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| 1 | Emergency department procedural sedation for primary electrical cardioversion — a comparison with procedural sedations for other reasons显示文摘BACKGROUND: Atrial fibrillation(AF) is the most common arrhythmia treated in the emergency department(ED), with primary electrical cardioversion(PEC) the preferred method of rhythm control. Anecdotally, patients undergoing ED procedural sedation(EDPS) for PEC differ from those requiring EDPS for other procedures: they are at higher risk of adverse events, and require fewer drugs and lower doses. We attempt to verify this using an EDPS registry at a Canadian, tertiary care teaching hospital.METHODS: This is a retrospective review of patients that underwent EDPS for the period of June 2006 to September 2014. We compared demographics, medication use and intra-procedural adverse events between those receiving EDPS for PEC for AF compared to that for other indications. We report the asssociation between AEs and predictors using logistic regression.RESULTS: A total of 4 867 patients were included, 714 for PEC for AF and 4 153 for other indications. PEC patients were more likely male(58.5% vs. 47.1%), older(59.5 years vs. 48.1 years), and less likely to be ASA I(46.6% vs. 69.0%). PEC patients received smaller doses of propofol and less likely to receive adjuvant analgesic therapy(11.5% vs. 78.2%). PEC patients were more likely to experience hypotension(27.6% vs. 16.5%) but respiratory AEs(apnea, hypoxia and airway intervention) were not different.CONCLUSION: EDPS for PEC differs from that conducted for other purposes: patients tend to be less healthy, receive smaller doses of medication and more likely to suffer hypotension without an increase in respiratory AEs. These factors should be considered when performing EDPS. | Michael Butler Patrick Froese Peter Zed George Kovacs Robert Mac Kinley Kirk Magee Mary-Lynn Watson Samuel G.Campbell | 2017 | World Journal of Emergency Medicine2017，8，3： | 6 |
| 2 | Geographical distribution of the incidence of gastric cancer in Bhutan显示文摘AIM: To estimate the prevalence of gastric cancer(GC) in a cohort of patients diagnosed with GC and to compare it with patients diagnosed with all other types of gastro-intestinal(GI) cancer during the same period.METHODS: Between 2008 and 2013,five-year period,the medical records of all GI cancer patients who underwent medical care and confirm diagnosis of cancer were reviewed at the National Referral Hospital,Thimphu which is the only hospital in the country where surgical and cancer diagnosis can be made. Demographic information,type of cancer,and the year of diagnosis were collected.RESULTS: There were a total of 767 GI related cancer records reviewed during the study period of which 354(46%) patients were diagnosed with GC. There were 413 patients with other GI cancer including; esophagus,colon,liver,rectum,pancreas,gall bladder,cholangiocarcinoma and other GI tract cancers. The GC incidence rate is approximately 0.9/10000 per year(367 cases/5years per 800000 people). The geographic distribution of GC was the lowest in the south region of Bhutan 0.3/10000 per year compared to the central region 1.4/10000 per year,Eastern region 1.2/10000 per year,and the Western region 1.1/10000 per year. Moreover,GC in the South part was significantly lower than the other GI cancer in the same region(8% vs 15%; OR = 1.8,95%CI: 1.3-3.1,P = 0.05). Among GC patients,38% were under the age of 60 years,mean age at diagnosis was 62.3(± 12.1) years with male-to-female ratio 1:0.5. The mean age among patients with all other type GI cancer was 60 years(± 13.2) and male-tofemale ratio of 1:0.7. At time of diagnosis of GC,342(93%) were at stage 3 and 4 of and by the year 2013; 80(23%) GC patients died compared to 31% death among patients with the all other GI cancer(P = 0.08).CONCLUSION: The incidence rate of GC in Bhutan is twice as high in the United States but is likely an underestimate rate because of unreported and undiagnosed cases in the villages. The high incidence of GC in Bhutan could be attributed to the high prevalence of Helicobacter pylori infection that we previously reported. The lowest incidence of GC in Southern part of the country could be due to the difference in the ethnicity as most of its population is of Indian and Nepal origin. Our current study emphasizes on the importance for developing surveillance and prevention strategies for GC in Bhutan. | Tashi Dendup James M Richter Yoshio Yamaoka Kinley Wangchuk Hoda M Malaty | 2015 | World Journal of Gastroenterology2015，21，38： | 4 |
