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    题名 作者 年代 出处 被引量
1Effect of metabolic structures and energy requirements on curdlan production by Alcaligenes faecalis显示文摘Zheng, ZY Lee, AW Zhan, XB Shi, Z Wang, L Zhu, L Wu, JR Lin, CC 2007中国生物学文摘2007,21,10:13
2Murine lung eosinophil activation and chemokine production in allergic airway inflammation显示文摘Eosinophils play important roles in asthma and lung infections.Murine models are widely used for assessing the functional significance and mechanistic basis for eosinophil involvements in these diseases.However,little is known about tissue eosinophils in homeostasis.In addition,little data on eosinophil chemokine production during allergic airway inflammation are available.In this study,the properties and functions of homeostatic and activated eosinophils were compared.Eosinophils from normal tissues expressed costimulation and adhesion molecules B7-1,B7-2 and ICAM-1 for Ag presentation but little major histocompatibility complex(MHC)class II,and were found to be poor stimulators of T-cell proliferation.However,these eosinophils expressed high levels of chemokine mRNA including C10,macrophage inflammatory protein(MIP)-1a,MIP-1c,MIP-2,eotaxin and monocyte chemoattractant protein-5(MCP-5),and produced chemokine proteins.Eosinophil intracellular chemokines decreased rapidly with concomitant surface marker downregulation upon in vitro culturing consistent with piecemeal degranulation.Lung eosinophils from mice with induced allergic airway inflammation exhibited increased chemokines mRNA expression and chemokines protein production and upregulated MHC class II and CD11c expression.They were also found to be the predominant producers of the CCR1 ligands CCL6/C10 and CCL9/MIP-1c in inflamed lungs.Eosinophil production of C10 and MIP-1c correlated with the marked influx of CD11bhigh lung dendritic cells during allergic airway inflammation and the high expression of CCR1 on these dendritic cells(DCs).The study provided baseline information on tissue eosinophils,documented the upregulation of activation markers and chemokine production in activated eosinophils,and indicated that eosinophils were a key chemokine-producing cell type in allergic lung inflammation.C Edward Rose Jr Joanne A Lannigan Paul Kim James J Lee Shu Man Fu Sun-sang J Sung 2010Cellular & Molecular Immunology2010,7,5:6
3Role of illness perception and self-efficacy in lifestyle modification among non-alcoholic fatty liver disease patients显示文摘AIM To describe the relationships between non-alcoholic fatty-liver disease(NAFLD) patient's disease consequences and treatment perceptions, self-efficacy, and healthy lifestyle maintenance. METHODS A cross-sectional study among 146 ultrasound diagnosed NAFLD patients who visited the fatty liver clinic at the TelAviv Medical Center. Eighty-seven of these individuals, participated in a clinical trial of physical activity and underwent fasting blood tests, analyzed at the same lab. Exclusion criteria included positivity for serum HBsA g or anti-HCV antibodies; fatty liver suspected to be secondary to hepatotoxic drugs; excessive alcohol consumption(≥ 30 g/d in men or ≥ 20 g/d in women) and positive markers of genetic or immune-mediated liver diseases. Patients were asked to complete a selfreport structured questionnaire, assembled by the Israeli Center for Disease Control. Nutrition habits were measured using six yes/no questions(0 = no, 1 = yes) adopted from the national survey questionnaire. Participants in the clinical trial completed a detailed semi-quantitative food frequency questionnaire(FFQ) reporting their habitual nutritional intake during the past year. Self-efficacy was assessed by the Self-Efficacy Scale questionnaire, emotional representation, degree of illness understanding, timeline perception, treatment perception and symptoms were measured by the Brief Illness Perception questionnaire. Illness consequences were measured by the Personal Models of Diabetes Interview questionnaire. A path analysis was performed to describe the interrelationships between the patients' illness perceptions, and assess the extent to which the data fit a prediction of nutritional habits.RESULTS The study sample included 54.1% men, with a mean age of 47.76 ± 11.68 years(range: 20-60) and mean body mass index of 31.56 ± 4.6. The average perceived nutrition habits score was 4.73 ± 1.45 on a scale between 0-6, where 6 represents the healthiest eating habits. Most of the study participants(57.2%) did not feel they fully understood what NAFLD is. Better nutritional habits were positively predicted by the degree of illness understanding(β = 0.26; P = 0.002) and selfefficacy(β = 0.25; P = 0.003). Perceptions of more severe illness consequences were related with higher emotional representation(β = 0.55; P < 0.001), which was related with lower self-efficacy(β =-0.17; P = 0.034). The perception of treatment effectiveness was positively related with self-efficacy(β = 0.32; P < 0.001). In accordance with the correlation