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422篇 您的检索式:作者名="LAWSON L"
    题名 作者 年代 出处 被引量
1PrP^C-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site显示文摘铜绑定,抛锚膜的、细胞的 prion 蛋白质(PrPC ) 有二个组成的劈开地点生产不同 N 终端和 C 终端碎片(N1/C1 和 N2/C2 ) 。用表示也人的 PrPC,鼠标 PrPC 或鼠标 PrPC 的 RK13 房间带 3F4 epitope,这研究在 endoproteolytic 劈开和一个通常认为的 PrPC 函数上探索了 PrPC 主要顺序的影响,地图 kinase 信号 transduction,响应外长的铜与或没有使不安的膜环境。PrPC 主要顺序,特别在 N1/C1 劈开地点附近,看起来在这个地点和细胞外的调整信号的 kinase 1/2 (ERK1/2 ) phosphorylation 影响解朊作用的基础层次,与处理激活增加与基础 ERK1/2 表明一种反的关系。人的 PrPC 独自响应铜显示出增加的 N1/C1 劈开,由特定的 p38 和 JNK/SAPK phosphorylation 伴随了。到加扣押胆固醇的抗菌素 filipin 的铜的联合暴露导致了一只老鼠信号蛋白质 phosphorylation 的 PrPC 特定的实质的增加,由 N1/C1 劈开的增加伴随了。怀有人的 N1/C1 劈开地点的老鼠 PrPC 基础地并且响应铜假定更似人类的侧面并且改变了膜环境。我们的结果证明在 N1/C1 劈开地点附近的 PrPC 主要顺序影响在这个地点处理的 endoproteolytic,它显得连接了基础地并且响应铜印射 kinase 信号 transduction。进一步,主要顺序看起来响应外长的刺激在 PrPC 相关的信号 transduction 的忠实上授与 N1/C1 劈开和膜完整的相互的依赖。Cathryn L Haigh 2009Cell Research2009,19,9:4
2HPLC法测定大蒜匀浆中的大蒜辣素及其他硫代亚磺酸酯含量显示文摘用反相高效液相色谱法《C_(18)-HPLC)分离和定量大蒜匀浆中所有可检测的烷基和烯基硫代亚磺酸酯及其构型异构体的含量。首次发现5种新的硫代亚磺酸酯,其中4种含有反式-1-丙烯基。大蒜于4C贮藏时其大蒜辣素含量增加一半以至若干倍,且伴随γ-谷氨酰肽含量降低。研究了硫代亚磺酸酯含量与不同产地、商店、球茎、蒜瓣及储存时间的关系。作者提出一个大蒜辣素的标准定量方法,并与其他的分析方法进行对比。Lawson L D 陈汉平 1992国外医药(植物药分册)1992,7,5:3
3Effect of Copper on the Ultrastructure of the Gill Epithelium of Carcinus maenas ( Decapoda: Brachyura ) 显示文摘LAWSON S L JONES M B MOATE R M 1995Marine Pollution Bulletin1995,31,13:1
4Predicted structure and electronic properties of individual carbon nanocones and nanostructures assembled from nanocones显示文摘Shenderova O A Lawson B L Areshkin D 2001Nanotechnology2001,12,:1
5Pregnancy outcomes after laparoscopic myomectomy with ultrasonic energy and laparoscopic suturing of the endometrial cavity显示文摘Stringer N H Strassner H T Lawson L 2001J Am Assoc Gynecol Lap2001,8,1:1
6The responses of guard and mesophyll ceil photosynthesis to CO2 , light, and water stress in a range of specqes are similar显示文摘Lawson T Oxborough K Morison J L 2003Journal of Experimental Botany2003,54,388:1
7Turnover of res- ident microglia in the normal adult mouse brain 显示文摘Lawson L J Perry VH Gordon S 1992Neuroscience1992,48,2:1
8Basic linear algebra subprograms for Fortran usage显示文摘Lawson C L Hanson R J Kincaid D R 1979ACM Transactions on Mathematical Software1979,5,3:1
9Development and application of molecular marker linkage maps in woody fruit crops显示文摘N F Weeden M Hemmatt D M Lawson M Lodhi R L Bell A G Manganaris B I Reischs S K Brown G N Ye 1994Euphytica1994,77,12:1
10Evidence that pcpA encodes 2,6-dichlorohydroquinone dioxygenase, the ring cleavage enzyme required for pentachlorophenol degradation in Sphingomonas chlorophenolica strain ATCC 39723 显示文摘Xu L Resing K Lawson S L 1999Biochemistry1999,38,:1
11TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus 显示文摘Eldin P Papon L Oteiza A Brocchi E Lawson TG Mechti N 2009J Gen Virol2009,90,3:1
12The Sea21 cell surface marker enriches for a prostate regenerating cell subpopulation that can initiate prostate tumorigenesis显示文摘Xin L Lawson D A Witte O N 2005Proc Natl Aead Sei USA2005,102,19:1
13Pulmonary alveolar proteinosis:clinical aspects and current concepts on pathogenesis显示文摘Pallay L Shah David Hansell Peter R Lawson 2000Thorax2000,55,1:1
14Prospective investigation of positron emission tomography in lung nodules显示文摘Lowe VJ FJ Gobar L Lawson M 1998J Clin On co11998,16,3:1
15The Sca-1 cell surface marker enriches for a prostate -regenerating cell subpopulation that can initiate prostate tumorigenesis显示文摘Xin L Lawson DA Witte ON 2005Proc Natl Acad Sci USA2005,102,20:1
16Basic linear algebra subprograms for Fortran usage显示文摘Lawson C L Hanson R J Kincaid D R 1979ACM Transactions on Mathematical Software1979,5,3:1
17Intrernal coalescence as a mechanism of instability in water-in oil-in-water double-emulsion globules显示文摘Villa C H Lawson L B Li Y Papadoupoulos K D 2003Langmuir2003,19,2:1
18Mercury in the Chesapeake Bay显示文摘Mason R P Lawson N M Lawrence A L 1999Marine Chemistry1999,65,:1
19Heterogeneity in the distribution and morphology of microglia in the normal a- dult mouse brain显示文摘LAWSON L J PERRY V H DRI P 1990Neuroscience1990,39,1:1
20Moisture Effects in Heat Transfer Through Clothing Systems for Wildland Firefighters显示文摘LAWSON L K CROWN E M ACKERMAN M Y 2004In- ternational Journal of Occupational Safety and Ergo- nomics2004,10,3:1
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