|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Genome survey uncovers the secrets of sex and lifestyle in caterpillar fungus显示文摘The caterpillar fungus Ophiocordyceps sinensis (best known as Cordyceps sinensis) mummifies ghost moth larvae exclusively in Tibetan Plateau alpine ecosystems. Touted as 'Himalayan Viagra', the fungus is highly prized due to its medical benefits and dwindling supplies. Attempts to culture the sexual fruiting-body have failed and the huge market demand has led to severe devastation of local ecosystems and to the fungus heading towards extinction. By genome sequencing, we establish that unlike related insect pathogens O. sinensis contains two compatible mating-type genes in its genome and is self-fertile, i.e. homothallic. However, sexual processes are only initiated under native environmental conditions. O. sinensis resembles biotrophic plant pathogens in having a genome shaped by retrotransposon-driven expansions. The resulting changes in gene content suggest that O. sinensis has a biphasic pathogenic mechanism beginning with stealth pathogenesis in early host instars. O. sinensis is the first psychrophilic fungus sequenced and is adapted to extreme cold with putative antifreeze proteins and mechanisms for increasing lipid accumulation and fatty acid unsaturation. We hypothesize that for the inbreeding O. sinensis the massive proliferation of retrotransposons provides a tradeoff between the advantages of increased genetic variation independent of sexual recombination and deletion of genes dispensable for its specialized pathogenic lifestyle. | HU Xiao ZHANG YongJie XIAO GuoHua ZHENG Peng XIA YongLiang ZHANG XingYu ST LEGER Raymond J LIU XingZhong WANG ChengShu | 2013 | Chinese Science Bulletin2013，58，23： | 26 |
| 2 | 中法高中数学课标微积分内容比较研究显示文摘为追求更高的教学质量,中法两国一直不断地调整高中微积分的教学内容.比较法国2010和2011年公布的高中最新数学大纲中的微积分与中国2003年颁布的《高中数学课程标准》中的微积分内容,建议中国高中微积分教学应缩小知识跨度,加强分层教育,注重微积分与实际以及其它学科的联系,且进一步加强微积分教学与信息技术的整合. | 张玉环 Alain Leger | 2014 | 数学教育学报2014，23，2： | 7 |
| 3 | Thioredoxins Play a Crucial Role in Dynamic Acclimation of Photosynthesis in Fluctuating Light显示文摘 | Ina Thormahlen Arkadius Zupok Josephin Rescher Jochen Leger Stefan Weissenberger Julia Groysman Anne Orwat Gilles Chatel-lnnocenti Emmanuelle Issakidis-Bourguet Ute Armbruster Peter Geigenberger | 2017 | Molecular Plant2017，10，1： | 4 |
| 4 | Generalized Derivation of Lie Algebras 显示文摘 | George F Leger Eugene M Luks | 2000 | J Algebra2000，228，： | 2 |
| 5 | On the computation of seismic energy in inelastic structures显示文摘 | Ande Filiatrault Pierre Leger and Rene Tinawi | 1994 | Engineering Structures1994，16，6： | 1 |
| 6 | A thyroxine dosage of 8 μg/kg per day is appropriate for theinitial theatment of the majority of infants with long enital pothyroidism显示文摘 | TOUATI G LEGER J TOUBLANC JE | 1997 | Eur J Pe diatr1997，156，： | 1 |
| 7 | An Adaptive Brokerage Tool Based on Multi-Agent Framework 显示文摘 | Gleizes M P Glize P Leger A | 1996 | IEEE Computer Communications1996，6，15： | 1 |
| 8 | Brain serotonergic circuitries显示文摘 | Charnay Y Leger L | 2010 | Di- alogues Clin Neurosci2010，12，4： | 1 |
| 9 | Differential gene expression by Metarhizium anisopliae growing in root exudate and host(Manduca sexta)cuticle or hemolymph reveals mechanisms of physiological adaptation显示文摘 | Wang C S Hu G St Leger R J | 2005 | Fungal Genetics and Biology2005，42，： | 1 |
| 10 | Thickened pituitary stalk on magnetic resonance imaging in children with central diabetes insipidus显示文摘 | Leger J Velasquez A Garel C | 1999 | J Clin Endocrinol Metab1999，84，6： | 1 |
| 11 | Peripheral vascular effects of thiopental and propofol in humans with artificial hearts显示文摘 | Rouby JJ Andreev A Leger P | 1991 | Anesthesiology1991，75，1： | 1 |
| 12 | Supra- molecular shuttle and protective agent: a multiple role of methylated cyclodextrins in the chemoselective hydrogena- tion of benzene derivatives with ruthenium nanoparticles 显示文摘 | Audrey Nowicki Yong Zhang Bastien Leger | 2006 | Chemical Communications2006，，3： | 1 |
| 13 | Assessmentof body protein: energy status in chronic kidneydisease 显示文摘 | Cano NJ Miolane-Debouit M Leger J | 2009 | Seminars in Nephrology2009，29，1： | 1 |
| 14 | Akt signalling through GSK-3beta, mTOR and Foxol is involved in human skeletal muscle hypertrophy and atrophy显示文摘 | LEGER B CARTONI R PRAZ M | 2006 | J Physiol2006，576，3： | 1 |
| 15 | Selected materials issues associated with space station显示文摘 | Leger L Visentine J Santos-Mason B | 1987 | SAMPE Quarterly1987，18，2： | 1 |
| 16 | Peripheral vascular effects of thiopental and propofol in humans with artificial hearts 显示文摘 | Andreev A Leger P | 1991 | Anesthesiology1991，75，： | 1 |
| 17 | Electrocatalytic oxidation of 1,2-propanediol-Ⅲa kinetic analysis of its oxidation on platinum in acid medium显示文摘 | Leger J M Lamy C | 1988 | Electrochemical Acta1988，33，10： | 1 |
| 18 | Side effect of nasal continuous positive airway pressure in sleep apnea syndrome:study of 193 patients in tow French sleep centers显示文摘 | Pepin JL Leger P Veale D | 1995 | Chest1995，107，： | 1 |
| 19 | Engineering improved mycoinsecticides显示文摘 | St Leger R J Roberts D W | 1997 | Trends in Biotechnology1997，15，： | 1 |
| 20 | Morgan's Compact Mill-Design parameters,applications and operational benefits显示文摘 | Colin Roy Alfred R Leger David L Pariseau | 1982 | Iron and Steel Engineer1982，，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员