecus lufengensis and Lufengpithecus kei-yuanensis. Based on the faunal comparison and pa-leomagnetic correlation, the strata yielding the Yuanmou hominoids are older than those of Lufeng hominoids and younger than those of the Kaiyuan hominoids. The age of the Yuanmou hominoids is Late Miocene. The environments of the Yuanmou hominoids were subtropical, hilly, with some dense forestry and partial transitional bushes and seasonal climate. | QI Guoqin DONG Wei ZHENG Liang ZHAO Lingxia GAO Feng YUE Leping ZHANG Yunxiang | 2006 | Chinese Science Bulletin2006，51，6： | 9 |
| 10 | Preparation and characterization of microcapsule containing epoxy resin and its self-healing performance of anticorrosion covering material显示文摘Microencapsulated healing agents that possess adequate strength,long shelf-life,and excellent bonding to the host material are required for self-healing materials. The in situ encapsulation method is demonstrated over an order of magnitude size reduction for the preparation of urea-formaldehyde(UF) capsules filled with a healing agent,a mixture epoxy resin of the epoxy 711 and E-51. Capsules with diameters as small as about 100 μm are achieved under the agitation rate of 800 r min-1. The capsules possess a uniform UF shell wall(4 μm average thickness) . By using the analysis of scanning electronic microscope(SEM) ,thermal analysis(TG-DTA) and FTIR,the characteristics of the microcapsules were investigated respectively. Successful self-healing has been demonstrated for anticorrosion covering materials with microcapsules. | LIAO LePing ZHANG Wei XIN Yi WANG HongMei ZHAO Yang LI WuJun | 2011 | Chinese Science Bulletin2011，56，4： | 8 |
| 11 | Evolution of the Ordos Plateau and environmental effects显示文摘Based on the analysis of temporary-spatial distribution, geomorphic position, contact relationship with underlying strata and grain size of red clay, we studied the formation and environmental background of red clay. During late Miocene-Pliocene, the Ordos Block finished the transformation from the basin to the plateau, which had an obvious environmental effect on the topography, indicated by the formation of highland undergoing wind erosion and lowland receiving red clay deposits. The red clay materials were sourced from dusts carried by wind energy and covered on the initial topography. Unlike Quaternary loess dust covering the overall the Loess Plateau, red clay deposited on the highland would be transported to the lowlands by wind and fluvial process. As a result, there was no continuous 'Red Clay Plateau' in the Ordos region and red clay was only preserved in former lowlands. However, red clay was discontinuously distributed through the Loess Plateau and to some extent modified the initial topography. The differential uplift in interior plateau is indicated by the uplift of northern Baiyushan, central Ziwuling and southern Weibeibeishan. The Weibeibeishan Depression formed earlier and became the sedimentary center of red clay resulting in the thicker red clay deposits in Chaona, Lingtai and Xunyi. Since Quaternary the aridity in the northern plateau enhanced and accelerated loess accumulation caused the formation of the Loess Plateau. During the late Pleistocene the rapid uplift led to the enhancement of erosion. Especially after the cut-through of Sanme Lake by the Yellow River, the decline of base level caused the falling of ground water level and at the same time the increase of drainage density resulting in the enhancement of evaporation capacity, which enhanced the aridity tendency of aridity in the Loess Plateau region. | YUE LePing LI JianXing ZHENG GuoZhang LI ZhiPei | 2007 | Science China Earth Sciences2007，50，z2： | 8 |
| 12 | Sex determination and maintenance: the role DMRT1 and FOXL2显示文摘 | Shengsong Huang Leping Ye Haolin Chen | 2017 | Asian Journal of Andrology2017，19，6： | 8 |
