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| 1 | Validation of a new scoring system: Rapid assessment faecal incontinence score显示文摘AIM: To implement a quick and simple test- rapid assessment faecal incontinence score(RAFIS) and show its reliability and validity.METHODS: From March 2008 through March 2010, we evaluated a total of 261 consecutive patients, including 53 patients with faecal incontinence. Demographic and comorbidity information was collected. In a single visit, patients were administered the RAFIS. The results obtained with the new score were compared with those of both Wexner score and faecal incontinence quality of life scale(FIQL) questionnaire. The patient withoutinfluence of the surgeon completed the test. The role of surgeon was explaining the meaning of each section and how he had to fill. Reliability of the RAFIS score was measured using intra-observer agreement and Cronbach's alpha(internal consistency) coefficient. Multivariate analysis of the main components within the different scores was performed in order to determine whether all the scores measured the same factor and to conclude whether the information could be encompassed in a single factor. A sample size of 50 patients with faecal incontinence was estimated to be enough to detect a correlation of 0.55 or better at 5% level of significance with 80% power.RESULTS: We analysed the results obtained by 53 consecutive patients with faecal incontinence(median age 61.55 ± 12.49 years) in the three scoring systems. A total of 208 healthy volunteers(median age 58.41 ± 18.41 years) without faecal incontinence were included in the study as negative controls. Pearson's correlation coefficient between 'state' and 'leaks' was excellent(r = 0.92, P < 0.005). Internal consistency in the comparison of 'state' and 'leaks' yielded also excellent correlation(Cronbach's α = 0.93). Results in each score were compared using regression analysis and a correlation value of r = 0.98 was obtained with Wexner score. As regards FIQL questionnaire, the values of 'r ' for the different subscales of the questionnaire were: 'lifestyle' r =-0.87, 'coping/behaviour' r =-0.91, 'depression' r =-0.36 and 'embarrassment' r =-0.90,(P < 0.01). A multivariate analysis showed that all the scoring systems measured the same factor. A single factor may explain 80.84% of the variability of FI, so all the scoring systems measure the same factor. Patient's continence improves when RAFIS and Jorge-Wexner scores show low values and when the values obtained in the FIQL questionnaire are high.CONCLUSION: RAFIS is a valid and reliable tool to assess Faecal Incontinence. | Fernando de la Portilla Arantxa Calero-Lillo Rosa M Jiménez-Rodríguez Maria L Reyes Manuela Segovia-González María Victoria Maestre Ana M García-Cabrera | 2015 | World Journal of Gastrointestinal Surgery2015，7，9： | 5 |
| 2 | Functional study of the transplanted kidney with power Doppler US and time/intensity curves 显示文摘 | Farina R Pennisi F La Rosa M | 2007 | Radiol Med2007，112，： | 1 |
| 3 | Validation of RT-PCR assays for molecular characterization of porcine teschoviruses and enteroviruses 显示文摘 | La Rosa G Muscillo M Di Grazia A | 2006 | J Vet Med B2006，53，6： | 1 |
| 4 | Clinical predictors of obstructive sleep apnea显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，： | 1 |
| 5 | Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of beta-catenin and inhibition of beta-catenin-mediated transactivation 显示文摘 | Cervello M Giannitrapani L La Rosa M | 2004 | Int J Mol Med2004，13，5： | 1 |
| 6 | Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor显示文摘 | Colston JT de la Rosa SD Koehler M | 2007 | Am J Physiol Heart Circ Physiol2007，293，3： | 1 |
| 7 | How cyclodextrin incorporation affects the properties of protein-loaded PLGA-based microspheres:the case of insulin/hydroxypropyl-beta-cyclodextrin system显示文摘 | De Rosa G Larobina D Immacolata La Rotonda M | 2005 | J Control Release2005，102，1： | 1 |
| 8 | Slow regularization through chaotic oscillation transfer in an unidirectional chain of H-R models显示文摘 | Rosa M La Rabinovich M I Huerta R | 2000 | Phys Lett A2000，266，： | 1 |
| 9 | SEPIVAC:a community-based study of stroke incidence in Umbria,Italy显示文摘 | Celani M G La Rosa F | 1991 | J Neurol Neurosurg Psychiatry1991，54，： | 1 |
| 10 | Tri-substitued trizoles as potent non-nucleoside inhibitors of the HIV-1 reverse transcriptase显示文摘 | DE LA ROSA M KIM HW GUNIC E | 2006 | Bioorg Med Chem Lett2006，16，17： | 1 |
| 11 | Clinical predictors of obstructive sleep apnea显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，12： | 1 |
| 12 | Clinical predictors of obstructive sleep apnea 显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，： | 1 |
| 13 | DirectDetection of Black Carbon in Soils by Py-GC/MS,Carbon-13 NMRSpectroscopy and Thermogravimetric Techniques显示文摘 | DE LA ROSA J M KNICKER H LóPEZ-CAPEL E | 2008 | Soil ScienceSociety of America Journal2008，72，： | 1 |
| 14 | Proteomic characterization of adipose tissue constituents, a necessary step for understanding adipose tissue complexity 显示文摘 | Peinado JR Pardo M de la Rosa | 2012 | Proteomics2012，12，45： | 1 |
| 15 | A chemical speciation of trace metals for fine urbanparticles 显示文摘 | Espinosa A J F Rodriguez M T De La Rosa F J B | 2002 | Atmospheric Environment2002，36，5： | 1 |
| 16 | Clinical predictors of obstructive sleep apnea显示文摘 | Friedman M Tanyeri H La Rosa M | 1999 | Laryngoscope1999，109，12： | 1 |
| 17 | Bioactive peptides in amaranth (Amaranthus hypochondriacus) seed显示文摘 | Silva-Sa'nchez C de la Rosa A P León-Galván M F | 2008 | J Agric Food Chem2008，56，4： | 1 |
| 18 | Ensuring correctness during process configuration via partner synthesis 显示文摘 | Van der Aalst Wil M P Lohmann Niels La Rosa | 2012 | Information System2012，37，6： | 1 |
| 19 | Molecular identification and typing of enterovimses isolated from clinical specimens 显示文摘 | Manzara S Muscillo M La Rosa G | 2002 | J Clin Microbiol2002，40，12： | 1 |
| 20 | Post-Miocene expansion, colonization, and host switching drove speciation among extant nematodes of the archaic genus Trichinella 显示文摘 | Zarlenga D S Rosenthal B M La Rosa G | 2006 | Proc Natl Acad Sci U S A2006，103，19： | 1 |
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