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| 1 | Anatomically realistic multiscale models of normal and abnormal gastrointestinal electrical activity显示文摘One of the major aims of the International Union of Physiological Sciences (IUPS) Physiome Project is to develop multiscale mathematical and computer models that can be used to help understand human health. We present here a small facet of this broad plan that applies to the gastrointestinal system. Specifically, we present an anatomically and physiologically based modelling framework that is capable of simulating normal and pathological electrical activity within the stomach and small intestine. The continuum models used within this framework have been created using anatomical information derived from common medical imaging modalities and data from the Visible Human Project. These models explicitly incorporate the various smooth muscle layers and networks of interstitial cells of Cajal (ICC) that are known to exist within the walls of the stomach and small bowel. Electrical activity within individual ICCs and smooth muscle cells is simulated using a previously published simplified representation of the cell level electrical activity. This simulated cell level activity is incorporated into a bidomain representation of the tissue, allowing electrical activity of the entire stomach or intestine to be simulated in the anatomically derived models. This electrical modelling framework successfully replicates many of the qualitative features of the slow wave activity within the stomach and intestine and has also been used to investigate activity associated with functional uncoupling of the stomach. | Leo K Cheng Rie Komuro Travis M Austin Martin L Buist Andrew J Pullan | 2007 | World Journal of Gastroenterology2007，13，9： | 3 |
| 2 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021，59，4： | 3 |
| 3 | Superior ena caa resection for lung and mediastinal malignancies:a single-center experience with 70 cases显示文摘 | Spaggiari L Leo F eronesi G | 2007 | Ann Thorac Surg2007，83，1： | 1 |
| 4 | Seismic monitoring of a CO2 flood at Weyburn field,Saskatchewan, Canada: Demonstrating the robustness of time-lapse seismology显示文摘 | Davis T L Brown Leo | 2002 | Expanded Abstracts of 72nd Annual Internat SEG Mtg2002，，： | 1 |
| 5 | 3 ' ,4' -dihydroxyflavonol re- duces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries显示文摘 | Leo C H Hart J L Woodman 0 L | 2011 | PLoS One2011，6，20： | 1 |
| 6 | Nailsalvage using the eponychia l flap显示文摘 | Adan R Leo G Tarallo L | 2006 | Tech Extrem Surg2006，10，4： | 1 |
| 7 | Signal processing for FMCW SAR显示文摘 | Meta A Hoogeboom P and Leo P L | 2007 | IEEE Transactions on Geoseence and Remote SensiTg2007，45，35： | 1 |
| 8 | Fault detection in industrial:Processes using canonical varitae analysis and dynamic principal component analysis显示文摘 | Evan L R Leo H | 2000 | Chemo mettles and Intelligent:Laboratory Systems2000，51，8： | 1 |
| 9 | The role of IL-113 and TNF-ct signaling in the genesis of cancer treatment related symptoms(CTRS):a study using cytokine receptor--deficient mice显示文摘 | SMITH L B LEO M C ANDERSON C | 2014 | Brain Behavior and Immunity2014，，38： | 1 |
| 10 | Hypoxia and expression of the proapoptotic regulator BNIP3 in cervical cancer显示文摘 | HORN L C | 2006 | Int J Gynecol Cancer2006，16，： | 1 |
| 11 | Endiocrine and metaboli effects of insulin sensitizers in the treatment of patients with poly- cystic ovary syndrome and hyperinsulinaemia显示文摘 | Ciotta L De Leo V Farina M | 2001 | Gynecol Obstet Invest2001，51，1： | 1 |
| 12 | Nail salvage using the eponychial flap显示文摘 | Adani R Leo G Tarallo L | | 0，，04： | 1 |
| 13 | Generalized Minimax inequalities for set-valued mappings 显示文摘 | Li S J Chen G Y Leo K L | 2003 | J Math Anal Appl2003，281，： | 1 |
| 14 | Action of sodium silicate as a corro- sion inhibitor in water piping 显示文摘 | Leo L Shuldener H L | 1952 | Industry and Engineering Chemistry1952，44，8： | 1 |
| 15 | Recent improvements to the SMART domain-based sequence annotation resource显示文摘 | Ivica L Leo G Nicholas JD | 2002 | Nucleic Acids Research2002，30，： | 1 |
| 16 | Maternal anthropometric factors and risk of primary cesarean delivery显示文摘 | Shepard M J Saftlas AF Leo - Summers L | 1998 | Am J Public Health1998，88，10： | 1 |
| 17 | Final overall surviv- al: fulvestrant 500rag vs 250rag in the randomized CONFIRM trial显示文摘 | Di Leo A Jerusalem G Petruzelka L | 2014 | J Nati Cancer Inst2014，106，1： | 1 |
| 18 | Biology of Influenza a Virus显示文摘 | Timothy K Cheung W Leo L | 2007 | Ann N Y Acad Sci2007，1102，： | 1 |
| 19 | Platelet activation by superoxide anion and hydroxyl radicals intrinsically generated by platelets that had undergone anoxia and than reoxygenated显示文摘 | Leo R Pratico D Iuliano L | 1997 | Circulation1997，95，4： | 1 |
| 20 | Platelet activation by superoxide anion and hydroxyl radicals intrinsically generated by platelets that had undergone anoxia and than reoxygenated显示文摘 | Leo R Pratieo D Iuliano L | 1997 | Circulation1997，95，5： | 1 |
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