| 13 | A New Fire Detection Method Using a Multi-Expert System Based on Color Dispersion, Similarity and Centroid Motion in Indoor Environment显示文摘In this paper, a video fire detection method is proposed, which demonstrated good performance in indoor environment. Three main novel ideas have been introduced. Firstly, a flame color model in RGB and HIS color space is used to extract pre-detected regions instead of traditional motion differential method, as it’s more suitable for fire detection in indoor environment. Secondly, according to the flicker characteristic of the flame, similarity and two main values of centroid motion are proposed. At the same time, a simple but effective method for tracking the same regions in consecutive frames is established. Thirdly,a multi-expert system consisting of color component dispersion,similarity and centroid motion is established to identify flames.The proposed method has been tested on a very large dataset of fire videos acquired both in real indoor environment tests and from the Internet. The experimental results show that the proposed approach achieved a balance between the false positive rate and the false negative rate, and demonstrated a better performance in terms of overall accuracy and F standard with respect to other similar fire detection methods in indoor environment. | Teng Wang Leping Bu Zhikai Yang Peng Yuan Jineng Ouyang | 2020 | IEEE/CAA Journal of Automatica Sinica2020，7，1： | 7 |
| 14 | Function of Ca^(2+)-/calmodulin-dependent protein kinase Ⅳ in Ca^(2+)-stimulated neuronal signaling and behavior显示文摘The activity of Ca2+/calmodulin-dependent protein kinase IV(Ca MKIV) is sensitive to activity-dependent changes in the level of intracellular Ca2+.Following neuronal stimulation,the activation of Ca MKIV may trigger synaptic modifications and transcriptional responses,both of which are involved in regulating cognitive and emotional behavior.Here,we used Ca MKIV knockout(KO) neurons and mice to examine the function of Ca MKIV in Ca2+-stimulated intracellular signaling and animal behavior,respectively.Following NMDA receptor activation or membrane depolarization,the up-regulation of CREB(c AMP responsive element binding protein) and its target gene Bdnf(brain-derived neurotrophic factor) was intact in cortical neurons obtained from Ca MKIV KO mice.Ca MKIV KO mice displayed severe impairment in contextual fear memory but normal locomotor activity and anxiety level in the contextual training chamber.Although Ca MKIV KO mice showed normal memory in the standard passive avoidance task,they were defective in learning the temporal dissociative passive avoidance task.As indicated by the light/dark test and marble-burying test data,Ca MKIV KO mice showed less anxiety and normal perseveration.In the voluntary wheel-running test,Ca MKIV KO mice showed normal running time and distance but higher maximal running speed.Our results demonstrate the function of Ca MKIV in regulating different forms of fear memory,anxiety,and certain aspect of motor function. | SONG ZiXiang CHEN Qi DING Qi ZHENG Fei LI ChengWei XU LePing WANG HongBing | 2015 | Science China(Life Sciences)2015，58，1： | 6 |
| 15 | Semi-solid slurry preparation and rolling of 1Cr18Ni9Ti stainless steel显示文摘The preparation and rolling of the semi-solid slurry 1Crl8Ni9Ti stainless steel were researched. The experimental results show that when stirred for 2-3 min under the given test condition, the semi-solid slurry with about 50%-60% (volume fraction) solid and the spherical primary austenitic grains in the size of 100-200 μm can be obtained, and it is easy to be discharged from the bottom little hole of the stirring chamber. The semi-solid slurry of 1Crl8Ni9Ti stainless steel can be rolled into the given plate successfully.However, the solid phase and liquid phase are easily separated in the rolling process, so that the solid primary austenitic grains are concentrated in the center and the liquid phase is near the edge of the rolled plate. The strengths of the plate rolled in the semi-solid state are higher than that of the traditionally repeated hot-rolled plate of 1Cr18Ni9Ti stainless steel. | Weimin Mao, Aimin Zhao, Dong Yun, Leping Zhang, and Xueyou ZhongMaterials Science and Engineering School, University of Science and Technology Beijing, Beijing 100083, China | 2003 | Journal of University of Science and Technology Beijing2003，10，6： | 6 |
| 16 | Environmental change since mid-Pleistocene recorded in Shangshan achaeological site of Zhejiang显示文摘在迟了的时期的大约 173 ka BP 中间 -- 更新世,河的第二个平台被形成了由于因为气候,海水平变化和构造行动,高举发生在 Shangshan 区域。在 173 75 ka BP 之间。 | MAO Longjiang MO Duowen JIANG Leping JIA Yaofeng LIU Xiaoyan LI Minglin ZHOU Kunshu SHI Chenxi | 2008 | Journal of Geographical Sciences2008，18，2： | 6 |