between self-efficacy and the perceived nutrition habits score, self-efficacy was also correlated with nutrient intake evaluated by the FFQ; negatively with saturated fat(percent of saturated fat calories from total calories)(r =-0.28, P = 0.010) and positively with fiber(r = 0.22, P = 0.047) and vitamin C intake(r = 0.34, P = 0.002). In a sub analysis of the clinical trial participants, objectively measured compliance to physical activity regimen was positively correlated with the self-efficacy level(r = 0.34, P = 0.046). CONCLUSION Self-efficacy and illness understanding are major determinants of lifestyle-modification among NAFLD patients. This information can assist clinicians in improving compliance with lifestyle changes among these patients.Shira Zelber-Sagi Shiran Bord Gali Dror-Lavi Matthew Lee Smith Samuel D Towne Jr Assaf Buch Muriel Webb Hanny Yeshua Assy Nimer Oren Shibolet 2017World Journal of Gastroenterology2017,23,10:6
4Comparison of stem taper models for the four tropical tree species in Mount Makiling, Philippines显示文摘This study was conducted to evaluate the performance of six stem taper models on four tropical tree species, namely Celtis luzonica(Magabuyo),Diplodiscus paniculatus(Balobo), Parashorea malaanonan(Bagtikan), and Swietenia macrophylla(Mahogany) in Mount Makiling Forest Reserve(MMFR), Philippines using fit statistics and lack-of-fit statistics. Four statistical criteria were used in this study, including the standard error of estimate(SEE),coefficient of determination(R^2), mean bias( E),and absolute mean difference(AMD). For the lack-offit statistics, SEE, E and AMD were determined in different relative height classes. The results indicated that the Kozak02 stem taper model offered the best fit for the four tropical species in most statistics. The Kozak02 model also consistently provided the best performance in the lack-of-fit statistics with the best SEE, E and AMD in most of the relative height classes. These stem taper equations could help forest managers and researchers better estimate the diameter of the outside bark with any given height,merchantable stem volumes and total stem volumes of standing trees belonging to the four species of thetropical forest in MMFR.Roscinto Ian C.LUMBRES Azyleah C.ABINO Nelson M.PAMPOLINA Feliciano G.CALORA Jr Young Jin LEE 2016Journal of Mountain Science2016,13,3:4
5Mechanisms of action of arsenic trioxide 显示文摘Miller WH Jr Schipper HM Lee JS 2002Cancer Res2002,62,14:2
6The association of cancer and the nephrotic syndrome显示文摘Lee JC Yamauchi H Hopper J Jr 1966Ann Intern Med1966,64,1:1
7Factors affecting the pullout strength of cancellous bone screws 显示文摘Chapman JR Harrington RM Lee KM 1996J Biomech Eng1996,118,:1
8Identification of potent,se-lective non-peptide CC chemokine receptor-3antagonist that inhibits eotaxin-,eotaxin-2-,and monocyte chemotactic protein-4-induced eosinophil migration显示文摘White JR Lee JM Dede K 2000J Biol Chem2000,275,36:1
9New steroidal alkaloids from an undescribed sponge of the genus Corticium 显示文摘Lee HS Seo Y Rho JR 2001J Nat Prod2001,64,11:1
10Cryoablation for liver cancer显示文摘Hinshaw JL Lee Fr Jr 2007Tech Vasc Interv Radiol2007,10,1:1
11Comparisons of three automated systems for genomic DNA extraction in a clinical diagnostic labo ratory 显示文摘Lee J H Park Y Choi JR 2010Yonsei Med J2010,51,1:1
12Gastrodia elata blume and an active component,p-Hydroxybenzyl alcohol reduce focal ischemic brain injury through antioxidant related gene expressions显示文摘Yu SJ Kim JR Lee CK 2005Biol Pharm Bull2005,28,6:1
13Incidence and outcome of cervical artery dissection: a population-based study 显示文摘Lee VH Brown RD Jr Mandrekar JN 2006Neurology2006,67,10:1
14Effect of a single dose of esmolol on the bispectral index to endotracheal intubation during desflurane anesthesia显示文摘Choi EM Min KT Lee JR 2013Korean J Anesthesiol2013,64,5:1
15Interatrial septal abnormalities and stroke:a meta-analysis of case-control studies显示文摘Overell JR Bone I Lees KR 2000Neurology2000,55,8:1
16Glial tumor necrosis factor alpha (TNFα) generates metaplastic inhibition of spinal learning 显示文摘HUIE JR BAUMBAUER KM LEE KH 2012PLoS ONE2012,7,39:1
17Assessment of injury to the thoracolumbar posterior ligamentous complex in the setting of normal-appearlng plain radiography显示文摘Using magnetic resonance injury to the posterior ligamen- a prospective comparison of the Neurosurg Spine 2010 12(4): Lee JY Vaccaro AR Schweitzer KM Jr 2007Spine J2007,7,4:1
18Potential regulation function of human dendritic cells expressing indoleamine 2,3 -dioxygenasa 显示文摘Munn DH Sharma MD Lee JR 2002Science2002,297,5588:1
19γ-Glutamyltrans-ferase,obesity,and the risk of type 2diabetes:observationalcohort study among 20158middle-aged men and women显示文摘Lee DH Silventoinen K Jacobs DR Jr 2004JClin Endocrinol Metab2004,89,11:1
20Comparative uptake of plutonium from soils by Brassica juncea and Helianthus annuus 显示文摘LEE J H HOSSNER L R ATTREP M Jr 2002Environment Pollution2002,120,2:1
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