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| 1 | Prognostic role of sensitive-to-apoptosis gene expression in rectal cancer显示文摘AIM:To investigate the association between prognosis of rectal cancer treated with chemoradiotherapy(CRT) and expression of sensitive-to-apoptosis(SAG),B-cell lymphoma-extra large(Bcl-X L) and Bcl-2 homologous antagonist/killer(Bak).METHODS:Real-time quantitative polymerase chain reaction was used to determine the expression of proteins of interest,namely SAG,Bcl-X L,Bak and β-actin,in rectal carcinoma patients who had a follow-up period of 3 years after CRT.Biopsy specimens were excised from the rectal tumor preceding CRT.RESULTS:SAG,Bcl-X L and Bak proteins showed significant correlations with each other.In multivariate analysis,patients with high vs low SAG expression showed a statistically significant difference in 2-year survival rates:56% vs 73%,respectively(P = 0.056).On the other hand,there were no significant correlations between the expression levels of all three genes and metastatic rates or tumor responses to CRT.Mean overall survival in the patients with elevated SAG expression was 27.1 mo ± 3.9 mo [95% confidence interval(CI):19.3-34.9],and in patients with reduced expression,it was 32.1 mo ± 2.5 mo(95% CI:27.3-36.9).The corresponding values for Bcl-X L were 28.0 mo ± 4.1 mo(95% CI:19.9-36.1) and 31.7 mo ± 2.9 mo(95% CI:26.0-37.5),and those for Bak were 29.8 mo ± 3.7 mo(95% CI:22.5-37.2) and 30.6 mo ± 2.4 mo(95% CI:25.5-35.0),respectively.CONCLUSION:Two-year survival rates significantly correlated with low SAG expression,and SAG may be a candidate gene for good prognosis,independent of therapeutic response of different individuals. | Sevgi A Ozden Hazan Ozyurt Zerrin Ozgen Olca Kilinc Mustafa Oncel Aylin E Gul Nimet Karadayi Nedime Serakinci Beki Kan Oya Orun | 2011 | World Journal of Gastroenterology2011，17，44： | 6 |
| 2 | Outcomes and predictors of vitrectomy and silicone oil tamponade in retinal detachments complicated by proliferative vitreoretinopathy显示文摘AIM:To evaluate outcomes and determine factors influencing the outcomes of vitrectomy with silicone oil(SO)endotamponade for the management of rhegmatogenous retinal detachment(RRD)complicated by advanced proliferative vitreoretinopathy(PVR).METHODS:This is a retrospective,interventional case series of eyes with PVR grade C associated RRD with or without prior surgery that underwent vitreoretinal surgery and SO tamponade.Eyes with a minimum follow-up of 6mo after SO extraction were included.Eyes were classified into three PVR subgroups according to severity and extension of proliferation.The influence of several preoperative,intraoperative and postoperative factors upon the functional and anatomical outcomes was assessed using multivariate logistic regression analysis.RESULTS:A hundred and one eyes of 101 patients that met the inclusion criteria were studied.Seventy-five of 101 eyes(74.3%)had successful retinal reattachment after one operation.Increased aqueous cell and flare at the first week exam had a statistically significant association with redetachment,recurrent membrane proliferation and keratopathy.Visual acuity improvement was significantly associated with faint postoperative aqueous inflammation values,primary vitrectomy and PVR outside of the posterior pole.CONCLUSION:Although encouraging anatomical and functional outcomes are achieved after vitrectomy and SO tamponade in eyes with RRD complicated by PVR,an increase in aqueous flare or cells at the first week follow-up is most likely to result in postoperative late complications.Primary vitrectomy,PVR associated with minimal posterior pole extension and absent to mild postoperative aqueous inflammation are associated with improved post-operative final visual acuity. | Kenan Sonmez Hilal Kilinc Hekimsoy | 2022 | International Journal of Ophthalmology(English edition)2022，15，8： | 2 |