| 17 | Formation keeping control through inter-satellite electromagnetic force显示文摘Satellite formation keeping through inter-satellite electromagnetic force provides an attractive alternative for future space missions due to its distinct advantages of no propellant consumption or plume contamination as compared to conventional approaches.However,the internal force nature as well as the high nonlinearity and coupling of electromagnetic force brings new control challenges for this novel technique.In this paper,analysis on the dynamics characteristics and special control issues in the presence of electromagnetic force is carried out on the basis of the derived relatively translational dynamics.Considering the model uncertainties,external disturbances and sensor noise,a combined nonlinear control scheme involving feed-forward and feedback control components is proposed for electromagnetic-force-based formation keeping.The feed-forward component is directly obtained through desired configuration and dynamics under nominal conditions while the feedback component is realized utilizing active disturbance rejection control methodology with some reasonable improvement.Numerical simulation is presented to verify the feasibility and validity of the combined control scheme. | CAI WeiWei YANG LePing ZHU YanWei ZHANG YuanWen | 2013 | Science China(Technological Sciences)2013，56，5： | 4 |
| 18 | Pedogenesis affecting the Matuyama-Brunhes polarity transition recorded in Chinese loess?显示文摘A detailed record of the Matuyama-Brunhes (M-B) transition has been obtained from the loess unit 8 (L8) at Duanjiapo (34.2° N, 109.2° E), Shannxi Province of China. An investigation of the rock magnetic properties using hysteresis loops, thermomagnetic analyses identifies pseudo-single domain magnetite as the main carrier of the rema-nence, with a small contribution from maghemite and hema-tite. The paleo-direction records obtained reveal: ( i ) The M-B transition was recorded in the middle and lower part of L8, and comprises of five fast reversals. (ii) The duration of the M-B polarity transition related to the directional change is about 4800 a. (iii) The virtual geomagnetic pole (VGP) path during the transition is confined over Africa, peaked 90° away from the sampling site, in contrast with the results obtained from the Weinan loess section. The different VGPs are probably attributed to the pedogenesis. | QUO Bin ZHU Rixiang Florindo Fabio PAN Yongxin YUE Leping | 2001 | Chinese Science Bulletin2001，46，12： | 4 |
| 19 | Magnetostratigraphic dating of mammalian fossils in Junggar Basin,northwest China显示文摘The first detailed chronology for the late Oligocene to early Miocene continental record in northern Junggar Basin is presented,based on rock magnetic experiments and magnetostratigraphic investiga-tions of a 192 m thick mammal-bearing section in the Ulungur River area. Magnetites and hematites were identified as the main carriers for the characteristic remanent magnetization,and the resulting polarity sequence allows an unambiguous correlation to the geomagnetic polarity time scale (GPTS). Furthermore,the Tieersihabahe fauna layer occurs below the Paleocene/Neocene boundary,and the Suosuoquan fauna layer is just above the Neocene onset. Therefore,the age of the Tieersihabahe fauna and Suosuoquan fauna layers can be definitely estimated to be about 25.2 Ma and 22.5 Ma,respectively. | ZHANG Rui YUE LePing WANG JianQi | 2007 | Chinese Science Bulletin2007，52，11： | 3 |
| 20 | Preparation of Spherical FePO4 by Chemical Co-precipitation Combined with Spray-Drying显示文摘Well-shaped spherical agglomerates of FePO4 particles were prepared by a novel method:chemical co-precipitation combined with spray-drying.Tap density analysis,Brunauer-Emmett-Teller analysis,characterizations of X-ray diffraction,scanning electron microscopy,and transmission electron microscopy confirmed that the micron-sized spherical agglomerates with high specific surface area and high tap density were composed of the uniform nano-sized particles.The effects of pH and reaction time on the morphology of the FePO4 particles were investigated by experimental and theoretical analyses.The analyses revealed that amorphous FePO4 was responsible for forming a well-shaped spherical agglomerate,and the ideal spherical particles were obtained at pH 3.The reaction time also played a significant role in controlling the size and surface morphology of the FePO4 particles,and smooth spherical FePO4 particles were obtained at a reaction time of 6 h.By this novel method,poly-porous spherical iron phosphate particles were prepared,which can be used with high efficiency in some special fields,especially as a precursor for synthesizing LiFePO4 and catalysts. | Leping Dang Hongtao Zhang Xin Xu Xiaojun Lang | 2020 | Transactions of Tianjin University2020，26，1： | 3 |
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