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| 1 | Asymmetric dimethylarginine, a biomarker of cardiovascular complications in diabetes mellitus显示文摘Cardiovascular(CV) complications are an essential causal element of prospect in diabetes mellitus(DM), with carotid atherosclerosis being a common risk factor for prospective crisis of coronary artery diseases and/or cerebral infarction in DM subjects. From another point of view, asymmetric dimethylarginine(ADMA) has been established as an inhibitor of endogenous nitric oxide synthesis and the relationship between ADMA and arteriosclerosis has been reported. In our study with 87 type 2 DM(T2DM) patients, we have examined whether ADMA and other CV risk factors are the useful predictors of DMCV complications. After the measurement of the respective CV risk factors, we have followed the enrolled T2 DM patients for 5 years. We have finally analyzed 77 patients. DMCV complications developed in 15 cases newly within 5 years, and 4 cases recurred. The concentrations of ADMA in plasma were markedly more elevated in 19 DM patients with CV complications than in 58 DM patients without CV complications. Urinary albumin(U-Alb), mean intimal-medial thickness(IMT) and ankle brachial index(ABI) were also higher in patients with CV complications. Multiple regression analyses showed that U-Alb had an influence on the high level of ADMA(standardized β = 6.59, P = 0.00014) independently of age, systolic BP, fibrinogen, mean IMT, plaque score, and ABI. The review indicates what is presently known regarding plasma ADMA that might be a new and meaningful biomarker of CV complications in DM subjects. | Hiroyuki Konya Masayuki Miuchi Kahori Satani Satoshi Matsutani Yuzo Yano Taku Tsunoda Takashi Ikawa Toshihiro Matsuo Fumihiro Ochi Yoshiki Kusunoki Masaru Tokuda Tomoyuki Katsuno Tomoya Hamaguchi Jun-ichiro Miyagawa Mitsuyoshi Namba | 2015 | World Journal of Experimental Medicine2015，5，2： | 16 |
| 2 | Enhanced Photocatalytic Activity of TiO2 Nanofibers and Their Flexible Composite Films: Decomposition of Organic Dyes and Efficient H2 Generation from Ethanol-Water Mixtures显示文摘与磅和 Pd nanoparticles 装饰的 TiO2 nanofibers 在各种各样的 photocatalytic 过程被综合了并且学习。在水里的器官的染料的分解的优秀 photocatalytic 行为,灵活独立纤维素 / 催化剂的表面上的器官的污点的降级合成电影并且在从乙醇用的氢的产生推迟了并且使不能调动催化剂被表明。基于 nanofiber 的 TiO2 材料的表演是在某情况 outperformstheir 的竞争 withand 常规基于 nanoparticle 的对应物。在所有情况中,装饰 Pd 的 TiO2 nanoparticles 和 nanofibers 证明了比他们的基于磅的对应物更有效,它能在在 TiO2 和金属 nanoparticles 之间的接触根据缩放 nano 的 Schottky 接口的形成被解释。形成纤维素 / 催化剂 composites 的可行性提供在大区域的涂层和独立电影利用光催化剂材料的一个新奇方法。 | Ming-Chung Wu Andras Sapi Anna Avila Maria Szabo Jussi Hiltunen Mika Huuhtanen Geza Toth Akos Kukovecz Zoltan Konya Riitta Keiski Wei-Fang Su Heli Jantunen Krisztian Kordas | 2011 | Nano Research2011，4，4： | 7 |
| 3 | Hepatocyte growth factor, a biomarker of macroangiopathy in diabetes mellitus显示文摘Atherosclerotic involvements are an essential causal element of prospect in diabetes mellitus(DM), with carotid atherosclerosis(CA) being a common risk-factor for prospective crisis of coronary artery diseases(CAD) and/or cerebral infarction(CI) in DM subjects. From another point of view, several reports have supplied augmenting proof that hepatocyte growth factor(HGF) has a physiopathological part in DM involvements. HGF has been a mesenchymal-derived polyphenic factor which modulates development, motion, and morphosis of diverse cells, and has been regarded as a humor intermediator of epithelial-mesenchymal interplays. The serum concentrations of HGF have been elevated in subjects with CAD and CI, especially during the acute phase of both disturbances. In our study with 89 type 2 DM patients, the association between serum concentrationsof HGF and risk-factors for macrovascular complicationsinclusive of CA were examined. The average of serumHGF levels in the subjects was more elevated than thereference interval. The serum HGF concentrations associated positively with both intimal-media thickness(IMT)(r = 0.24, P = 0.0248) and plaque score(r = 0.27, P =0.0126), indicating a relationship between the elevatedHGF concentrations and advancement of CA involvements. Multivariate statistical analysis accentuated thatserum concentrations of HGF would be associated inde-pendently with IMT(standardized = 0.28, P = 0.0499).The review indicates what is presently known regardingserum HGF might be a new and meaningful biomarkerof macroangiopathy in DM subjects. | Hiroyuki Konya Masayuki Miuchi Kahori Satani Satoshi Matsutani Taku Tsunoda Yuzo Yano Tomoyuki Katsuno Tomoya Hamaguchi Jun-Ichiro Miyagawa Mitsuyoshi Namba | 2014 | World Journal of Diabetes2014，5，5： | 5 |