| 3 | 青贮饲料中接种乳酸菌对黑白花奶牛甲烷排放和生产性能的影响显示文摘乳酸菌菌剂(LAB)通过增加青贮饲料中乳酸和其他有机酸类含量、降低饲料p H来提高饲料品质,防止酸败。本试验在青贮饲料中添加LAB,改变青贮饲料品质及其在瘤胃中的发酵条件,探索饲料中添加LAB对奶牛干物质采食量(DMI)、消化率、产奶量、牛奶品质和甲烷(CH4)排放量的影响。8头泌乳中期荷斯坦-黑白花杂交奶牛根据产奶量分成高产和低产两组,采用4×4拉丁方阵设计21 d试验。CH_4排放量采用间接量热法测量。各组青贮饲料(主要成分为黑麦草)分为空白组、长期添加LAB组、短期添加组(饲喂前16 h添加)和长短期综合添加组。所有饲料都由牧草青贮和复合物构成(干物质基础上的比例为7525)。长期添加组菌剂中植物乳杆菌、乳酸乳球菌和布氏乳杆菌比例为102070,短期添加组为乳酸乳球菌。试验结果表明,长期添加组和短期添加组对奶牛干物质摄入量(DMI)、中性洗涤纤维(NDF)、脂肪消化率、氮含量和能量平衡无显著影响,对乳成分(尤其是尿素)、乳脂肪、乳蛋白质和牛奶中微生物总数均无显著影响。但长期添加LAB使产奶量有增加趋势。长期添加组和短期添加组的奶牛中CH_4排放量无显著变化。其中,长期添加组中以k J·kg^(-1)为单位的代谢体重有提高趋势。试验结果得出引起动物生产性能改变的LAB最小添加量,包括长期和短期的。虽然其他研究表明青贮饲料中添加菌剂能对奶牛生产性能产生有利的显著影响,但本试验由于剂量、青贮饲料基底牧草选择和保存条件等因素的差异,未产生显著影响。 | Ellis J L Hindrichsen I K Klop G Kinley R D Milora N Bannink A Dijkstra J | 2016 | 饲料博览2016，0，9： | 3 |
| 4 | Sigma流量计在市政排水管网的成功应用显示文摘美国内珀维尔市通过安装准确耐用的流量计,消除了传感器的漂移,为流量监测系统提供了可靠的数据。通过这些可靠的流量和液位数据,能够分析市政排水管网的状态,判断入流和渗漏问题,优化对市政排水管网的维护和管理,执行最优的污水管道修复策略,最终减少因入流和渗漏问题对污水处理厂造成的流量冲击。 | 黄伟明 方闻 Marcia Kinley | 2010 | 中国给水排水2010，26，16： | 2 |
| 5 | Elevation of circulating and ventricular adrenomedullin in human congestive heart failure 显示文摘 | JOUGASAKI M WEI C M Mc KINLEY L J | 1995 | Circulation1995，92，3： | 2 |
| 6 | Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion显示文摘 | Kinley AW Weed SA Weaver AM | 2003 | Curr Biol2003，13，5： | 1 |
| 7 | Multivariate statistical monitoring of batch processes: an industrial case study of fermentation supervision显示文摘 | Albert S Kinley R D | 2001 | TRENDS in Biotechnolgy2001，19，2： | 1 |
| 8 | Endoscopic plant arfas-ciotoy versus traditional heel spur surgery:a prospective study 显示文摘 | Kinley S Frascone S Calderone D | 1993 | JFootAnkle Surg1993，32，6： | 1 |
| 9 | Endoseopie plantar fasciotoy versus traditional heel spursurgery:a prospeetive study 显示文摘 | Kinley S Fraseone S Calderone D | 1993 | Foot Ankle Surg1993，，6： | 1 |
| 10 | Hydrocarbon potential of the Barnett Shale (Mississippian) Delaware Basin, West Texas and Southeastem New Mexico 显示文摘 | Kinley T J Cook L W Breyer J A | 2008 | AAPG Bulletin2008，92，8： | 1 |
| 11 | Th17 cells mediate steroid-resistant airway inflammation and airway hyperresponsiveness in mice显示文摘 | Mc Kinley L Alcorn J F Peterson A | 2008 | J Immunol2008，181，6： | 1 |
| 12 | Giant cell tumor of the talus with secondary aneurysmal bone cyst显示文摘 | Kinley S Wiseman F Wertheimer SJ | 1993 | J Foot Ankle Surg1993，32，： | 1 |
| 13 | TH17 cells mediate steroid-resistant airway inflammation and airway显示文摘 | Mc Kinley L Alcorn JF Peterson A | 2008 | J Immunol2008，181，6： | 1 |
| 14 | En-doscopic plantar fasciotoy versus traditional heel spur surgery:a pro-spective study显示文摘 | Kinley S Frascone S Calderone D wertheimer SJ Squre MA | 1993 | J Foot Ankle Surg1993，32，6： | 1 |
| 15 | Hydrocarbon potential of the Barnett Shale(Mississippian),Delaware Basin,west Texas and southeastern New Mexico显示文摘 | Travis J Kinley | 2008 | AAPG Bulletin2008，92，8： | 1 |
| 16 | Normal versus supranormal oxygen delivery goals in shock resuscitation:the response is the same显示文摘 | Mc Kinley BA Kozar RA Cocanour CS | 2002 | J Trauma2002，53，： | 1 |
| 17 | Case-Based CBR:Capturing and Reusing Reasoning About Case Adaptation显示文摘 | Leake David B Kinley Andrew Wilson David | 1997 | InternationalJournal of Expert Systems1997，10，2： | 1 |
| 18 | Endoscopic plantar fas- ciotoy versus traditionalheel spur surgery: a prospective study显示文摘 | Kinley S Frascone S Calderone D | 1993 | J Foot Ankle Surg1993，32，6： | 1 |
| 19 | Hydrocarbon potential of the Barnett shale(Mississippian),Delaware basin,west Texas and southeastern New Mexico显示文摘 | Kinley T J Cook W L Breyer A J | 2008 | AAPG Bulletin2008，92，8： | 1 |
| 20 | A sex - specific comparison of major depressive disorder symptomatology in the canadian forces and the general population 显示文摘 | Erickson J Kinley D J Bolton JM | 2014 | Can J Psychiatry2014，59，7： | 1 |
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