| 3 | Structure and optical properties of Znl -xFexO thin films prepared by ultrasonic spray pyrolysis 显示文摘 | ALVER U KILINC T BACAKSIZ E | 2007 | Materials Science and Engineering B2007，138，： | 1 |
| 4 | Factors affecting the outcome of decompressive craniectomy for large hemispheric infarctions:a prospective cohort study显示文摘 | Kilincer C Asil T Utku U | 2005 | Acta Neurochir(Wien)2005，147，6： | 1 |
| 5 | Biomechanical e?valuation of the ventral and lateral surface shear strain dis?tributions in central compared with dorsolateral placement of cages for lumbar interbody fusion 显示文摘 | Sohn MJ Kayanja MM Kilincer C | 2006 | J Neurosurg Spine2006，4，3： | 1 |
| 6 | Effects of different nutrient so- lution formulations on morphological and biochemical character- istics of nursery fig trees brown in substrate culture 显示文摘 | Kilinc S S Ertan E Seferoglu S | 2007 | Scien- tia Horticulture2007，113，： | 1 |
| 7 | Frequency,distribution and severity of prevalent osteoporotic vertebral fractures in postmenopausal women显示文摘 | Kilincer C Kabayel DD Cagli B | 2013 | Turk Neurosurg2013，23，4： | 1 |
| 8 | Coenzyme Q10 concentrations in coronary artery disease显示文摘 | Yalcin A Kilinc E Sagcan A | 2004 | Clin Biochem2004，37，： | 1 |
| 9 | Exploring Students' Ideas About Risks and Benefits of Nuclear Power Using Risk Perception Theories显示文摘 | Kilinc A Boyes E Stanisstreet M | 2013 | Journal of Science Education and Technology2013，22，3： | 1 |
| 10 | Factors affecting the outcome of decompressive craniectomy for large hemispheric infarctions:a prospective cohort study显示文摘 | Kilincer C Asil T Utku U et a1 | 2005 | Acta Neurochir (Wien)2005，147，6： | 1 |
| 11 | Spinal metastasis of occult lung carcinoma causing cauda equina syndrome显示文摘 | Kotil K Kilinc BM Bilge T | 2007 | J Clin Neurosci2007，14，4： | 1 |
| 12 | Cutting edge:the Toll pathway is required for resistance to Gram-positive bacterial infections in Drosophila显示文摘 | Rutsehnmnn S Kilinc A Ferrandon D | 2002 | J Immuno12002，168，： | 1 |
| 13 | Syringocystadenoma papilliferum mimicking basal cell carcinoma on the lower eyelid: a case ~port 显示文摘 | Askar S Kilinc N Aytekin S | 2002 | Acta Chir Plast2002，44，4： | 1 |
| 14 | Electrical and VOC sensing properties of anatase and rutile TiOz nanotubes 显示文摘 | SENNIK E KILINC N OZTURK Z Z | 2014 | Journal of Alloys and Compounds2014，，616： | 1 |
| 15 | Comparison of unilateral spinal and continous spinal anesthesia for hip surgery in elderly patients显示文摘 | Kilinc LT Sivrikaya GU Eksioglu B | 2013 | Saudi J Anaesth2013，7，4： | 1 |
| 16 | Syringocystadenoma papilliferum mimicking basal cell carcinoma on the lower eyelid:a case report显示文摘 | Askar S Kilinc N Aytekin S | 2002 | Acta Chir Plast2002，44，4： | 1 |
| 17 | Totally tubeless percutaneous nephrolithotomy:is it safe and effective in preschool Children?显示文摘 | Ozturk A Guven S Kilinc M | 2010 | J Endourol2010，5，24： | 1 |
| 18 | Weapon selection using the AHP and TOPSIS methods under fuzzy environment显示文摘 | Dagdeviren M Yavuz S Kilinc N | 2009 | Expert Systems With Application2009，36，4： | 1 |
| 19 | Investigation of nitric ox- ide pterygium 显示文摘 | Ozdemir G Inanc F Kilinc M | 2005 | Canada Ophthalmol2005，40，6： | 1 |
| 20 | Propofol attenuates formation of lipid peroxides in tourniquet-induced ischemia-reperfusion injury显示文摘 | Kahraman S Kilinc K Dal D | 1997 | Br J Anaesth1997，78，30： | 1 |
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