| 4 | Biepicondylar fracture dislocation of the elbow joint concomitant with ulnar nerve injury显示文摘In this article, we present a case of humeral biepicondylar fracture dislocation concomitant with ulnar nerve injury in a seventeen year-old male patient. Physical examination of our patient in the emergency room revealed a painful, edematous and deformed-looking left elbow joint. Hypoesthesia of the little finger was also diagnosed on the left hand. Radiological assessment ended up with a posterior fracture dislocation of the elbow joint accompanied by intra-articular loose bodies. Open reduction-Internal fixation of the fracture dislocation and ulnar nerve exploration were performed under general anesthesia at the same session as surgical treatment of our patient. Physical therapy and rehabilitation protocol was implemented at the end of two weeks post-operatively. Union of the fracture lines, as well as the olecranon osteotomy site, was achieved at the end of four months post-operatively. Ulnar nerve function was fully restored without any sensory or motor loss. Range of motion at the elbow joint was 20-120 degrees at the latest follow-up. | M Nuri Konya Ahmet Aslan Hakan Sofu Timur Y?ld?r?m | 2013 | World Journal of Orthopedics2013，4，2： | 2 |
| 5 | Influence of pretreatment conditions on acidity of cobalt-based bimetallic systems in NaY zeolite显示文摘 | GUCZI L KONYA Z KOPPANY Z | 1997 | Catal Lett1997，44，12： | 1 |
| 6 | Outcomes for combined anterior and posterior surgical approaches for patients with muhisegmental cervical spondylotic myelopathy 显示文摘 | Konya D Ozgen S Gercek A | 2009 | Journal of Clinical Neuro- science2009，16，3： | 1 |
| 7 | PGH1 , the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activa- tor of the pro-inflammatory receptor CRTH2/DP2 显示文摘 | Schroder R Xue L Konya V | 2012 | PLoS One2012，7，33： | 1 |
| 8 | Long-time low-impact ball milling of multi wall carbon nanotubes显示文摘 | KUKOVECZ A KANYO T KONYA Z | 2005 | Carbon2005，43，5： | 1 |
| 9 | The role of osteopontin on calcium oxalate crystal formation显示文摘 | Konya E Umekawa T Iguchi M | 2003 | Eur Urol2003，43，： | 1 |
| 10 | Production of short carbon nanotubes with open tips by ball milling显示文摘 | Pierard N Fonseca A Konya Z | 2001 | Chemical Physics Letters2001，355，： | 1 |
| 11 | Inhibitory CD8+T cells in auloinunune disease显示文摘 | Suzuki M Konya C Goronzy JJ | 2008 | Hum Immunol2008，69，11： | 1 |
| 12 | Lumbar disc herniation in adolescence显示文摘 | Ozgen S Konya D Toktas OZ | 2007 | Pediatr Neurosurg2007，43，2： | 1 |
| 13 | Exports and growth:Granger causality analy- sis on OECD countries with a panel data approach显示文摘 | KONYA L | 2006 | Economic Modelling2006，23，6： | 1 |
| 14 | Effects of human papillomavirus type 16 oncoproteins on survivin gene expression 显示文摘 | Borbely AA Murvai M Konya J | 2006 | J Gen Virol2006，87，2： | 1 |
| 15 | UV-VIS Investigations on Co, Fe and Ni Incorporated into Sol-Gel SiO2-TiO2 Matrices显示文摘 | Kukovecz A Konya Z Monter D | 2001 | J Mol Struct2001，563，： | 1 |
| 16 | Prevalence of human Papillomavirus infections in our five year Data显示文摘 | Szikszay A Konya J | 2001 | Orv Hetil2001，142，24： | 1 |
| 17 | Production of short carbon nanotubes with open tips by ball milling显示文摘 | Pierard N Fonseca A Konya Z | 2001 | Chem Phys Lett2001，335，1： | 1 |
| 18 | 显示文摘 | Balazsi C Konya Z Weber F | 2003 | Materials Science Engineering C-Biomimetic and Supramolecular Systems2003，23，： | 1 |
| 19 | Microbial convention of mevinolin显示文摘 | Jekkel A Konya A Ilkoy E | 1997 | J Antibiotics1997，50，9： | 1 |
| 20 | Control of the outer di-ameter of thin carbon nanotubes synthesized by catalytic decom-pesition of hydrocarbons显示文摘 | Willems I Konya Z ColomerGF | 2000 | Chem Phys Lett2000，，317： | 1 |
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